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  glioblastoma [Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Mes]

Displaying 1-10 of 101 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395591Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A01glioblastoma [Mes]
GSE57872GSM1395592Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A02glioblastoma [Mes]
GSE57872GSM1395595Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A05glioblastoma [Mes]
GSE57872GSM1395597Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A07glioblastoma [Mes]
GSE57872GSM1395598Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A08glioblastoma [Mes]
GSE57872GSM1395600Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A10glioblastoma [Mes]
GSE57872GSM1395602Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_A12glioblastoma [Mes]
GSE57872GSM1395603Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B01glioblastoma [Mes]
GSE57872GSM1395605Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B03glioblastoma [Mes]
GSE57872GSM1395606Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_B04glioblastoma [Mes]

Gene rank in glioblastoma [Mes]

Displaying 81-90 of 5942 results.
Rank orderGene SymbolEnsembl ID
81BZW1ENSG00000082153
82MT2AENSG00000125148
83HNRNPCENSG00000092199
84MAGED1ENSG00000179222
85EFEMP1ENSG00000115380
86SPP1ENSG00000118785
87SRP9ENSG00000143742
88TROVE2ENSG00000116747
89PPT1ENSG00000131238
90PCSK5ENSG00000099139