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  glioblastoma [Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Mes]

Displaying 61-70 of 101 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395666Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_G04glioblastoma [Mes]
GSE57872GSM1395668Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_G06glioblastoma [Mes]
GSE57872GSM1395669Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_G07glioblastoma [Mes]
GSE57872GSM1395925Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_D11glioblastoma [Mes]
GSE57872GSM1395671Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_G09glioblastoma [Mes]
GSE57872GSM1395927Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_E01glioblastoma [Mes]
GSE57872GSM1395673Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_G11glioblastoma [Mes]
GSE57872GSM1395674Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_G12glioblastoma [Mes]
GSE57872GSM1395675Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_H01glioblastoma [Mes]
GSE57872GSM1395931Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_E05glioblastoma [Mes]

Gene rank in glioblastoma [Mes]

Displaying 61-70 of 5942 results.
Rank orderGene SymbolEnsembl ID
61GNB2L1
62TNCENSG00000041982
63PPIAENSG00000196262
64GPIENSG00000105220
65RPLP0ENSG00000089157
66RPL15ENSG00000174748
67MATR3ENSG00000015479
68ADAM9ENSG00000168615
69SPARCL1ENSG00000152583
70DSTENSG00000151914