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  glioblastoma [Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Mes]

Displaying 31-40 of 101 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395617Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C03glioblastoma [Mes]
GSE57872GSM1395873Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_H07glioblastoma [Mes]
GSE57872GSM1395619Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C05glioblastoma [Mes]
GSE57872GSM1395620Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C06glioblastoma [Mes]
GSE57872GSM1395621Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C07glioblastoma [Mes]
GSE57872GSM1395622Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C08glioblastoma [Mes]
GSE57872GSM1395623Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C09glioblastoma [Mes]
GSE57872GSM1395624Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C10glioblastoma [Mes]
GSE57872GSM1395880Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_A02glioblastoma [Mes]
GSE57872GSM1395625Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C11glioblastoma [Mes]

Gene rank in glioblastoma [Mes]

Displaying 41-50 of 5942 results.
Rank orderGene SymbolEnsembl ID
41ANXA2ENSG00000182718
42ATP5BENSG00000110955
43TMEM45AENSG00000181458
44NAMPTENSG00000105835
45ITGB8ENSG00000105855
46ARL6IP1ENSG00000170540
47CANXENSG00000127022
48RPL3ENSG00000100316
49YWHAZENSG00000164924
50PTNENSG00000105894