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  glioblastoma [Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Mes]

Displaying 1-10 of 101 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395762Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G04glioblastoma [Mes]
GSE57872GSM1395765Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G07glioblastoma [Mes]
GSE57872GSM1395766Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G08glioblastoma [Mes]
GSE57872GSM1395767Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G09glioblastoma [Mes]
GSE57872GSM1395769Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_G11glioblastoma [Mes]
GSE57872GSM1395775Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H05glioblastoma [Mes]
GSE57872GSM1395780Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H10glioblastoma [Mes]
GSE57872GSM1395782Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_H12glioblastoma [Mes]
GSE57872GSM1395814Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C08glioblastoma [Mes]
GSE57872GSM1395826Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D08glioblastoma [Mes]

Gene rank in glioblastoma [Mes]

Displaying 151-160 of 5942 results.
Rank orderGene SymbolEnsembl ID
151SETENSG00000119335
152PDIA6ENSG00000143870
153TFRCENSG00000072274
154MIR639
155NPM1ENSG00000181163
156SAT1ENSG00000130066
157CCND2ENSG00000118971
158HMGB1ENSG00000189403
159HSPA9ENSG00000113013
160NCSTNENSG00000162736