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  glioblastoma [Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Mes]

Displaying 41-50 of 101 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395626Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C12glioblastoma [Mes]
GSE57872GSM1395884Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_A06glioblastoma [Mes]
GSE57872GSM1395629Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_D03glioblastoma [Mes]
GSE57872GSM1395630Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_D04glioblastoma [Mes]
GSE57872GSM1395631Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_D05glioblastoma [Mes]
GSE57872GSM1395633Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_D07glioblastoma [Mes]
GSE57872GSM1395889Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH31_A11glioblastoma [Mes]
GSE57872GSM1395634Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_D08glioblastoma [Mes]
GSE57872GSM1395637Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_D11glioblastoma [Mes]
GSE57872GSM1395640Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_E02glioblastoma [Mes]

Gene rank in glioblastoma [Mes]

Displaying 5921-5930 of 5942 results.
Rank orderGene SymbolEnsembl ID
5921HTR3BENSG00000149305
5922TRPC5ENSG00000072315
5923MYO1GENSG00000136286
5924HHATLENSG00000010282
5925ALPPENSG00000163283
5926HOXC9ENSG00000180806
5927IQSEC2ENSG00000124313
5928SLC17A8ENSG00000179520
5929RNASE1ENSG00000129538
5930RGP1ENSG00000107185