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  glioblastoma [Neu+Mes]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Neu+Mes]

Displaying 1-10 of 19 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395616Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_C02glioblastoma [Neu+Mes]
GSE57872GSM1395638Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_D12glioblastoma [Neu+Mes]
GSE57872GSM1395642Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_E04glioblastoma [Neu+Mes]
GSE57872GSM1395651Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_F01glioblastoma [Neu+Mes]
GSE57872GSM1395662Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_F12glioblastoma [Neu+Mes]
GSE57872GSM1395672Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_G10glioblastoma [Neu+Mes]
GSE57872GSM1395686Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH28_H12glioblastoma [Neu+Mes]
GSE57872GSM1395687Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A01glioblastoma [Neu+Mes]
GSE57872GSM1395693Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A07glioblastoma [Neu+Mes]
GSE57872GSM1395694Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_A08glioblastoma [Neu+Mes]

Gene rank in glioblastoma [Neu+Mes]

Displaying 61-70 of 5942 results.
Rank orderGene SymbolEnsembl ID
61CALUENSG00000128595
62ATP5BENSG00000110955
63NRCAMENSG00000091129
64RPN2ENSG00000118705
65SYT11ENSG00000132718
66FXYD6ENSG00000137726
67CLIC4ENSG00000169504
68GNB2L1
69EIF1ENSG00000173812
70SKP1ENSG00000113558