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  glioblastoma [None]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [None]

Displaying 1-10 of 120 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395416Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_B06glioblastoma [None]
GSE57872GSM1395420Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_B10glioblastoma [None]
GSE57872GSM1395442Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_D08glioblastoma [None]
GSE57872GSM1395444Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_D10glioblastoma [None]
GSE57872GSM1395448Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_E02glioblastoma [None]
GSE57872GSM1395452Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_E06glioblastoma [None]
GSE57872GSM1395453Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_E07glioblastoma [None]
GSE57872GSM1395471Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G01glioblastoma [None]
GSE57872GSM1395472Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G02glioblastoma [None]
GSE57872GSM1395481Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G11glioblastoma [None]

Gene rank in glioblastoma [None]

Displaying 5911-5920 of 5942 results.
Rank orderGene SymbolEnsembl ID
5911LEF1ENSG00000138795
5912BRD1ENSG00000100425
5913DSC1ENSG00000134765
5914SERPINA1ENSG00000197249
5915APLNRENSG00000134817
5916MYO1GENSG00000136286
5917SYPENSG00000102003
5918CALB1ENSG00000104327
5919FAM182BENSG00000175170
5920ASB5ENSG00000164122