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  glioblastoma [Pro+Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro+Cla]

Displaying 1-10 of 20 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395508Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B02glioblastoma [Pro+Cla]
GSE57872GSM1395511Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B05glioblastoma [Pro+Cla]
GSE57872GSM1395516Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B10glioblastoma [Pro+Cla]
GSE57872GSM1395531Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_D01glioblastoma [Pro+Cla]
GSE57872GSM1395807Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C01glioblastoma [Pro+Cla]
GSE57872GSM1395564Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_F10glioblastoma [Pro+Cla]
GSE57872GSM1395825Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_D07glioblastoma [Pro+Cla]
GSE57872GSM1395835Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_E05glioblastoma [Pro+Cla]
GSE57872GSM1395581Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_H03glioblastoma [Pro+Cla]
GSE57872GSM1395854Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_F12glioblastoma [Pro+Cla]

Gene rank in glioblastoma [Pro+Cla]

Displaying 61-70 of 5942 results.
Rank orderGene SymbolEnsembl ID
61C6orf62ENSG00000112308
62EEF1GENSG00000254772
63PPP1CBENSG00000213639
64HSP90AA1ENSG00000080824
65ARL6IP1ENSG00000170540
66ITGB8ENSG00000105855
67PRDX1ENSG00000117450
68GPIENSG00000105220
69CNBPENSG00000169714
70HMGB1ENSG00000189403