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  glioblastoma [Pro+Cla]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro+Cla]

Displaying 1-10 of 20 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395401Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_A03glioblastoma [Pro+Cla]
GSE57872GSM1395403Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_A05glioblastoma [Pro+Cla]
GSE57872GSM1395411Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_B01glioblastoma [Pro+Cla]
GSE57872GSM1395425Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_C03glioblastoma [Pro+Cla]
GSE57872GSM1395434Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_C12glioblastoma [Pro+Cla]
GSE57872GSM1395435Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_D01glioblastoma [Pro+Cla]
GSE57872GSM1395450Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_E04glioblastoma [Pro+Cla]
GSE57872GSM1395468Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_F10glioblastoma [Pro+Cla]
GSE57872GSM1395508Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B02glioblastoma [Pro+Cla]
GSE57872GSM1395511Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26-2_B05glioblastoma [Pro+Cla]

Gene rank in glioblastoma [Pro+Cla]

Displaying 5891-5900 of 5942 results.
Rank orderGene SymbolEnsembl ID
5891S1PR1ENSG00000170989
5892ZNF691ENSG00000164011
5893APLNRENSG00000134817
5894ARMCX2ENSG00000184867
5895ASB5ENSG00000164122
5896C3ENSG00000125730
5897CDH13ENSG00000140945
5898CHI3L2ENSG00000064886
5899CRYGSENSG00000213139
5900CXCL3ENSG00000163734