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  glioblastoma [Pro+Neu]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro+Neu]

Displaying 1-5 of 5 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395801Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B07glioblastoma [Pro+Neu]
GSE57872GSM1395815Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C09glioblastoma [Pro+Neu]
GSE57872GSM1395427Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_C05glioblastoma [Pro+Neu]
GSE57872GSM1395703Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_B05glioblastoma [Pro+Neu]
GSE57872GSM1395480Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G10glioblastoma [Pro+Neu]

Gene rank in glioblastoma [Pro+Neu]

Displaying 21-30 of 5942 results.
Rank orderGene SymbolEnsembl ID
21MT-CYBENSG00000198727
22FXYD6ENSG00000137726
23ALDOAENSG00000149925
24ETV1ENSG00000006468
25UBBENSG00000170315
26SRIENSG00000075142
27RPN2ENSG00000118705
28DPYSL2ENSG00000092964
29B2MENSG00000166710
30HMGB1ENSG00000189403