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  glioblastoma [Pro+Neu]

Overall DesignOperative specimens from five glioblastoma patients (MGH26, MGH28, MGH29, MGH30, MGH31) were acutely dissociated, depleted for CD45+ inflammatory cells and then sorted as single cells (576 samples). Population controls for each tumor were isolated by sorting 2000-10000 cells and processed in parallel (5 population control samples). Single cells from two established cell lines, GBM6 and GBM8, were also sorted as single cells (192 samples).
SummaryWe report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.
Dataset viewGSE57872
PMID24925914

Samples in glioblastoma [Pro+Neu]

Displaying 1-5 of 5 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE57872GSM1395801Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_B07glioblastoma [Pro+Neu]
GSE57872GSM1395815Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH30_C09glioblastoma [Pro+Neu]
GSE57872GSM1395427Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_C05glioblastoma [Pro+Neu]
GSE57872GSM1395703Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH29_B05glioblastoma [Pro+Neu]
GSE57872GSM1395480Illumina HiSeq 2500Homo sapiensSingle cell mRNA-seq_MGH26_G10glioblastoma [Pro+Neu]

Gene rank in glioblastoma [Pro+Neu]

Displaying 31-40 of 5942 results.
Rank orderGene SymbolEnsembl ID
31FOSENSG00000170345
32RPL15ENSG00000174748
33PPIAENSG00000196262
34FTLENSG00000087086
35GPM6BENSG00000046653
36SEPT2ENSG00000168385
37SKP1ENSG00000113558
38HNRNPCENSG00000092199
39HNRNPA2B1ENSG00000122566
40SLC1A3ENSG00000079215