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  liver cancer cell

Overall Design6 single human HepG2 cell line cells were sequenced using the newly developed scTrio-seq, other 2 HepG2 cells were sequenced using scRNA-seq and other 2 HepG2 cells were sequenced using scRRBS as technique control. 6 single mouse embryonic stem cells (mESCs) were sequenced using the newly developted scTrio-seq. Meanwhile, two scRNA-seq and two scRRBS were also completed using two mESCs separately. 26 single cells from hepatocellular carcinoma were sequenced using scTrio-seq to analyze the regulation relations between three omics of cancer cells.
SummarySingle cell genome, DNA methylome, and transcriptome sequencing has been achieved separately. However, to analyze the regulation of RNA expression by genetic and epigenetic factors within an individual cell, it is necessary to analyze these omics simultaneously from the same single cell. Here we developed a single cell triple omics sequencing technique- scTrio-seq, to analyze the genome, DNA methylome, and transcriptome concurrently of a mammalian cell.
Dataset viewGSE65364
PMID26902283

Samples in liver cancer cell

Displaying 1-10 of 26 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65364GSM1593768Illumina HiSeq 2000Homo sapiensCa_01_RNAliver cancer cell
GSE65364GSM1593770Illumina HiSeq 2000Homo sapiensCa_02_RNAliver cancer cell
GSE65364GSM1593772Illumina HiSeq 2000Homo sapiensCa_03_RNAliver cancer cell
GSE65364GSM1593774Illumina HiSeq 2000Homo sapiensCa_04_RNAliver cancer cell
GSE65364GSM1593776Illumina HiSeq 2000Homo sapiensCa_05_RNAliver cancer cell
GSE65364GSM1593778Illumina HiSeq 2000Homo sapiensCa_06_RNAliver cancer cell
GSE65364GSM1593780Illumina HiSeq 2000Homo sapiensCa_07_RNAliver cancer cell
GSE65364GSM1593782Illumina HiSeq 2000Homo sapiensCa_08_RNAliver cancer cell
GSE65364GSM1593784Illumina HiSeq 2000Homo sapiensCa_09_RNAliver cancer cell
GSE65364GSM1593786Illumina HiSeq 2000Homo sapiensCa_10_RNAliver cancer cell

Gene rank in liver cancer cell

Displaying 1-10 of 15622 results.
Rank orderGene SymbolEnsembl ID
1MIR6723ENSG00000278791
2APOA2ENSG00000158874
3FTLENSG00000087086
4AMBPENSG00000106927
5SERPINA1ENSG00000197249
6APOC3ENSG00000110245
7RBP4ENSG00000138207
8UBBENSG00000170315
9ALDOBENSG00000136872
10HPENSG00000257017