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  zygote (2PN)-bad

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-bad

Displaying 11-11 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598286Illumina HiSeq 2000Homo sapiensS5zygote (2PN)-bad

Gene rank in zygote (2PN)-bad

Displaying 121-130 of 19195 results.
Rank orderGene SymbolEnsembl ID
121YWHABENSG00000166913
122JARID2ENSG00000008083
123CNBPENSG00000169714
124ASF1AENSG00000111875
125ARMC1ENSG00000104442
126TIAM1ENSG00000156299
127CCDC147
128CHEK1ENSG00000149554
129CAPZA1ENSG00000116489
130PSMA5ENSG00000143106