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  zygote (2PN)-bad

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-bad

Displaying 11-11 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598303Illumina HiSeq 2000Homo sapiensS22zygote (2PN)-bad

Gene rank in zygote (2PN)-bad

Displaying 151-160 of 19195 results.
Rank orderGene SymbolEnsembl ID
151GINS2ENSG00000131153
152RBMX2ENSG00000134597
153CCDC6ENSG00000108091
154CIR1ENSG00000138433
155TRIM59ENSG00000213186
156CD164ENSG00000135535
157EIF2AENSG00000144895
158BRCA2ENSG00000139618
159GDI2ENSG00000057608
160FN1ENSG00000115414