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  zygote (2PN)-bad

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-bad

Displaying 11-11 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598303Illumina HiSeq 2000Homo sapiensS22zygote (2PN)-bad

Gene rank in zygote (2PN)-bad

Displaying 41-50 of 19195 results.
Rank orderGene SymbolEnsembl ID
41EIF1ENSG00000173812
42TPT1ENSG00000133112
43TCL1AENSG00000100721
44NPM1ENSG00000181163
45NLRP9ENSG00000185792
46ADD3ENSG00000148700
47ESCO2ENSG00000171320
48CDK7ENSG00000134058
49ACTL8ENSG00000117148
50NLRP11ENSG00000179873