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  zygote (2PN)-bad

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-bad

Displaying 1-10 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598282Illumina HiSeq 2000Homo sapiensS1zygote (2PN)-bad
GSE65481GSM1598284Illumina HiSeq 2000Homo sapiensS3zygote (2PN)-bad
GSE65481GSM1598285Illumina HiSeq 2000Homo sapiensS4zygote (2PN)-bad
GSE65481GSM1598286Illumina HiSeq 2000Homo sapiensS5zygote (2PN)-bad
GSE65481GSM1598291Illumina HiSeq 2000Homo sapiensS10zygote (2PN)-bad
GSE65481GSM1598292Illumina HiSeq 2000Homo sapiensS11zygote (2PN)-bad
GSE65481GSM1598293Illumina HiSeq 2000Homo sapiensS12zygote (2PN)-bad
GSE65481GSM1598294Illumina HiSeq 2000Homo sapiensS13zygote (2PN)-bad
GSE65481GSM1598295Illumina HiSeq 2000Homo sapiensS14zygote (2PN)-bad
GSE65481GSM1598297Illumina HiSeq 2000Homo sapiensS16zygote (2PN)-bad

Gene rank in zygote (2PN)-bad

Displaying 11-20 of 19195 results.
Rank orderGene SymbolEnsembl ID
11H3F3BENSG00000132475
12PCNAENSG00000132646
13OTX2ENSG00000165588
14UHRF1ENSG00000276043
15NLRP4ENSG00000160505
16TAX1BP1ENSG00000106052
17KPNA7ENSG00000185467
18BTG4ENSG00000137707
19LIMA1ENSG00000050405
20TUBA1CENSG00000167553