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  zygote (2PN)-good

Overall DesignWe sequenced the transcriptomes of 22 human zygotes (2PN stage) embryos, of which 11 were predicted nonviable and 11 were predicted viable. We excluded 5 which had no siblings in this data set. From the remaining 17 embryos, we analyzed the set of genes that was differentially expressed between those predicted viable and those predicted nonviable.
SummaryWe sorted 2PN stage human embryos by predicted viability using a noninvasive measurement we previously developed. We then performed RNA-seq on each embryo (which was a single cell) and looked for differences in expression between viable and nonviable embryos.
Dataset viewGSE65481
PMID26904963

Samples in zygote (2PN)-good

Displaying 11-11 of 11 results.
SeriesSampleInstrumentOrganismTitleCell Source
GSE65481GSM1598302Illumina HiSeq 2000Homo sapiensS21zygote (2PN)-good

Gene rank in zygote (2PN)-good

Displaying 31-40 of 19195 results.
Rank orderGene SymbolEnsembl ID
31CUL5ENSG00000166266
32FAM46CENSG00000183508
33PAIP1ENSG00000172239
34B3GNT2ENSG00000170340
35HSP90AA1ENSG00000080824
36AURKAENSG00000087586
37TMSB4XENSG00000205542
38UNC13CENSG00000137766
39EIF1ENSG00000173812
40EIF5BENSG00000158417