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Gene View

General Information

APP[ENSG00000142192]

SynonymsAAA;ABETA;ABPP;AD1;APPI;CTFgamma;CVAP;PN-II;PN2
Descriptionamyloid beta precursor protein
Chromosome21q21.3
Database ReferenceMIM:104760 HGNC:620 HPRD:00100 Vega:OTTHUMG00000078438 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
APP expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell00787.161
CAF0219.64890.279
Endothelial cell0985.6082,785.573
Macrophage00550.989
melanoma001,464.314
melanoma tumor001,787.067
T-cell001,269.202
unresolved002,132.869
Displaying 21-28 of 28 results.
Comparing APP expression between groupsFDR
Macrophage VS melanoma2.60079848199113e-05
Macrophage VS unresolved0.00379333672734905
T-cell VS unresolved4.37883887207912e-05
melanoma tumor VS T-cell0.00735817383036138
melanoma tumor VS unresolved0.000312807131858774
melanoma VS T-cell1.67886813456661e-54
melanoma VS melanoma tumor1.77362370112126e-23
melanoma VS unresolved0.0376930312031164
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for APP

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]