Loading

Gene View

General Information

CXCR4[ENSG00000121966]

SynonymsCD184;D2S201E;FB22;HM89;HSY3RR;LAP-3;LAP3;LCR1;LESTR;NPY3R;NPYR;NPYRL;NPYY3R;WHIM;WHIMS
DescriptionC-X-C motif chemokine receptor 4
Chromosome2q21
Database ReferenceMIM:162643 HGNC:2561 HPRD:01217 Vega:OTTHUMG00000153583 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
CXCR4 expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell03,706.88422,951.481
CAF000
Endothelial cell008.89
Macrophage0385.9266,296.956
melanoma001,623.135
melanoma tumor02,083.77517,295.321
T-cell02,485.22519,500.026
unresolved008,087.877
Displaying 1-20 of 28 results.
Comparing CXCR4 expression between groupsFDR
B-cell VS CAFNS
B-cell VS Endothelial cell1.91450854935662e-59
B-cell VS Macrophage6.59265709858783e-22
B-cell VS T-cell3.68948529369326e-05
B-cell VS melanoma tumor8.0096824710773e-05
B-cell VS melanoma3.40148338170062e-52
B-cell VS unresolved2.48447182670904e-28
CAF VS Endothelial cellNS
CAF VS MacrophageNS
CAF VS T-cellNS
CAF VS melanoma tumorNS
CAF VS melanomaNS
CAF VS unresolvedNS
Endothelial cell VS Macrophage2.50474165711473e-10
Endothelial cell VS T-cell5.72093149694584e-233
Endothelial cell VS melanoma tumor1.46488257096793e-58
Endothelial cell VS melanoma0.00132798638379996
Endothelial cell VS unresolved1.33758521911027e-15
Macrophage VS T-cell4.77132632666017e-18
Macrophage VS melanoma tumor8.98320266715579e-09
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for CXCR4

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]