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General Information

GPNMB[ENSG00000136235]

SynonymsHGFIN;NMB
Descriptionglycoprotein nmb
Chromosome7p15
Database ReferenceMIM:604368 HGNC:4462 HPRD:05081 Vega:OTTHUMG00000022811 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
GPNMB expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell00123.929
CAF0186.9424,244.365
Endothelial cell0047.689
Macrophage0010,430.68
melanoma0874.2614,823.753
melanoma tumor006,093.953
T-cell001,123.232
unresolved0211.9792,619.965
Displaying 1-20 of 28 results.
Comparing GPNMB expression between groupsFDR
B-cell VS CAF0.000187709135117142
B-cell VS Endothelial cellNS
B-cell VS Macrophage3.17369425583362e-06
B-cell VS T-cell0.038905396162739
B-cell VS melanoma tumor2.22884328010515e-13
B-cell VS melanoma4.39432144731842e-120
B-cell VS unresolved6.15581402043401e-10
CAF VS Endothelial cell1.8946914146504e-09
CAF VS MacrophageNS
CAF VS T-cell0.0253238515315728
CAF VS melanoma tumorNS
CAF VS melanoma5.4157958887227e-07
CAF VS unresolvedNS
Endothelial cell VS Macrophage8.20348293893958e-10
Endothelial cell VS T-cellNS
Endothelial cell VS melanoma tumorNS
Endothelial cell VS melanoma1.03929110993695e-64
Endothelial cell VS unresolved8.95896925630439e-13
Macrophage VS T-cell0.00284029334330087
Macrophage VS melanoma tumor0.0239701408419447
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for GPNMB

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]