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General Information

GRN[ENSG00000030582]

SynonymsCLN11;GEP;GP88;PCDGF;PEPI;PGRN
Descriptiongranulin
Chromosome17q21.32
Database ReferenceMIM:138945 HGNC:4601 HPRD:00733 Vega:OTTHUMG00000181816 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
GRN expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell003,253.78
CAF0483.5421,234.394
Endothelial cell0857.12,179.109
Macrophage01,839.5986,324.118
melanoma0556.5774,066.536
melanoma tumor004,395.311
T-cell003,469.413
unresolved0287.8562,379.889
Displaying 1-20 of 28 results.
Comparing GRN expression between groupsFDR
B-cell VS CAFNS
B-cell VS Endothelial cell9.13583005822495e-05
B-cell VS Macrophage1.30876169609632e-12
B-cell VS T-cell8.04317021935162e-11
B-cell VS melanoma tumor0.0228253562080861
B-cell VS melanoma1.58982084076692e-48
B-cell VS unresolved0.00178176626687948
CAF VS Endothelial cell5.94166119269531e-05
CAF VS Macrophage4.32309454234643e-14
CAF VS T-cell0.00292941472059524
CAF VS melanoma tumorNS
CAF VS melanoma2.38897365811637e-06
CAF VS unresolved0.0479178753833988
Endothelial cell VS Macrophage1.07896793198531e-06
Endothelial cell VS T-cell5.61450178923826e-05
Endothelial cell VS melanoma tumor0.00671157584562149
Endothelial cell VS melanomaNS
Endothelial cell VS unresolved0.00786527340412749
Macrophage VS T-cell2.80479025074136e-08
Macrophage VS melanoma tumor3.41469349136217e-07
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for GRN

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]