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General Information

HLA-C[ENSG00000204525]

SynonymsD6S204;HLA-JY3;HLAC;HLC-C;MHC;PSORS1
Descriptionmajor histocompatibility complex, class I, C
Chromosome6p21.3
Database ReferenceMIM:142840 HGNC:4933 HPRD:00829 Vega:OTTHUMG00000031154 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
HLA-C expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell01,809.8858,504.04
CAF13.2572.5063,388.843
Endothelial cell454.3692,363.1810,116.36
Macrophage200.1723,225.5317,147.441
melanoma01,172.17514,341.641
melanoma tumor02,566.73712,614.408
T-cell03,706.11217,918.014
unresolved0944.82113,968.56
Displaying 1-20 of 28 results.
Comparing HLA-C expression between groupsFDR
B-cell VS CAF3.02540881772413e-17
B-cell VS Endothelial cellNS
B-cell VS Macrophage1.36540570874003e-05
B-cell VS T-cell5.63638726780907e-78
B-cell VS melanoma tumor4.92149435750051e-08
B-cell VS melanoma0.0030135293574825
B-cell VS unresolvedNS
CAF VS Endothelial cell2.22319635988019e-08
CAF VS Macrophage4.40701128315873e-13
CAF VS T-cell4.11086699164322e-71
CAF VS melanoma tumor1.72064904367685e-19
CAF VS melanoma1.66552664263138e-06
CAF VS unresolved0.00153605258313574
Endothelial cell VS MacrophageNS
Endothelial cell VS T-cell1.53698607427225e-05
Endothelial cell VS melanoma tumorNS
Endothelial cell VS melanoma0.0236814342868092
Endothelial cell VS unresolvedNS
Macrophage VS T-cellNS
Macrophage VS melanoma tumorNS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for HLA-C

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]