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| Synonyms | D6S222E;DMA;HLADM;RING6 |
| Description | major histocompatibility complex, class II, DM alpha |
|---|---|
| Chromosome | 6p21.3 |
| Database Reference | MIM:142855 HGNC:4934 HPRD:00830 Vega:OTTHUMG00000031173 |
| See related | THE HUMAN PROTEIN ATLAS |
| Dataset | GSE72056 |
| HLA-DMA expression in each cell group | Minimum Value (TPM) | Median Value (TPM) | Maximum Value (TPM) |
|---|---|---|---|
| B-cell | 0 | 705.797 | 6,275.571 |
| CAF | 0 | 0 | 80.882 |
| Endothelial cell | 0 | 0 | 1,151.383 |
| Macrophage | 0 | 1,006.325 | 4,264.761 |
| melanoma | 0 | 0 | 746.045 |
| melanoma tumor | 0 | 0 | 4,389.208 |
| T-cell | 0 | 0 | 3,890.459 |
| unresolved | 0 | 0 | 796.61 |
| Comparing HLA-DMA expression between groups | FDR |
|---|---|
| B-cell VS CAF | 1.70853778403651e-57 |
| B-cell VS Endothelial cell | 1.38390162340534e-22 |
| B-cell VS Macrophage | NS |
| B-cell VS T-cell | 9.68967013726776e-34 |
| B-cell VS melanoma tumor | 1.97020598232873e-07 |
| B-cell VS melanoma | 1.88040385845924e-72 |
| B-cell VS unresolved | 2.12656942671884e-36 |
| CAF VS Endothelial cell | 0.00795541645595973 |
| CAF VS Macrophage | 4.32309454234643e-14 |
| CAF VS T-cell | 4.57123480240827e-19 |
| CAF VS melanoma tumor | 4.88437920585349e-23 |
| CAF VS melanoma | NS |
| CAF VS unresolved | 7.04830612441139e-05 |
| Endothelial cell VS Macrophage | 2.34095781056939e-06 |
| Endothelial cell VS T-cell | NS |
| Endothelial cell VS melanoma tumor | 3.47555391273374e-05 |
| Endothelial cell VS melanoma | 0.0470752514789681 |
| Endothelial cell VS unresolved | NS |
| Macrophage VS T-cell | 3.64628247836381e-06 |
| Macrophage VS melanoma tumor | 0.0132784113262835 |
Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.
KEGG GO Others B-cell[326]
CAF[39]
Endothelial cell[40]
Macrophage[42]
melanoma[1071]
melanoma tumor[246]
T-cell[1302]
unresolved[96]
