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General Information

HLA-DRB1[ENSG00000196126]

SynonymsDRB1;DRw10;HLA-DR1B;HLA-DRB;SS1
Descriptionmajor histocompatibility complex, class II, DR beta 1
Chromosome6p21.3
Database ReferenceMIM:142857 HGNC:4948 HPRD:08349 Vega:OTTHUMG00000031196 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
HLA-DRB1 expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell01,640.3157,691.523
CAF00663.824
Endothelial cell008,471.055
Macrophage177.3944,877.419,058.822
melanoma00741.812
melanoma tumor070.60217,271.348
T-cell03.76,063.987
unresolved005,781.527
Displaying 1-20 of 28 results.
Comparing HLA-DRB1 expression between groupsFDR
B-cell VS CAF1.0122747635247e-36
B-cell VS Endothelial cell2.02327301028169e-07
B-cell VS Macrophage1.44892495534913e-17
B-cell VS T-cell1.42321258535726e-56
B-cell VS melanoma tumor1.16880648462468e-06
B-cell VS melanoma2.01420278060853e-56
B-cell VS unresolved2.67434396623569e-22
CAF VS Endothelial cell0.0046660577622198
CAF VS Macrophage4.4853110668985e-08
CAF VS T-cell2.47314602211351e-16
CAF VS melanoma tumor2.40421423692806e-11
CAF VS melanomaNS
CAF VS unresolved0.0293277594545976
Endothelial cell VS Macrophage1.14330045739562e-05
Endothelial cell VS T-cellNS
Endothelial cell VS melanoma tumorNS
Endothelial cell VS melanoma0.000125751987359452
Endothelial cell VS unresolvedNS
Macrophage VS T-cell1.8147124554363e-21
Macrophage VS melanoma tumor1.07936763314186e-05
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for HLA-DRB1

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]