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General Information

HLA-DRB1[ENSG00000196126]

SynonymsDRB1;DRw10;HLA-DR1B;HLA-DRB;SS1
Descriptionmajor histocompatibility complex, class II, DR beta 1
Chromosome6p21.3
Database ReferenceMIM:142857 HGNC:4948 HPRD:08349 Vega:OTTHUMG00000031196 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
HLA-DRB1 expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell01,640.3157,691.523
CAF00663.824
Endothelial cell008,471.055
Macrophage177.3944,877.419,058.822
melanoma00741.812
melanoma tumor070.60217,271.348
T-cell03.76,063.987
unresolved005,781.527
Displaying 21-28 of 28 results.
Comparing HLA-DRB1 expression between groupsFDR
Macrophage VS melanoma8.20145942956441e-12
Macrophage VS unresolved2.758962872563e-07
T-cell VS unresolvedNS
melanoma tumor VS T-cell1.99599629285402e-10
melanoma tumor VS unresolved0.000398098111849942
melanoma VS T-cell4.75792914664842e-84
melanoma VS melanoma tumor3.11099833211402e-27
melanoma VS unresolved4.8143094270655e-05
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for HLA-DRB1

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]