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General Information

HLA-DRB5[ENSG00000198502]

SynonymsHLA-DRB
Descriptionmajor histocompatibility complex, class II, DR beta 5
Chromosome6p21.3
Database ReferenceMIM:604776 HGNC:4953 HPRD:09209 Vega:OTTHUMG00000031027 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
HLA-DRB5 expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell0437.1294,009.856
CAF00417.277
Endothelial cell003,350.658
Macrophage02,314.0049,508.563
melanoma00248.86
melanoma tumor008,582.297
T-cell002,855.613
unresolved003,163.872
Displaying 1-20 of 28 results.
Comparing HLA-DRB5 expression between groupsFDR
B-cell VS CAF2.60348541096319e-23
B-cell VS Endothelial cell0.00336203409795001
B-cell VS Macrophage1.00044549415225e-19
B-cell VS T-cell8.33853666962136e-33
B-cell VS melanoma tumor0.00616597847419537
B-cell VS melanoma6.22600765226642e-66
B-cell VS unresolved6.3057329765488e-12
CAF VS Endothelial cell0.0250656282093315
CAF VS Macrophage1.33593181011792e-06
CAF VS T-cell1.9750882468042e-09
CAF VS melanoma tumor1.33877980026204e-06
CAF VS melanomaNS
CAF VS unresolvedNS
Endothelial cell VS Macrophage1.17082596507857e-05
Endothelial cell VS T-cellNS
Endothelial cell VS melanoma tumorNS
Endothelial cell VS melanoma3.27283687152251e-05
Endothelial cell VS unresolvedNS
Macrophage VS T-cell2.04853709905111e-18
Macrophage VS melanoma tumor8.20529082463503e-05
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for HLA-DRB5

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]