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General Information

HMGCS1[ENSG00000112972]

SynonymsHMGCS
Description3-hydroxy-3-methylglutaryl-CoA synthase 1
Chromosome5p12
Database ReferenceMIM:142940 HGNC:5007 HPRD:07515 Vega:OTTHUMG00000162231 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE75140

Gene Rank

Gene Expression

 

Displaying 1-9 of 9 results.
HMGCS1 expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
ESC H9[53 days]0461.1961,662.029
fetal human cortex 1[12 weeks post-conception]0439.4971,055.955
fetal human cortex 2[13 weeks post-conception]0453.6211,097.126
iPSC 409B2[33 days]191.334339.998655.526
iPSC 409B2[35 days]114.858341.819709.176
iPSC 409B2[37 days]161.737341.36863.537
iPSC 409B2[41 days]0333.134713.072
iPSC 409B2[58 days]0514.441812.498
iPSC 409B2[65 days]15.959474.1171,347.576
Displaying 1-20 of 36 results.
Comparing HMGCS1 expression between groupsFDR
ESC H9[53 days] VS fetal human cortex 1[12 weeks post-conception]0.0106854885120585
ESC H9[53 days] VS fetal human cortex 2[13 weeks post-conception]NS
ESC H9[53 days] VS iPSC 409B2[33 days]0.00233625163080398
ESC H9[53 days] VS iPSC 409B2[35 days]2.6125165585354e-07
ESC H9[53 days] VS iPSC 409B2[37 days]6.81588153823637e-07
ESC H9[53 days] VS iPSC 409B2[41 days]3.88818859627962e-07
ESC H9[53 days] VS iPSC 409B2[58 days]NS
ESC H9[53 days] VS iPSC 409B2[65 days]NS
fetal human cortex 1[12 weeks post-conception] VS fetal human cortex 2[13 weeks post-conception]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[33 days]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[35 days]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[37 days]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[41 days]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[58 days]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[65 days]NS
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[33 days]NS
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[35 days]0.00269335015721771
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[37 days]0.00568479290401331
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[41 days]0.00261303912897238
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[58 days]NS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for HMGCS1

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 ESC H9[53 days][96]
 fetal human cortex 1[12 weeks post-conception][164]
 fetal human cortex 2[13 weeks post-conception][62]
 iPSC 409B2[33 days][40]
 iPSC 409B2[35 days][68]
 iPSC 409B2[37 days][71]
 iPSC 409B2[41 days][74]
 iPSC 409B2[58 days][79]
 iPSC 409B2[65 days][80]