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General Information

ITK[ENSG00000113263]

SynonymsEMT;LPFS1;LYK;PSCTK2
DescriptionIL2 inducible T-cell kinase
Chromosome5q31-q32
Database ReferenceMIM:186973 HGNC:6171 HPRD:01746 Vega:OTTHUMG00000130245 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
ITK expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell0015.261
CAF000
Endothelial cell0047.299
Macrophage002.93
melanoma00152.864
melanoma tumor001,288.858
T-cell019.42,534.609
unresolved00772.87
Displaying 1-20 of 28 results.
Comparing ITK expression between groupsFDR
B-cell VS CAFNS
B-cell VS Endothelial cellNS
B-cell VS MacrophageNS
B-cell VS T-cell4.51886338318485e-68
B-cell VS melanoma tumor1.35211757103329e-10
B-cell VS melanoma0.0411225616265486
B-cell VS unresolved0.000645644971832197
CAF VS Endothelial cellNS
CAF VS MacrophageNS
CAF VS T-cellNS
CAF VS melanoma tumorNS
CAF VS melanomaNS
CAF VS unresolvedNS
Endothelial cell VS MacrophageNS
Endothelial cell VS T-cell1.07220194846156e-43
Endothelial cell VS melanoma tumor5.39664639998407e-08
Endothelial cell VS melanomaNS
Endothelial cell VS unresolved0.00716474163964324
Macrophage VS T-cell2.38423194738101e-78
Macrophage VS melanoma tumor1.39947758286385e-17
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for ITK

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]