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General Information

PLEK[ENSG00000115956]

SynonymsP47
Descriptionpleckstrin
Chromosome2p13.3
Database ReferenceMIM:173570 HGNC:9070 HPRD:15935 Vega:OTTHUMG00000129562 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
PLEK expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell001,780.601
CAF0054.161
Endothelial cell00291.419
Macrophage0623.8394,897.349
melanoma00149.557
melanoma tumor003,522.878
T-cell002,939.65
unresolved00519.112
Displaying 1-20 of 28 results.
Comparing PLEK expression between groupsFDR
B-cell VS CAF4.38202923198005e-14
B-cell VS Endothelial cell5.25083511131871e-06
B-cell VS Macrophage9.47727856869372e-08
B-cell VS T-cellNS
B-cell VS melanoma tumor0.000463311976069197
B-cell VS melanoma4.84552385038882e-18
B-cell VS unresolved8.54436438328958e-06
CAF VS Endothelial cellNS
CAF VS Macrophage1.78454726352736e-07
CAF VS T-cell2.14409733621686e-12
CAF VS melanoma tumor4.79366508218037e-17
CAF VS melanomaNS
CAF VS unresolved0.0380955106617013
Endothelial cell VS Macrophage6.55369051676555e-05
Endothelial cell VS T-cell0.000148220985830991
Endothelial cell VS melanoma tumor1.31503942867859e-08
Endothelial cell VS melanomaNS
Endothelial cell VS unresolvedNS
Macrophage VS T-cell5.07984768657909e-06
Macrophage VS melanoma tumor0.00182607438920307
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for PLEK

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]