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Gene View

General Information

PRAME[ENSG00000185686]

SynonymsCT130;MAPE;OIP-4;OIP4
Descriptionpreferentially expressed antigen in melanoma
Chromosome22q11.22
Database ReferenceMIM:606021 HGNC:9336 HPRD:05820 Vega:OTTHUMG00000151172 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
PRAME expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell001,158.003
CAF0026.67
Endothelial cell009.97
Macrophage00389.189
melanoma0666.2573,924.673
melanoma tumor002,516.506
T-cell001,009.063
unresolved0316.7282,286.989
Displaying 21-28 of 28 results.
Comparing PRAME expression between groupsFDR
Macrophage VS melanoma1.86465695527241e-86
Macrophage VS unresolved8.31099208397392e-09
T-cell VS unresolved0.000398680082306985
melanoma tumor VS T-cell0.0115085791627783
melanoma tumor VS unresolved0.00323394516588081
melanoma VS T-cell9.69434573825299e-62
melanoma VS melanoma tumor1.51580752387294e-47
melanoma VS unresolved2.02530072135481e-08
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for PRAME

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]