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General Information

PTGIS[ENSG00000124212]

SynonymsCYP8;CYP8A1;PGIS;PTGI
Descriptionprostaglandin I2 (prostacyclin) synthase
Chromosome20q13.13
Database ReferenceMIM:601699 HGNC:9603 HPRD:09046 Vega:OTTHUMG00000033077 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE72056

Gene Rank

Gene Expression

 

Displaying 1-8 of 8 results.
PTGIS expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
B-cell08.195194.709
CAF052.711,023.217
Endothelial cell05.3830.581
Macrophage03.88520.46
melanoma02.48158.316
melanoma tumor08.06450.267
T-cell07.46298.073
unresolved03.55138.944
Displaying 1-20 of 28 results.
Comparing PTGIS expression between groupsFDR
B-cell VS CAF7.09655108123817e-17
B-cell VS Endothelial cellNS
B-cell VS Macrophage0.00587032219550601
B-cell VS T-cellNS
B-cell VS melanoma tumorNS
B-cell VS melanoma3.81847495900668e-16
B-cell VS unresolvedNS
CAF VS Endothelial cell7.32524071293719e-15
CAF VS Macrophage5.44912827589579e-18
CAF VS T-cell1.09991157331712e-17
CAF VS melanoma tumor2.60813499394249e-08
CAF VS melanoma1.6824847395629e-28
CAF VS unresolved2.47816006376547e-10
Endothelial cell VS MacrophageNS
Endothelial cell VS T-cellNS
Endothelial cell VS melanoma tumorNS
Endothelial cell VS melanomaNS
Endothelial cell VS unresolvedNS
Macrophage VS T-cellNS
Macrophage VS melanoma tumorNS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for PTGIS

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 B-cell[326]
 CAF[39]
 Endothelial cell[40]
 Macrophage[42]
 melanoma[1071]
 melanoma tumor[246]
 T-cell[1302]
 unresolved[96]