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General Information

TOP2A[ENSG00000131747]

SynonymsTOP2;TP2A
Descriptiontopoisomerase (DNA) II alpha
Chromosome17q21.2
Database ReferenceMIM:126430 HGNC:11989 HPRD:00536 Vega:OTTHUMG00000155008 
See relatedTHE HUMAN PROTEIN ATLAS
DatasetGSE75140

Gene Rank

Gene Expression

 

Displaying 1-9 of 9 results.
TOP2A expression in each cell groupMinimum Value (TPM)Median Value (TPM)Maximum Value (TPM)
ESC H9[53 days]0340.7061,722.479
fetal human cortex 1[12 weeks post-conception]002,223.019
fetal human cortex 2[13 weeks post-conception]00662.006
iPSC 409B2[33 days]0290.543555.793
iPSC 409B2[35 days]0304.467726.198
iPSC 409B2[37 days]0316.43514.445
iPSC 409B2[41 days]018.239633.647
iPSC 409B2[58 days]00618.774
iPSC 409B2[65 days]06.074759.45
Displaying 1-20 of 36 results.
Comparing TOP2A expression between groupsFDR
ESC H9[53 days] VS fetal human cortex 1[12 weeks post-conception]0.00348679928901385
ESC H9[53 days] VS fetal human cortex 2[13 weeks post-conception]8.12269595301933e-05
ESC H9[53 days] VS iPSC 409B2[33 days]NS
ESC H9[53 days] VS iPSC 409B2[35 days]NS
ESC H9[53 days] VS iPSC 409B2[37 days]NS
ESC H9[53 days] VS iPSC 409B2[41 days]0.0215029367450396
ESC H9[53 days] VS iPSC 409B2[58 days]0.00241497806379714
ESC H9[53 days] VS iPSC 409B2[65 days]0.0365178055129103
fetal human cortex 1[12 weeks post-conception] VS fetal human cortex 2[13 weeks post-conception]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[33 days]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[35 days]0.0387337880493671
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[37 days]0.0281779538674086
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[41 days]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[58 days]NS
fetal human cortex 1[12 weeks post-conception] VS iPSC 409B2[65 days]NS
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[33 days]0.0251196534898236
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[35 days]0.00103325799499787
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[37 days]0.000626612489314634
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[41 days]0.0250230966733976
fetal human cortex 2[13 weeks post-conception] VS iPSC 409B2[58 days]NS
NS represents no significant differential expression between two groups was detected by using the BPSC method.

Top 100 positive and negative correlated genes for TOP2A

Top correlated genes were calculated by using Spearman rank correlation. Enrichment analysis can be performed on DAVID server using its API, while alternative links are also provided.

KEGG GO Others   

 ESC H9[53 days][96]
 fetal human cortex 1[12 weeks post-conception][164]
 fetal human cortex 2[13 weeks post-conception][62]
 iPSC 409B2[33 days][40]
 iPSC 409B2[35 days][68]
 iPSC 409B2[37 days][71]
 iPSC 409B2[41 days][74]
 iPSC 409B2[58 days][79]
 iPSC 409B2[65 days][80]