Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

3596

Name

IL13

Synonym

ALRH|BHR1|IL-13|P600;interleukin 13;IL13;interleukin 13

Definition

Bronchial hyperresponsiveness-1 (bronchial asthma)|allergic rhinitis|interleukin-13

Position

5q31

Gene Type

protein-coding

PAH Type

Description

PAH

Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension.

PAH

Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension.

PAH

IL-13 contributes to the development of pulmonary hypertension via an IL-13receptor alpha2-arginase 2-dependent pathway.
More detail of all Mouse literatures about IL13

Pathways and Diseases

Pathway

Jak-STAT signaling pathway;KEGG PATHWAY;hsa04630

Pathway

Fc epsilon RI signaling pathway;KEGG PATHWAY;hsa04664

Pathway

Glucocorticoid receptor regulatory network;PID Curated;200077

Pathway

Asthma;KEGG PATHWAY;hsa05310

Pathway

Cytokine-cytokine receptor interaction;KEGG PATHWAY;hsa04060

Pathway

gata3 participate in activating the th2 cytokine genes expression;PID BioCarta;100157

Pathway

IL12 signaling mediated by STAT4;PID Curated;200197

Pathway

Interleukin signaling pathway;PANTHER;P00036

Disease

atopy;GAD

Disease

Atopic asthma;GAD

Disease

allergic rhinitis;GAD

Disease

Atopy (total & specific IgE);GAD

Disease

gastric atrophy;GAD

Disease

Graves' disease;GAD

Disease

Periodontitis;FunDO

Disease

dermatitis and eczema;GAD

Disease

Graves disease;GAD

Disease

Mastocytosis, Systemic;GAD

Disease

malaria, plasmodium falciparum;GAD

Disease

Respiratory tract disease;FunDO

Disease

Ulcerative colitis;FunDO

Disease

Diabetes mellitus;FunDO

Disease

Amyotrophic lateral sclerosis;FunDO

Disease

Communicable disease;FunDO

Disease

immunologically hyper-reactive form of onchocerciasis (sowda);GAD

Disease

Sinusitis;FunDO

Disease

BHR;GAD

Disease

IMMUNE;GAD

Disease

Systemic scleroderma;FunDO

Disease

Total serum IgE. atopic dermatitis;GAD

Disease

psoriasis;GAD

Disease

PHARMACOGENOMIC;GAD

Disease

Asthma;GAD

Disease

Asthma;NHGRI

Disease

INFECTION;GAD

Disease

allergic reaction, betalactam;GAD

Disease

rhinitis;GAD

Disease

Asthma;KEGG DISEASE;H00079

Disease

diabetes, type 1;GAD

Disease

Psoriasis;NHGRI

Disease

asthma bronchodilator response IgE lung function;GAD

Disease

latex allergy;GAD

Disease

respiratory syncytial virus;GAD

Disease

Multiple sclerosis;FunDO

Disease

Total serum IgE;GAD

Disease

Bronchial hyperreactivity;FunDO

Disease

herpesvirus, Kaposi sarcoma-associated;GAD

Disease

Graves' disease;FunDO

Disease

Adenovirus infection;FunDO

Disease

Chronic obstructive airway disease;FunDO

Disease

atopic dermatitis;GAD

Disease

Graft-versus-host disease;KEGG DISEASE;H00084

Disease

Dermatitis;FunDO

Disease

Esophagitis;FunDO

Disease

nephrotic syndrome;GAD

Disease

Enteritis;FunDO

Disease

asthma IgE levels;GAD

Disease

Immune system diseases;KEGG DISEASE

Disease

onchocerciasis;GAD

Disease

lung function;GAD

Disease

chronic obstructive pulmonary disease/COPD;GAD

Disease

Allergic rhinitis, susceptibility to;OMIM

Disease

Allergies and autoimmune diseases;KEGG DISEASE

Disease

Ovary cancer;FunDO

Disease

serum IgE levels;GAD

Disease

Hodgkin's disease;FunDO

Disease

Asthma, susceptibility to;OMIM

Disease

RENAL;GAD

External Links

Links to Entrez Gene

3596

Links to all GeneRIF Items

3596

Links to iHOP

3596

Sequence Information

Nucleotide Sequence

>3596 : length: 441
atgcatccgctcctcaatcctctcctgttggcactgggcctcatggcgcttttgttgacc
acggtcattgctctcacttgccttggcggctttgcctccccaggccctgtgcctccctct
acagccctcagggagctcattgaggagctggtcaacatcacccagaaccagaaggctccg
ctctgcaatggcagcatggtatggagcatcaacctgacagctggcatgtactgtgcagcc
ctggaatccctgatcaacgtgtcaggctgcagtgccatcgagaagacccagaggatgctg
agcggattctgcccgcacaaggtctcagctgggcagttttccagcttgcatgtccgagac
accaaaatcgaggtggcccagtttgtaaaggacctgctcttacatttaaagaaacttttt
cgcgagggacagttcaactga

Protein Sequence

>3596 : length: 146
MHPLLNPLLLALGLMALLLTTVIALTCLGGFASPGPVPPSTALRELIEELVNITQNQKAP
LCNGSMVWSINLTAGMYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRD
TKIEVAQFVKDLLLHLKKLFREGQFN



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