| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3596 |
Name | IL13 |
Synonymous | ALRH|BHR1|IL-13|P600;interleukin 13;IL13;interleukin 13 |
Definition | Bronchial hyperresponsiveness-1 (bronchial asthma)|allergic rhinitis|interleukin-13 |
Position | 5q31 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for IL13 | |||
Transcription Factors [Top] |
|
Regulation From TransFac database |
IL-13(h) + IL-13Ralpha1(h) <==> IL-13(h):IL-13Ralpha1(h) (binding) | IL-13(h) + IL-13Ralpha1(h) + IL-4Ralpha(h) <==> IL-4Ralpha(h):IL-13Ralpha1(h):IL-13(h) (binding) | IL-13(h) + IL-13Ralpha2(h) <==> IL-13(h):IL-13Ralpha2(h) (binding) | IL-13(h) --> PLCgamma1(h){pY} (increase of phosphorylation) | IL-13(h) --> IRS-2(h){pY} (increase of phosphorylation) | IL-13(h) --> LIF(h) (decrease of secretion) | IL13(h) --> IL-13(h) (expression). | FcgammaRI alpha(h) --> IL-13(h) (decrease of secretion) | FcgammaRIIA(h) --> IL-13(h) (decrease of secretion) | FCgammaRIIIA(h) --> IL-13(h) (decrease of secretion) | IFNgamma(h) --> IL-13(h) (increase of secretion) | IL-13(h) --> Muc5AC(h) (increase of secretion) | IL13(h) --> IL-13(h) (expression). |
|---|
Post Transcriptional Modification [Top] | |||
|
Location (AA) |
PTM type |
Literature |
Database |
38 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 49 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 57 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 | 72 | N-linked (GlcNAc...) (Potential). | Swiss-Prot 53.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
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Chromosome |
Location |
Source |
|---|---|---|
chr5 |
Promoter: 132020264 - 132022264 | Agilent_014791 |
chr5 |
Promoter: 132020264 - 132022264 | GoldenGate_Methylation_Cancer_Panel_I |