Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

6093

Name

ROCK1

Synonymous

P160ROCK|ROCK-I;Rho-associated, coiled-coil containing protein kinase 1;ROCK1;Rho-associated, coiled-coil containing protein kinase 1

Definition

Rho kinase|p160 ROCK-1|p160-ROCK|renal carcinoma antigen NY-REN-35|rho-associated protein kinase 1|rho-associated, coiled-coil-containing protein kinase 1|rho-associated, coiled-coil-containing protein kinase I

Position

18q11.1

Gene Type

protein-coding

Gene Mutation:

GWAS results
PAH samples
Lung cancer

GWAS results   [Top]

There is no record for ROCK1

Lung cancer   [Top]

Mutation (Type; AA; Chr)

Site

Histology

p.K1267N; chr18:18534796-18534796

lungadenocarcinoma; carcinoma

p.R403H; chr18:18608740-18608740

lungsquamous_cell_carcinoma; carcinoma

p.A696T; chr18:18571194-18571194

lungsquamous_cell_carcinoma; carcinoma

p.?; chr18:18533756-18533756

lungsquamous_cell_carcinoma; carcinoma

p.A987S; chr18:18548777-18548777

lungadenocarcinoma; carcinoma

p.I1192F; chr18:18535145-18535145

lungadenocarcinoma; carcinoma

p.R349R; chr18:18619439-18619439

lungadenocarcinoma; carcinoma

p.R683L; chr18:18571232-18571232

lungadenocarcinoma; carcinoma

p.P1193S; chr18:18535142-18535142

lungnon_small_cell_carcinoma; carcinoma

p.D364G; chr18:18608857-18608857

lungadenocarcinoma; carcinoma

p.M128I; chr18:18629083-18629083

lungadenocarcinoma; carcinoma

p.?; chr18:18622205-18622205

lungsquamous_cell_carcinoma; carcinoma

p.E768A; chr18:18566912-18566912

lungadenocarcinoma; carcinoma

p.T233A; chr18:18622649-18622649

lungadenocarcinoma; carcinoma

p.T233A; chr18:18622649-18622649

lungadenocarcinoma; carcinoma

p.Q483E; chr18:18588119-18588119

lungsquamous_cell_carcinoma; carcinoma

p.S1100C; chr18:18546931-18546931

lungsquamous_cell_carcinoma; carcinoma

p.T1101T; chr18:18546927-18546927

lungadenocarcinoma; carcinoma

p.P354Q; chr18:18608887-18608887

lungadenocarcinoma; carcinoma

p.F1342F; chr18:18533574-18533574

lungsquamous_cell_carcinoma; carcinoma

p.D216Y; chr18:18624092-18624092

lungadenocarcinoma; carcinoma

p.T1112P; chr18:18546896-18546896

lungadenocarcinoma; carcinoma

p.S558L; chr18:18586524-18586524

lungadenocarcinoma; carcinoma

p.M713I; chr18:18571141-18571141

lungsquamous_cell_carcinoma; carcinoma

p.A1258A; chr18:18534823-18534823

lungadenocarcinoma; carcinoma

p.R197T; chr18:18625253-18625253

lungsquamous_cell_carcinoma; carcinoma

p.L892F; chr18:18550453-18550453

lungadenocarcinoma; carcinoma

p.L892F; chr18:18550453-18550453

lungadenocarcinoma; carcinoma


')