| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 841 |
Name | CASP8 |
Synonymous | ALPS2B|CAP4|Casp-8|FLICE|MACH|MCH5;caspase 8, apoptosis-related cysteine peptidase;CASP8;caspase 8, apoptosis-related cysteine peptidase |
Definition | FADD-homologous ICE/CED-3-like protease|FADD-like ICE|ICE-like apoptotic protease 5|MACH-alpha-1/2/3 protein|MACH-beta-1/2/3/4 protein|MORT1-associated ced-3 homolog|apoptotic cysteine protease|apoptotic protease Mch-5|caspase 8, apoptosis-related cystein |
Position | 2q33-q34 |
Gene Type | protein-coding |
Gene Mutation: | GWAS results PAH samples Lung cancer |
GWAS results [Top] | ||
There is no record for CASP8 | ||
Lung cancer [Top] | ||
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
p.L184L; chr2:202137405-202137405 |
lung | squamous_cell_carcinoma; carcinoma |
p.S355C; chr2:202149749-202149749 |
lung | adenocarcinoma; carcinoma |
p.S141*; chr2:202136259-202136259 |
lung | squamous_cell_carcinoma; carcinoma |
p.E292E; chr2:202149561-202149561 |
lung | squamous_cell_carcinoma; carcinoma |
p.N475I; chr2:202151250-202151250 |
lung | adenocarcinoma; carcinoma |
p.E56*; chr2:202131375-202131375 |
lung | adenocarcinoma; carcinoma |
p.S392*; chr2:202149860-202149860 |
lung | squamous_cell_carcinoma; carcinoma |
p.?; chr2:202149536-202149536 |
lung | squamous_cell_carcinoma; carcinoma |
p.E56*; chr2:202131375-202131375 |
lung | adenocarcinoma; carcinoma |
p.?; chr2:202137501-202137501 |
lung | adenocarcinoma; carcinoma |
p.E179D; chr2:202137390-202137390 |
lung | adenocarcinoma; carcinoma |
p.E179D; chr2:202137390-202137390 |
lung | adenocarcinoma; carcinoma |