| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5216 |
Name | PFN1 |
Synonym | ALS18;profilin 1;PFN1;profilin 1 |
Definition | epididymis tissue protein Li 184a|profilin I|profilin-1 |
Position | 17p13.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 12660 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | Hemostasis;Reactome;REACT:604 |
Pathway | erk and pi-3 kinase are necessary for collagen binding in corneal epithelia;PID BioCarta;100184 |
Pathway | Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810 |
Pathway | rho cell motility signaling pathway;PID BioCarta;100041 |
Pathway | Shigellosis;KEGG PATHWAY;hsa05131 |
Pathway | Axon guidance;Reactome;REACT:18266 |
Pathway | Cytoskeletal regulation by Rho GTPase;PANTHER;P00016 |
|
External Links |
|
Links to Entrez Gene | 5216 |
Links to all GeneRIF Items | 5216 |
Links to iHOP | 5216 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>5216 : length: 423 atggccgggtggaacgcctacatcgacaacctcatggcggacgggacctgtcaggacgcg gccatcgtgggctacaaggactcgccctccgtctgggccgccgtccccgggaaaacgttc gtcaacatcacgccagctgaggtgggtgtcctggttggcaaagaccggtcaagtttttac gtgaatgggctgacacttgggggccagaaatgttcggtgatccgggactcactgctgcag gatggggaatttagcatggatcttcgtaccaagagcaccggtggggcccccaccttcaat gtcactgtcaccaagactgacaagacgctagtcctgctgatgggcaaagaaggtgtccac ggtggtttgatcaacaagaaatgttatgaaatggcctcccaccttcggcgttcccagtac tga |
Protein Sequence |
>5216 : length: 140 MAGWNAYIDNLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVNITPAEVGVLVGKDRSSFY VNGLTLGGQKCSVIRDSLLQDGEFSMDLRTKSTGGAPTFNVTVTKTDKTLVLLMGKEGVH GGLINKKCYEMASHLRRSQY |