| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 7161 |
Name | TP73 |
Synonym | P73;tumor protein p73;TP73;tumor protein p73 |
Definition | p53-like transcription factor|p53-related protein |
Position | 1p36.3 |
Gene Type | protein-coding |
|
TSG scores |
Description |
| TUSON ranking | 16937 |
TUSON P-value | 1 |
|
Pathways and Diseases |
|
Pathway | atm signaling pathway;PID BioCarta;100235 |
Pathway | E2F transcription factor network;PID Curated;200027 |
Pathway | p53 pathway;PANTHER;P00059 |
Pathway | Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722 |
Pathway | Direct p53 effectors;PID Curated;200101 |
Pathway | p53 pathway by glucose deprivation;PANTHER;P04397 |
Pathway | P53 pathway feedback loops 1;PANTHER;P04392 |
Pathway | p53 pathway feedback loops 2;PANTHER;P04398 |
Pathway | p53 signaling pathway;KEGG PATHWAY;hsa04115 |
Pathway | Huntington disease;PANTHER;P00029 |
Disease | Drug abuse;FunDO |
Disease | Cancers;KEGG DISEASE |
Disease | esophageal cancer;GAD |
Disease | Fanconi's anemia;FunDO |
Disease | lung cancer;GAD |
Disease | PHARMACOGENOMIC;GAD |
Disease | breast cancer;GAD |
Disease | Hepatocellular carcinoma;KEGG DISEASE;H00048 |
Disease | head and neck cancer;GAD |
Disease | endometrial cancer;GAD |
Disease | CANCER;GAD |
Disease | Cancer;FunDO |
Disease | Cancers of the digestive system;KEGG DISEASE |
Disease | esophageal cancer gastric cardiac cancer;GAD |
Disease | Neuroblastoma;OMIM |
Disease | Leukoencephalopathy;FunDO |
|
External Links |
|
Links to Entrez Gene | 7161 |
Links to all GeneRIF Items | 7161 |
Links to iHOP | 7161 |
|
Sequence Information |
The sequences provided here are only the longest representative sequences, not covering all the isoforms. |
Nucleotide Sequence |
>7161 : length: 1764 atgctgtacgtcggtgaccccgcacggcacctcgccacggcccagttcaatctgctgagc agcaccatggaccagatgagcagccgcgcggcctcggccagcccctacaccccagagcac gccgccagcgtgcccacccactcgccctacgcacaacccagctccaccttcgacaccatg tcgccggcgcctgtcatcccctccaacaccgactaccccggaccccaccactttgaggtc actttccagcagtccagcacggccaagtcagccacctggacgtactccccgctcttgaag aaactctactgccagatcgccaagacatgccccatccagatcaaggtgtccaccccgcca cccccaggcaccgccatccgggccatgcctgtttacaagaaagcggagcacgtgaccgac gtcgtgaaacgctgccccaaccacgagctcgggagggacttcaacgaaggacagtctgct ccagccagccacctcatccgcgtggaaggcaataatctctcgcagtatgtggatgaccct gtcaccggcaggcagagcgtcgtggtgccctatgagccaccacaggtggggacggaattc accaccatcctgtacaacttcatgtgtaacagcagctgtgtagggggcatgaaccggcgg cccatcctcatcatcatcaccctggagatgcgggatgggcaggtgctgggccgccggtcc tttgagggccgcatctgcgcctgtcctggccgcgaccgaaaagctgatgaggaccactac cgggagcagcaggccctgaacgagagctccgccaagaacggggccgccagcaagcgtgcc ttcaagcagagcccccctgccgtccccgcccttggtgccggtgtgaagaagcggcggcat ggagacgaggacacgtactaccttcaggtgcgaggccgggagaactttgagatcctgatg aagctgaaagagagcctggagctgatggagttggtgccgcagccactggtggactcctat cggcagcagcagcagctcctacagaggccgagtcacctacagcccccgtcctacgggccg gtcctctcgcccatgaacaaggtgcacgggggcatgaacaagctgccctccgtcaaccag ctggtgggccagcctcccccgcacagttcggcagctacacccaacctggggcccgtgggc cccgggatgctcaacaaccatggccacgcagtgccagccaacggcgagatgagcagcagc cacagcgcccagtccatggtctcggggtcccactgcactccgccacccccctaccacgcc gaccccagcctcgtcagttttttaacaggattggggtgtccaaactgcatcgagtatttc acctcccaagggttacagagcatttaccacctgcagaacctgaccattgaggacctgggg gccctgaagatccccgagcagtaccgcatgaccatctggcggggcctgcaggacctgaag cagggccacgactacagcaccgcgcagcagctgctccgctctagcaacgcggccaccatc tccatcggcggctcaggggaactgcagcgccagcgggtcatggaggccgtgcacttccgc gtgcgccacaccatcaccatccccaaccgcggcggcccaggcggcggccctgacgagtgg gcggacttcggcttcgacctgcccgactgcaaggcccgcaagcagcccatcaaggaggag ttcacggaggccgagatccactga |
Protein Sequence |
>7161 : length: 587 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGP VLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSS HSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLG ALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFR VRHTITIPNRGGPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH |