Found 67 literature records

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Entrez ID	Description
53353	"The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein."
4221	The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation.
4221	Differential expression of multiple alternative spliceforms of the Men1 tumor suppressor gene in mouse.
7251	Overexpression of tumor susceptibility gene TSG101 in human papillary thyroid carcinomas.
5573	Regulatory subunit type I-alpha of protein kinase A (PRKAR1A): a tumor-suppressor gene for sporadic thyroid cancer.
5728	Silencing of the PTEN tumor-suppressor gene in anaplastic thyroid cancer.
23328	tumor suppressor gene possibly involved in tumorigenesis of breast and other solid cancers
1871	"E2F3 loss leads to an increase in the rate of tumor initiation. Finally, analysis of Rb(+/-); E2f3(+/-) mice shows that this tumor-suppressive function of E2F3 is dose dependent."
7161	p73 tumor-suppressor activity is impaired in human thyroid cancer.
5909	Rap1GAP protein levels are tightly regulated and it may have a role as a tumor suppressor
5371	Loss of the tumor suppressor PML in human cancers of multiple histologic origins.
5795	"A candidate tumor suppressor gene because its expression was blocked in rat and human thyroid transformed cells, and its restoration reverted their neoplastic phenotype."
7068	TRbeta gene could function as a tumor suppressor gene. TRbeta could serve as a novel therapeutic target in thyroid cancer.
141	Silencing of the putative maternally imprinted tumor suppressor gene ARHI serves as a key early event in follicular thyroid carcinogenesis.
79577	Human parafibromin is a nucleocytoplasmic tumor suppressor protein which regulates cyclin D1/PRAD1 expression.
79577	The parafibromin tumor suppressor protein is part of a human Paf1 complex.
4221	that regulation of cyclin-dependent kinase inhibitor transcription by cooperative interaction between menin and MLL plays a central role in menin's activity as a tumor suppressor
7474	Wnt-5a serves as an antagonist to the canonical Wnt-signaling pathway with tumor suppressor activity in differentiated thyroid carcinomas.
11186	The tumor suppressor RASSF1A in human carcinogenesis: an update.
4436	"Tumor suppressor gene, hMSH2, may play an important role as a putative coactivator in ER alpha dependent gene expression."
79577	findings link the tumor suppressor parafibromin to the transcription elongation and RNA processing pathway as a PAF1 complex- and RNA polymerase II-bound protein.
11186	Methylation of the tumor suppressor gene RASSF1A in human tumors.
79577	Identification of a functional bipartite nuclear localization signal in the tumor suppressor parafibromin.
5915	Down-regulation of the tumor suppressor gene retinoic acid receptor beta2 through the phosphoinositide 3-kinase/Akt signaling pathway.
7078	"Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer. we first demonstrated the functional consequence of methylation of several recently identified tumor suppressor genes, including those for tissue inhibitor of metalloproteinase-3 (TIMP3), SLC5A8, death-associated protein kinase (DAPK) and retinoic acid receptor beta2 (RARbeta2). "
160728	Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer.
1612	Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer.
5915	Association of aberrant methylation of tumor suppressor genes with tumor aggressiveness and BRAF mutation in papillary thyroid cancer.
5268	[Role of the class II tumor suppressor gene maspin in thyroid carcinogenesis].
4221	Phosphorylation of the menin tumor suppressor protein on serine 543 and serine 583.
1029	Clinicopathological roles of alterations of tumor suppressor gene p16 in papillary thyroid carcinoma.
79577	These experiments identify for the first time a proapoptotic activity of endogenous parafibromin likely to be important in its role as a tumor suppressor and show a functional role for the NLS of parafibromin in this activity.
79577	Parafibromin tumor suppressor enhances cell growth in the cells expressing SV40 large T antigen.
54756	Inhibitory effect of hSef on cell proliferation combined with consistent downregulation in human carcinoma indicates a tumor suppressor-like role for Sef.
6794	Tumor suppressor LKB1 inhibits activation of signal transducer and activator of transcription 3 (STAT3) by thyroid oncogenic tyrosine kinase rearranged in transformation (RET)/papillary thyroid carcinoma (PTC).
4221	The expression changes associated with the loss of the tumor suppressor menin provide insights into the defective organogenesis observed during early embryonic development in Men1-null mouse embryos.
79577	The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3.
1031	P18 is a tumor suppressor gene involved in human medullary thyroid carcinoma and pheochromocytoma
79577	The parafibromin tumor suppressor protein HRPT2 inhibits cell proliferation by repression of the c-myc proto-oncogene
7428	von Hippel-Lindau tumor suppressor gene-dependent mRNA stabilization of the survival factor parathyroid hormone-related protein in human renal cell carcinoma by the RNA-binding protein HuR.
4221	Decreased expression and promoter methylation of the menin tumor suppressor in pancreatic ductal adenocarcinoma.
644943	RASSF10 may encode a novel epigenetically inactivated candidate tumor suppressor gene in thyroid carcinogenesis.
7068	TRs could function as tumor suppressors in a mouse model of metastatic follicular thyroid cancer.
79577	The simultaneous loss of nucleolar localization and acquisition of a growth stimulatory phenotype with the L95P mutation raise the possibility that parafibromin must interact with targets in the nucleolus to fully execute its tumor suppressor functions.
9770	Results suggest that RASSF2 encodes a novel epigenetically inactivated candidate tumor suppressor gene in thyroid carcinogenesis.
84651	ECRG2 is a novel member of the Kazal-type serine protease inhibitor family and may function as a tumor suppressor gene regulating the protease cascades during carcinogenesis and invasion of esophageal cancer.
7068	"microRNAs up-regulated in papillary thyroid carcinoma tumors directly inhibit the expression of THRB, an important tumor suppressor gene"
5602	results suggest that MAPK10 may have a proapoptotic function and could function as a tumor-suppressor gene in chromophobe renal cell carcinoma
54206	Mitogen-inducible gene-6 is a multifunctional adaptor protein with tumor suppressor-like activity in papillary thyroid cancer.
4485	"the oncogenic effect of BRAF(V600E) is associated with the inhibition of MST1 tumor suppressor pathways, and that the activity of RASSF1A-MST1-FoxO3 pathways determines the phenotypes of BRAF(V600E) tumors."

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