Trait name | Trait full name | Panel | Author | Year | Case* | Control | # TAG set | Top 3 Tissu-cell type: p (chi2) |
---|---|---|---|---|---|---|---|---|
2 Hour Glucose | 2-Hour Glucose | ETC | Saxena | 2010 | NA | 15234 | 2 | AdultGallbladder_Endothelial cell: p = 4.16e-5 Madissoon_2020_spleen_T CD8 gd: p = 1.03e-4 FetalMuscle_Fetal skeletal muscle cell: p = 2.24e-4 |
ADHD | Attention Deficit Hyperactivity Disorder | ETC | Demontis | 2017 | 19099 | 34194 | 4 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 1.17e-10 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 2.20e-10 Lake_2017_FrontalCortex_Excitatory neuron 5b: p = 7.01e-9 |
Age At Menarche | Age At Menarche | ETC | Perry | 2014 | NA | 182413 | 3 | Lake_2017_VisualCortex_Excitatory neuron 4: p = 3.28e-12 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 5.88e-10 Lake_2017_VisualCortex_Excitatory neuron 1: p = 1.73e-9 |
Age At Menopause | Age At Menopause | ETC | Day | 2015 | NA | 2545 | 3 | Madissoon_2020_lung_NK Dividing: p = 3.49e-5 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.03e-4 VentoTormo_2018_decidua_decidual natural killer cell (dNK3): p = 2.28e-4 |
Alzheimers | Alzheimer's Disease | ETC | Lambert | 2013 | 17008 | 37154 | 4 | VentoTormo_2018_decidua_decidual macrophage (dM1): p = 1.82e-13 Madissoon_2020_lung_Macrophage MARCOneg: p = 3.65e-11 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.23e-9 |
Clozapine Induced Agranulocytosis | Clozapine Induced Agranulocytosis | ETC | Goldstein | 2014 | 161 | 1196 | 2 | AdultBoneMarrow_Antigen presenting cell (RPS high): p = 3.62e-5 AdultBladder_Monocyte: p = 7.15e-5 FetalLiver_B cell: p = 7.98e-5 |
Depressive Symptoms | Depressive Symptoms | ETC | Okbay | 2016 | 122210 | 58835 | 2 | Lake_2017_VisualCortex_Inhibitory neuron 8: p = 6.14e-5 Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 2.60e-4 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 2.81e-4 |
Hemoglobin A1c | Hemoglobin A1c | ETC | Soranzo | 2010 | NA | 46368 | 4 | Madissoon_2020_spleen_T cell dividing: p = 1.31e-8 Madissoon_2020_lung_DC Monocyte Dividing: p = 1.62e-8 Madissoon_2020_spleen_Plasmablast: p = 1.96e-7 |
Internalizing Problems | Internalizing Problems | ETC | Benke | 2014 | NA | 4596 | 2 | Lake_2017_VisualCortex_Excitatory neuron 5b: p = 1.75e-4 Lake_2017_VisualCortex_Excitatory neuron 3d: p = 9.00e-4 Lake_2017_VisualCortex_Excitatory neuron 4: p = 9.00e-4 |
MDD | Major Depressive Disorder | ETC | Wray | 2018 | 16823 | 25632 | 4 | Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 1.15e-7 Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.66e-7 Lake_2017_VisualCortex_Inhibitory neuron 7: p = 1.60e-6 |
Neuroticism Symptoms | Neuroticism Symptoms | ETC | Okbay | 2016 | NA | 170911 | 3 | Lake_2017_VisualCortex_Excitatory neuron 5b: p = 1.01e-13 Lake_2017_VisualCortex_Excitatory neuron 1: p = 9.44e-11 Lake_2017_FrontalCortex_Excitatory neuron 5b: p = 6.03e-9 |
Obsessive Compulsive Disorder | Obsessive Compulsive Disorder | ETC | Arnold | 2017 | 2688 | 7037 | 2 | Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 3.76e-5 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 4.01e-5 Lake_2017_VisualCortex_Inhibitory neuron 4b: p = 3.53e-4 |
Rheumatoid Arthritis | Rheumatoid Arthritis | ETC | Stahl | 2010 | 5539 | 20169 | 4 | Madissoon_2020_oesophagus_B CD27pos: p = 1.07e-14 AdultRectum_B cell: p = 1.45e-13 AdultTemporalLobe_Macrophage: p = 2.22e-13 |
Subjective Well Being | Subjective Well Being | ETC | Okbay | 2016 | NA | 298420 | 3 | Lake_2017_VisualCortex_Excitatory neuron 4: p = 4.77e-8 Lake_2017_VisualCortex_Excitatory neuron 1: p = 5.34e-7 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 9.49e-7 |
Type 2 Diabetes | Type 2 Diabetes | ETC | Morris | 2012 | 12171 | 56862 | 3 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 2.31e-7 Segerstolpe_2016_PancreaticIslets_pancreatic ductal cell: p = 7.72e-6 Enge_2017_Pancreas_pancreatic ductal cell: p = 6.43e-5 |
Anxiety | Anxiety Continuous | ETC | Otowa | 2016 | NA | 18186 | 2 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 1.20e-5 Madissoon_2020_lung_Muscle cells: p = 3.36e-4 FetalStomach_Fetal mesenchymal progenitor: p = 6.95e-4 |
Autism | Autism Europeans | ETC | Psychiatric-Genomics-Consortium | 2017 | 6197 | 7377 | 2 | Lake_2017_VisualCortex_Excitatory neuron 5a: p = 1.60e-8 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 5.88e-6 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.06e-5 |
Birth Weight | Birth Weight European | ETC | Horikoshi | 2016 | NA | 133903 | 3 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 1.16e-9 Voigt_2019_retina_2_Choriocapillaris: p = 2.15e-9 Voigt_2019_retina_2_Vein cell 2: p = 1.41e-8 |
Blood Lipids | High Density Lipoprotein | ETC | Teslovich | 2010 | NA | 99900 | 3 | VentoTormo_2018_decidua_glandular epithelial cell (Epi2): p = 1.16e-9 Madissoon_2020_lung_Macrophage MARCOpos: p = 3.30e-8 MacParland_2018_liver_Hepatocyte: p = 3.09e-6 |
Blood Lipids | Low Density Lipoprotein | ETC | Teslovich | 2010 | NA | 95454 | 3 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 7.64e-9 VentoTormo_2018_decidua_decidual macrophage (dM1): p = 1.31e-7 Madissoon_2020_lung_Macrophage MARCOneg: p = 4.62e-7 |
Blood Lipids | Total Cholesterol | ETC | Teslovich | 2010 | NA | 100184 | 3 | VentoTormo_2018_decidua_decidual macrophage (dM1): p = 1.68e-10 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 3.10e-10 FetalFemaleGonad_Macrophage: p = 1.94e-7 |
Blood Lipids | Triglycerides | ETC | Teslovich | 2010 | NA | 96598 | 3 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.19e-13 VentoTormo_2018_decidua_decidual macrophage (dM1): p = 5.56e-9 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 5.56e-9 |
BMI | BMI European | ETC | Locke | 2015 | NA | 234069 | 3 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 2.22e-7 Lake_2017_VisualCortex_Excitatory neuron 3c: p = 5.96e-7 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 9.65e-7 |
Bone Mineral Density | Femoral Neck Bone Mineral Density | ETC | Zheng | 2015 | NA | 26320 | 4 | VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 3.10e-9 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 4.00e-7 VentoTormo_2018_decidua_placental extravillous trophoblast cell (EVT): p = 7.02e-7 |
Bone Mineral Density | Forearm Bone Mineral Density | ETC | Zheng | 2015 | NA | 6627 | 2 | Madissoon_2020_spleen_NK FCGR3Apos: p = 3.38e-7 Madissoon_2020_spleen_T CD8 MAIT: p = 2.66e-6 Madissoon_2020_lung_NK: p = 4.21e-6 |
Educational Attainment | Education Years All | ETC | Okbay | 2016 | NA | 293723 | 0 | Lake_2017_VisualCortex_Excitatory neuron 3a: p = 7.06e-13 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 7.06e-13 Lake_2017_VisualCortex_Excitatory neuron 1: p = 2.68e-12 |
Estimated Glomerular Filtration Rate | Chronic Kidney Disease | ETC | Pattaro | 2016 | 12385 | 104780 | 4 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 5.58e-5 Madissoon_2020_lung_Macrophage MARCOpos: p = 1.20e-4 Madissoon_2020_spleen_T cell dividing: p = 2.62e-4 |
Glycemic Traits | Fasting Glucose | ETC | Dupuis | 2010 | NA | 46186 | 4 | VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 1.42e-6 Madissoon_2020_spleen_CD34 progenitor: p = 1.22e-5 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 2.10e-5 |
Glycemic Traits | Fasting Insulin | ETC | Dupuis | 2010 | NA | 38238 | 2 | VentoTormo_2018_decidua_decidual macrophage (dM2): p = 1.46e-6 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 4.63e-6 VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 2.39e-5 |
Inflammatory Bowel Disease European | Crohn's disease | ETC | Liu | 2015 | 5956 | 14927 | 3 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.13e-16 Madissoon_2020_lung_DC 2: p = 2.13e-14 VentoTormo_2018_decidua_decidual macrophage (dM1): p = 2.92e-12 |
Inflammatory Bowel Disease European | Inflammatory Bowel Disease | ETC | Liu | 2015 | 12882 | 21770 | 3 | VentoTormo_2018_decidua_plasmacytoid dendritic cell (DC2): p = 1.69e-14 VentoTormo_2018_decidua_monocyte: p = 6.00e-14 Madissoon_2020_oesophagus_Mono macro: p = 2.17e-13 |
Inflammatory Bowel Disease European | Ulcerative Colitis | ETC | Liu | 2015 | 6968 | 20464 | 3 | AdultStomach_Dendritic cell: p = 2.25e-12 Madissoon_2020_lung_Monocyte: p = 7.35e-12 Madissoon_2020_oesophagus_Mono macro: p = 1.04e-11 |
Leptin | Leptin Not Adjusted For BMI | ETC | Kilpelainen | 2016 | NA | 32161 | 2 | Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 9.91e-7 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.11e-5 Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.11e-5 |
Reproductive Behavior | Age First Birth Pooled | ETC | Barban | 2016 | NA | 238064 | 4 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 2.03e-7 Lake_2017_VisualCortex_Inhibitory neuron 4b: p = 1.07e-5 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 3.71e-5 |
Smoking | Cigarettes Per Day | ETC | Furberg | 2010 | NA | 38181 | 2 | AdultTransverseColon_Stromal cell: p = 2.80e-4 Madissoon_2020_spleen_CD34 progenitor: p = 3.70e-4 Madissoon_2020_spleen_Macrophage: p = 6.88e-4 |
BIP | Bipolar disorder | ETC | Stahl | 2018 | 20352 | 31358 | 3 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 2.09e-16 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 3.48e-13 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 2.57e-11 |
SCZ | Schizophrenia | ETC | Ripke | 2014 | 32405 | 42221+í | 2 | Lake_2017_VisualCortex_Excitatory neuron 3a: p = 9.19e-16 Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.85e-15 Lake_2017_VisualCortex_Excitatory neuron 1: p = 1.09e-13 |
T1D | Type 1 Diabetes | ETC | Bradfield | 2011 | 9934 | 16956 | 3 | Madissoon_2020_oesophagus_B CD27pos: p = 4.77e-14 AdultTemporalLobe_Macrophage: p = 2.32e-12 Voigt_2019_retina_1_T/NK cell: p = 1.81e-11 |
PAN | Pancreatic Cancer | ETC | Amundadottir | 2009 | 1771 | 1805 | 2 | Lake_2017_VisualCortex_Inhibitory neuron 8: p = 1.37e-4 Lake_2017_VisualCortex_Inhibitory neuron 1c: p = 1.01e-3 FetalPancreas_Endothelial cell: p = 1.03e-3 |
COL | SSGAC_College | ETC | Rietveld | 2013 | NA | 101069 | 3 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 3.39e-9 Lake_2017_VisualCortex_Excitatory neuron 1: p = 1.13e-8 Lake_2017_VisualCortex_Excitatory neuron 4: p = 9.50e-7 |
HGB | Hemoglobin Concentration | ETC | Astle | 2016 | NA | 173480 | 1 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.56e-12 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 3.07e-10 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 3.82e-9 |
MCHC | Mean Corpuscular Hemoglobin Concentration | ETC | Astle | 2016 | NA | 173480 | 2 | FetalSpinalCord_Erythroid cell: p = 5.73e-14 FetalAdrenalGland_Erythroid cell: p = 1.85e-12 FetalFemaleGonad_Erythroid cell: p = 1.04e-11 |
PBC | Primary Biliary Cirrhosis | ETC | Cordell | 2015 | 2764 | 10475 | 3 | Madissoon_2020_lung_DC activated: p = 1.21e-15 Madissoon_2020_oesophagus_B CD27pos: p = 1.23e-15 Madissoon_2020_lung_DC 1: p = 2.70e-14 |
SLE | Systemic Lupus Erythematosus | ETC | Bentham | 2015 | 7219 | 15991 | 3 | Placenta_Macrophage: p = 1.30e-16 Madissoon_2020_oesophagus_B CD27pos: p = 1.39e-16 Madissoon_2020_oesophagus_Dendritic Cells: p = 2.93e-16 |
RHR | CAD Resting Heart Rate | ETC | Eppinga | 2016 | NA | 265046 | 2 | VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 3.88e-12 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 7.57e-12 VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 1.35e-11 |
T1D CA | Type1Diabetes (Childhood adiposity age < 17) | ETC | Censin | 2017 | 5913 | 8828 | 3 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.65e-15 Madissoon_2020_oesophagus_B CD27pos: p = 2.02e-14 Madissoon_2020_lung_T CD8 CytT: p = 6.81e-14 |
EOC | Epithelial Ovarian Cancer | ETC | Phelan | 2017 | 25509 | 40941 | 4 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 3.47e-5 Madissoon_2020_oesophagus_Endothelia vascular arterial: p = 1.23e-4 Enge_2017_Pancreas_type B pancreatic cell: p = 1.55e-4 |
AUD | Alcohol Dependency | ETC | Walters | 2018 | 11569 | 34999 | 2 | VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 1.82e-4 Lake_2017_VisualCortex_Excitatory neuron 1: p = 2.05e-4 VentoTormo_2018_decidua_conventional dendritic cell (DC1): p = 3.09e-4 |
MS | Multiple Sclerosis | ETC | Patsopoulos | 2017 | 14802 | 26703 | 2 | Madissoon_2020_oesophagus_B CD27pos: p = 2.71e-27 Madissoon_2020_oesophagus_T CD4: p = 7.31e-23 Madissoon_2020_oesophagus_B CD27neg: p = 4.06e-22 |
SCZ | Schizophrenia | ETC | Pardinas | 2018 | 40675 | 64643 | 1 | Lake_2017_VisualCortex_Excitatory neuron 4: p = 3.43e-19 Lake_2017_VisualCortex_Excitatory neuron 3a: p = 9.46e-17 Lake_2017_VisualCortex_Excitatory neuron 1: p = 4.20e-15 |
CEL | Celiac Disease | ETC | Trynka | 2011 | 12041 | 12228 | 4 | Madissoon_2020_lung_DC activated: p = 3.75e-10 Madissoon_2020_oesophagus_T CD8: p = 1.47e-9 AdultThyroid_T cell: p = 2.64e-9 |
Glycine level | Glycine levels, both male and female | ETC | Jia | 2019 | NA | 30118 | 2 | Lake_2017_FrontalCortex_Astrocyte: p = 3.20e-3 CordBloodCD34P_Neutrophil: p = 8.15e-3 VentoTormo_2018_decidua_CD16-negative natural killer cell (NK CD16-): p = 8.49e-3 |
Handedness | Handedness, right-handed vs non-right-handed | ETC | Kovel | 2019 | 293857 | 37180 | 3 | Lake_2017_VisualCortex_Excitatory neuron 3c: p = 4.04e-8 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 6.48e-6 AdultStomach_Dendritic cell: p = 8.01e-6 |
Ambidextrousness | Ambidextrousness | ETC | Kovel | 2019 | 5324 | 325713 | 2 | VentoTormo_2018_decidua_placental extravillous trophoblast cell (EVT): p = 9.64e-5 Madissoon_2020_spleen_T cell dividing: p = 1.07e-4 VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 2.55e-4 |
Handedness | Handedness, left-handed vs non-left-handed | ETC | Kovel | 2019 | 31856 | 299181 | 4 | Madissoon_2020_spleen_T CD4 reg: p = 4.26e-7 FetalAdrenalGland_Fetal mesenchymal progenitor: p = 2.59e-6 Enge_2017_Pancreas_mesenchymal cell: p = 2.26e-5 |
Parkinsons | Parkinsons disease, age of onset | ETC | Blauwendraat | 2019 | NA | 17996 | 2 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 1.56e-6 Madissoon_2020_lung_Blood vessel: p = 9.96e-5 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 1.51e-4 |
Active | Time to most active 10 hours | ETC | Jones | 2019 | NA | 85670 | 2 | Lake_2017_VisualCortex_Excitatory neuron 5a: p = 2.89e-9 Lake_2017_VisualCortex_Excitatory neuron 4: p = 2.33e-7 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 4.18e-7 |
Sleep | Sleep efficiency | ETC | Jones | 2019 | NA | 84810 | 3 | Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.98e-7 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 3.70e-7 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 2.79e-6 |
Sleep | Sleep duration variability | ETC | Jones | 2019 | NA | 84810 | 2 | FetalEyes_Fetal mesenchymal progenitor: p = 5.73e-5 FetalFemaleGonad_Fetal mesenchymal progenitor: p = 7.85e-5 AdultUterus_Stromal cell: p = 1.84e-4 |
Sleep | Sleep duration | ETC | Jones | 2019 | NA | 85449 | 3 | Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 3.10e-7 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 5.09e-7 Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.34e-6 |
Sleep | Sleep time to midpoint | ETC | Jones | 2019 | NA | 84810 | 2 | VentoTormo_2018_decidua_decidual macrophage (dM2): p = 1.79e-5 Madissoon_2020_spleen_DC 1: p = 2.26e-5 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 2.89e-5 |
Sleep | Sleep time to least active 5 hours | ETC | Jones | 2019 | NA | 85205 | 2 | Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.47e-7 FetalBrain_Fetal neuron: p = 5.22e-6 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 1.10e-5 |
Sleep | Diurnal inactivity | ETC | Jones | 2019 | NA | 84757 | 3 | Lake_2017_VisualCortex_Excitatory neuron 8: p = 1.30e-8 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.11e-6 Lake_2017_FrontalCortex_Excitatory neuron 8: p = 9.01e-6 |
Sleep | Sleep number of episodes | ETC | Jones | 2019 | NA | 84810 | 3 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.29e-12 Lake_2017_VisualCortex_Excitatory neuron 4: p = 2.45e-12 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 9.87e-11 |
Facial attractiveness | Facial attractiveness, male raters | ETC | Hu | 2019 | NA | 3928 | 1 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 7.39e-6 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 4.59e-5 FetalKidney_Macrophage: p = 1.16e-4 |
Facial attractiveness | Facial attractiveness, female raters | ETC | Hu | 2019 | NA | 3928 | 2 | FetalKidney_Macrophage: p = 2.17e-6 FetalSkin_Macrophage: p = 2.13e-5 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 3.81e-5 |
Facial attractiveness | Facial attractiveness of males, male raters | ETC | Hu | 2019 | NA | 1792 | 2 | FetalIntestine_Hepatocyte/Endodermal cell: p = 3.10e-4 Madissoon_2020_oesophagus_Epi basal: p = 5.75e-4 Segerstolpe_2016_PancreaticIslets_acinar cell: p = 6.61e-4 |
Facial attractiveness | Facial attractiveness of females, female raters | ETC | Hu | 2019 | NA | 2062 | 2 | Madissoon_2020_spleen_DC plasmacytoid: p = 6.07e-5 Lake_2017_VisualCortex_Excitatory neuron 3c: p = 6.27e-5 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 7.70e-5 |
Facial attractiveness | Facial attractiveness of males, female raters | ETC | Hu | 2019 | NA | 1792 | 2 | Segerstolpe_2016_PancreaticIslets_acinar cell: p = 8.44e-5 AdultTransverseColon_Enterocyte: p = 9.83e-5 Lake_2017_CerebellarHemisphere_Endothelial cell: p = 2.04e-4 |
Facial attractiveness | Facial attractiveness of females, male raters | ETC | Hu | 2019 | NA | 2062 | 1 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.05e-5 AdultGallbladder_Macrophage: p = 5.45e-5 AdultTransverseColon_Macrophage: p = 3.06e-4 |
Asthma | Asthma, adult-onset | ETC | Ferreira | 2019 | 26582 | 300671 | 3 | Madissoon_2020_oesophagus_T CD4: p = 4.80e-15 Madissoon_2020_oesophagus_B CD27pos: p = 5.58e-14 FetalLiver_Dendritic cell: p = 1.88e-13 |
Asthma | Asthma, childhood-onset | ETC | Ferreira | 2019 | 13962 | 300671 | 2 | Madissoon_2020_oesophagus_T CD4: p = 1.10e-14 Madissoon_2020_spleen_T CD8 MAIT: p = 1.99e-13 Madissoon_2020_lung_DC activated: p = 4.65e-13 |
Neuroticism | General factor of neuroticism | ETC | Hill | 2019 | NA | 270059 | 3 | Lake_2017_FrontalCortex_Excitatory neuron 2: p = 2.53e-15 Lake_2017_FrontalCortex_Excitatory neuron 1: p = 2.63e-13 Lake_2017_FrontalCortex_Excitatory neuron 5b: p = 1.74e-12 |
Neuroticism | Worry-vulnerability-special-factor-of-neuroticism | ETC | Hill | 2019 | NA | 270059 | 3 | Lake_2017_VisualCortex_Excitatory neuron 5a: p = 2.53e-12 Lake_2017_VisualCortex_Excitatory neuron 1: p = 4.80e-12 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 3.15e-11 |
Neuroticism | Anxiety-tension-special-factor-of-neuroticism | ETC | Hill | 2019 | NA | 270059 | 3 | Lake_2017_VisualCortex_Excitatory neuron 5a: p = 2.53e-12 Lake_2017_VisualCortex_Excitatory neuron 1: p = 4.80e-12 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 3.15e-11 |
Na/K ratio | Urinary sodium to potassium ratio | ETC | Zanetti | 2019 | NA | 108942 | 3 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 5.89e-7 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 8.96e-7 Voigt_2019_retina_2_Artery: p = 2.59e-6 |
K/C ratio | Urinary potassium to creatinine ratio | ETC | Zanetti | 2019 | NA | 218435 | 3 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.56e-7 VentoTormo_2018_decidua_decidual macrophage (dM1): p = 4.68e-7 Madissoon_2020_spleen_DC plasmacytoid: p = 3.17e-6 |
Sleep | Sleep duration, short sleep | ETC | Dashti | 2019 | 106192 | 305742 | 3 | Lake_2017_VisualCortex_Excitatory neuron 5a: p = 2.56e-19 Lake_2017_VisualCortex_Excitatory neuron 1: p = 8.62e-17 Lake_2017_VisualCortex_Excitatory neuron 4: p = 3.47e-16 |
Sleep | Sleep duration, long sleep | ETC | Dashti | 2019 | 34184 | 305742 | 4 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 2.65e-10 Lake_2017_VisualCortex_Excitatory neuron 3a: p = 8.53e-7 Madissoon_2020_lung_Macrophage Dividing: p = 5.59e-6 |
Sleep | Sleep duration | ETC | Dashti | 2019 | NA | 446118 | 2 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 3.38e-20 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 1.37e-14 Lake_2017_FrontalCortex_Excitatory neuron 1: p = 2.21e-14 |
Glycine level | Glycine level | ETC | Wittemans | 2019 | NA | 80003 | 4 | MacParland_2018_liver_Hepatocyte: p = 1.31e-9 Madissoon_2020_oesophagus_Epi suprabasal: p = 5.93e-5 AdultKidney_Epithelial cell: p = 1.90e-4 |
CTS | Carpal tunnel syndrome | ETC | Wiberg | 2019 | 12312 | 389344 | 3 | Madissoon_2020_spleen_T CD8 MAIT: p = 2.04e-7 FetalThymus_Dendritic cell: p = 2.42e-7 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 4.01e-7 |
MI/CF | Meconium ileus in cystic fibrosis | ETC | Gong | 2019 | 1115 | 5655 | 2 | Enge_2017_Pancreas_acinar cell: p = 6.95e-6 FetalAdrenalGland_Fetal fibroblast: p = 9.32e-5 Braga_2020_lung_Endothelium: p = 9.55e-5 |
Insomnia | Insomnia symptoms, never-rarely vs sometimes usually | ETC | Lane | 2019 | 345022 | 108357 | 3 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 6.89e-9 Lake_2017_VisualCortex_Excitatory neuron 3a: p = 6.89e-9 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 3.68e-8 |
Chronotype | Chronotype | ETC | Jones | 2019 | NA | 449734 | 1 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 1.31e-15 Lake_2017_VisualCortex_Excitatory neuron 3a: p = 1.31e-15 Lake_2017_VisualCortex_Excitatory neuron 4: p = 2.29e-14 |
Morning person | Morning person | ETC | Jones | 2019 | 252287 | 150908 | 2 | Lake_2017_VisualCortex_Excitatory neuron 5b: p = 1.29e-19 Lake_2017_VisualCortex_Excitatory neuron 1: p = 5.59e-19 Lake_2017_VisualCortex_Excitatory neuron 4: p = 4.82e-18 |
BMI | Normal body mass index vs thin control, adult vs thin adult | ETC | McKay | 2019 | 6460 | 1471 | 2 | Lake_2017_VisualCortex_Excitatory neuron 5a: p = 3.77e-5 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.16e-4 Madissoon_2020_lung_Macrophage Dividing: p = 1.70e-4 |
Obesity | Obesity, extreme obese children vs control adult | ETC | McKay | 2019 | 1456 | 6460 | 2 | Madissoon_2020_oesophagus_Epi upper: p = 3.47e-6 VentoTormo_2018_decidua_proliferating decidual natural killer cell (dNK p): p = 5.11e-5 FetalPancreas_Fetal stromal cell: p = 1.77e-4 |
Obesity | Obese children vs thin adults | ETC | McKay | 2019 | 1471 | 1456 | 3 | Madissoon_2020_spleen_CD34 progenitor: p = 2.15e-5 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 2.10e-4 VentoTormo_2018_decidua_decidual natural killer cell (dNK1): p = 3.27e-4 |
Vitiligo | Vitiligo late onset | ETC | Jin | 2019 | 1467 | 19156 | 4 | Madissoon_2020_oesophagus_B CD27pos: p = 4.52e-12 Madissoon_2020_spleen_B mature: p = 7.75e-11 Madissoon_2020_oesophagus_B CD27neg: p = 8.45e-11 |
Vitiligo | Vitiligo early onset | ETC | Jin | 2019 | 704 | 9031 | 4 | Madissoon_2020_lung_DC 1: p = 1.48e-12 Madissoon_2020_lung_DC activated: p = 7.07e-12 Madissoon_2020_oesophagus_B CD27pos: p = 1.24e-10 |
Body fat distribution | Body fat distribution, leg fat ratio, male | ETC | Andersen | 2019 | NA | 116138 | 3 | VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 2.35e-11 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 2.99e-10 Madissoon_2020_lung_Fibroblast: p = 6.28e-10 |
Body fat distribution | Body fat distribution-trunk-fat-ratio-male | ETC | Andersen | 2019 | NA | 116138 | 3 | VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 3.73e-11 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 6.39e-11 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 2.56e-8 |
Body fat distribution | Body fat distribution-arm-fat-ratio-female | ETC | Andersen | 2019 | NA | 116138 | 1 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 2.55e-9 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 4.05e-8 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 4.49e-7 |
Body fat distribution | Body fat distribution-arm-fat-ratio-male | ETC | Andersen | 2019 | NA | 116138 | 2 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 4.17e-10 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 7.34e-10 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 3.65e-7 |
Osteoarthritis | Osteoarthritis | ETC | Tachmazidou | 2019 | 77052 | 378169 | 3 | VentoTormo_2018_decidua_monocyte: p = 3.79e-8 Braga_2020_lung_Alveolar cells type 1: p = 2.87e-6 Madissoon_2020_lung_DC Monocyte Dividing: p = 7.82e-6 |
Osteoarthritis | Osteoarthritis of the hip or knee | ETC | Tachmazidou | 2019 | 39427 | 378169 | 3 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 7.25e-8 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 1.14e-7 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 2.77e-7 |
Osteoarthritis | Osteoarthritis hip | ETC | Tachmazidou | 2019 | 15704 | 378169 | 3 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 2.30e-9 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 3.41e-6 VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 8.48e-6 |
Osteoarthritis | Knee osteoarthritis | ETC | Tachmazidou | 2019 | 24955 | 376169 | 3 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 4.41e-10 Madissoon_2020_lung_T cells Dividing: p = 7.89e-9 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 9.56e-9 |
Brain volume | White matter hyperintensity volume | ETC | Traylor | 2019 | NA | 8429 | 3 | Madissoon_2020_lung_DC activated: p = 1.49e-6 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 6.37e-6 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 3.19e-5 |
Smoking | Smoking initiation ever regular vs never-regular | ETC | Liua | 2019 | NA | 1232091 | 2 | Lake_2017_VisualCortex_Excitatory neuron 3a: p = 8.51e-17 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 2.21e-12 Lake_2017_VisualCortex_Excitatory neuron 1: p = 4.13e-12 |
Alcohol consumption | Alcohol consumption, drinks-per-week | ETC | Liua | 2019 | NA | 941280 | 3 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.85e-15 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 3.52e-11 Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.57e-9 |
Smoking | Smoking cessation | ETC | Liua | 2019 | NA | 547219 | 4 | Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 1.07e-6 Enge_2017_Pancreas_pancreatic A cell: p = 5.55e-6 Lake_2017_CerebellarHemisphere_Granule cell: p = 2.13e-5 |
Smoking | Smoking behaviour, cigarettes smoked per day | ETC | Liua | 2019 | NA | 377334 | 3 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 2.05e-8 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 3.75e-6 Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.41e-5 |
Smoking | Age of smoking initiation | ETC | Liua | 2019 | NA | 341427 | 3 | Lake_2017_VisualCortex_Excitatory neuron 3a: p = 5.17e-8 Lake_2017_VisualCortex_Excitatory neuron 1: p = 2.65e-7 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.92e-6 |
Depression | Depressive-symptoms | ETC | Baselmans | 2019 | NA | 1067913 | 3 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 6.16e-14 Lake_2017_VisualCortex_Excitatory neuron 3a: p = 2.64e-11 Lake_2017_FrontalCortex_Excitatory neuron 1: p = 5.11e-11 |
Neuroticism | Neuroticism | ETC | Baselmans | 2019 | NA | 523783 | 3 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 4.41e-17 Lake_2017_VisualCortex_Excitatory neuron 3a: p = 1.02e-16 Lake_2017_FrontalCortex_Excitatory neuron 1: p = 1.14e-15 |
Positive affect | Positive affect | ETC | Baselmans | 2019 | NA | 410603 | 4 | Lake_2017_FrontalCortex_Excitatory neuron 4: p = 2.03e-6 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 3.41e-6 Lake_2017_VisualCortex_Excitatory neuron 4: p = 6.60e-6 |
Life satisfaction | Life satisfaction | ETC | Baselmans | 2019 | NA | 80852 | 5 | Madissoon_2020_spleen_NK dividing: p = 9.96e-6 Madissoon_2020_lung_Plasma cells: p = 4.12e-5 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 7.85e-5 |
Body fat | Body fat percentage | ETC | Hubel | 2018 | 70700 | 85261 | 2 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 9.56e-13 Lake_2017_FrontalCortex_Excitatory neuron 5b: p = 4.65e-12 Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.21e-10 |
Postburn scar height | Postburn scar height | ETC | Wallace | 2018 | NA | 665 | 2 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 1.80e-4 Segerstolpe_2016_PancreaticIslets_pancreatic ductal cell: p = 4.39e-4 Madissoon_2020_lung_Blood vessel: p = 5.57e-4 |
Postburn scar pliability | Postburn scar pliability | ETC | Wallace | 2018 | NA | 665 | 1 | VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 3.67e-4 FetalFemaleGonad_Fetal epithelial progenitor: p = 5.54e-4 Lake_2017_FrontalCortex_Inhibitory neuron 1c: p = 6.09e-4 |
Erectile dysfunction | Erectile dysfunction | ETC | Bovijn | 2018 | 6175 | 217630 | 2 | FetalKidney_Fetal epithelial progenitor: p = 3.05e-6 AdultTransverseColon_Mast cell: p = 6.70e-5 Madissoon_2020_oesophagus_Mast cell: p = 1.37e-4 |
Psoriatic arthritis | Psoriatic arthritis | ETC | Aterido | 2018 | 744 | 1454 | 2 | Lake_2017_VisualCortex_Microglia: p = 1.56e-7 AdultTemporalLobe_Macrophage: p = 3.34e-7 FetalMuscle_Dendritic cell: p = 3.49e-7 |
Asthma | Asthma, moderate or severe | ETC | Shrine | 2018 | 5414 | 21471 | 4 | FetalLiver_Dendritic cell: p = 1.04e-10 Madissoon_2020_oesophagus_B CD27pos: p = 3.38e-10 Madissoon_2020_oesophagus_B CD27neg: p = 6.40e-10 |
Sleep | Sleep duration | ETC | Doherty | 2018 | NA | 91105 | 3 | Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.63e-8 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 1.63e-8 Lake_2017_VisualCortex_Excitatory neuron 1: p = 4.93e-8 |
Physical activity | Physical activity, overall physical activity time | ETC | Doherty | 2018 | NA | 91105 | 3 | Lake_2017_VisualCortex_Excitatory neuron 4: p = 2.64e-14 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 5.35e-14 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 1.64e-12 |
Sedentary behaviour duration | Sedentary behaviour duration | ETC | Doherty | 2018 | NA | 91105 | 3 | Lake_2017_VisualCortex_Excitatory neuron 5a: p = 4.09e-8 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.24e-7 Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.24e-7 |
Physical activity | Physical activity, walking duration | ETC | Doherty | 2018 | NA | 91105 | 2 | Lake_2017_VisualCortex_Excitatory neuron 5a: p = 6.15e-12 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 8.99e-8 Lake_2017_VisualCortex_Excitatory neuron 4: p = 5.36e-7 |
Physical activity | Physical activity, moderate intensity activity duration | ETC | Doherty | 2018 | NA | 91105 | 3 | Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.05e-8 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 1.58e-6 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 6.29e-6 |
Nonischemic cardiomyopathy | Nonischemic cardiomyopathy | ETC | Aragam | 2018 | 1816 | 388326 | 2 | FetalSkin_Smooth muscle cell: p = 8.55e-6 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 8.93e-6 AdultThyroid_Endothelial cell: p = 1.21e-4 |
Heart failure | Heart failure | ETC | Aragam | 2018 | 6504 | 387652 | 2 | VentoTormo_2018_decidua_decidual macrophage (dM1): p = 8.61e-6 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.46e-5 Madissoon_2020_lung_Macrophage MARCOneg: p = 1.59e-4 |
Hippocampal volume | Hippocampal tail volume | ETC | Meer | 2018 | NA | 21297 | 2 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 1.30e-4 Madissoon_2020_lung_NK Dividing: p = 3.18e-4 Madissoon_2020_spleen_NK dividing: p = 3.82e-4 |
Fimbria volume | Fimbria volume | ETC | Meer | 2018 | NA | 21297 | 2 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 5.72e-5 Lake_2017_VisualCortex_Excitatory neuron 1: p = 3.49e-4 VentoTormo_2018_decidua_decidual macrophage (dM1): p = 5.47e-4 |
Parasubiculum volume | Parasubiculum volume | ETC | Meer | 2018 | NA | 21297 | 3 | Madissoon_2020_lung_Lymph vessel: p = 6.68e-4 MacParland_2018_liver_Erythroid cell: p = 1.76e-3 Lake_2017_VisualCortex_Excitatory neuron 4: p = 3.08e-3 |
Hippocampal volume | Hippocampal fissure volume | ETC | Meer | 2018 | NA | 21297 | 1 | Madissoon_2020_lung_DC 1: p = 1.98e-3 Madissoon_2020_spleen_T cell dividing: p = 3.36e-3 FetalCalvaria_Erythroid cell: p = 3.39e-3 |
Brain volume | Dentate gyrus molecular layer volume | ETC | Meer | 2018 | NA | 21297 | 2 | VentoTormo_2018_decidua_decidual macrophage (dM1): p = 4.79e-7 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 7.28e-6 VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 8.49e-5 |
Brain volume | Dentate gyrus granule cell layer volume | ETC | Meer | 2018 | NA | 21297 | 2 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 7.45e-5 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 1.27e-4 Braga_2020_lung_B cell: p = 4.83e-4 |
Hippocampal volume | Hippocampal subfield CA4 volume | ETC | Meer | 2018 | NA | 21297 | 2 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 7.83e-4 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 2.12e-3 AdultTransverseColon_Macrophage: p = 2.71e-3 |
Hippocampal volume | Total hippocampal volume | ETC | Meer | 2018 | NA | 21297 | 3 | Lake_2017_VisualCortex_Excitatory neuron 5a: p = 1.94e-4 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 2.58e-4 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 3.85e-4 |
Hippocampal volume | Hippocampal subfield CA1 volume | ETC | Meer | 2018 | NA | 21297 | 2 | VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 4.40e-7 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 5.61e-6 Lake_2017_VisualCortex_Excitatory neuron 3d: p = 2.24e-5 |
Subiculum volume | Subiculum volume | ETC | Meer | 2018 | NA | 21297 | 2 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 5.12e-4 VentoTormo_2018_decidua_conventional dendritic cell (DC1): p = 1.35e-3 Lake_2017_FrontalCortex_Inhibitory neuron 8: p = 1.41e-3 |
Presubiculum volume | Presubiculum volume | ETC | Meer | 2018 | NA | 21297 | 2 | Lake_2017_VisualCortex_Oligodendrocyte: p = 3.96e-5 Lake_2017_CerebellarHemisphere_Oligodendrocyte: p = 1.63e-4 VentoTormo_2018_decidua_monocyte: p = 2.29e-4 |
HATA volume | HATA volume corrected for total hippocampal volume | ETC | Meer | 2018 | NA | 21297 | 2 | Lake_2017_VisualCortex_Excitatory neuron 3d: p = 3.77e-4 NeonatalAdrenalGland_Erythroid cell: p = 1.93e-3 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 3.24e-3 |
Fimbria volume | Fimbria volume corrected for total hippocampal volume | ETC | Meer | 2018 | NA | 21297 | 1 | VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 4.79e-4 FetalMaleGonad_Endothelial cell: p = 1.36e-3 Lake_2017_VisualCortex_Excitatory neuron 1: p = 1.69e-3 |
Hippocampal volume | Hippocampal tail volume, corrected for total hippocampal volume | ETC | Meer | 2018 | NA | 21297 | 2 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 8.27e-7 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 6.10e-5 FetalStomach_Smooth muscle cell: p = 2.63e-4 |
Hippocampal volume | Hippocampal fissure volume, corrected for total hippocampal volume | ETC | Meer | 2018 | NA | 21297 | 2 | VentoTormo_2018_decidua_glandular epithelial cell (Epi2): p = 1.90e-4 Madissoon_2020_oesophagus_Epi suprabasal: p = 3.50e-4 Lake_2017_VisualCortex_Excitatory neuron 6b: p = 9.53e-4 |
Brain volume | Dentate gyrus molecular layer volume, corrected for total hippocampal volume | ETC | Meer | 2018 | NA | 21297 | 2 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 4.47e-5 Madissoon_2020_lung_Muscle cells: p = 2.02e-4 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 5.44e-4 |
Brain volume | Dentate gyrus granule cell layer volume corrected for total hippocampal volume | ETC | Meer | 2018 | NA | 21297 | 2 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 9.42e-7 Lake_2017_VisualCortex_Excitatory neuron 3d: p = 1.91e-5 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 4.91e-5 |
Hippocampal volume | Hippocampal subfield CA4 volume, corrected for total hippocampal volume | ETC | Meer | 2018 | NA | 21297 | 2 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.21e-6 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 6.03e-5 Lake_2017_VisualCortex_Excitatory neuron 3d: p = 2.32e-4 |
Hippocampal volume | Hippocampal subfield CA3 volume, corrected for total hippocampal volume | ETC | Meer | 2018 | NA | 21297 | 2 | Madissoon_2020_oesophagus_Epi stratified: p = 3.85e-4 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 4.03e-4 Madissoon_2020_spleen_Plasmablast: p = 4.93e-4 |
Hippocampal volume | Hippocampal subfield CA1 volume, corrected for total hippocampal volume | ETC | Meer | 2018 | NA | 21297 | 3 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 2.50e-8 Madissoon_2020_lung_Macrophage MARCOpos: p = 6.56e-6 Lake_2017_VisualCortex_Excitatory neuron 3d: p = 2.60e-5 |
Subiculum volume | Subiculum volume, corrected for total hippocampal volume | ETC | Meer | 2018 | NA | 21297 | 3 | FetalThymus_CB CD34+: p = 1.69e-4 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 1.82e-4 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 3.07e-4 |
Parasubiculum volume | Presubiculum volume, corrected for total hippocampal volume | ETC | Meer | 2018 | NA | 21297 | 2 | VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 9.08e-4 AdultBoneMarrow_B cell (Plasmocyte): p = 1.83e-3 AdultBoneMarrow_T cell: p = 1.83e-3 |
HATA volume | Hippocampal amygdala transition area volume | ETC | Meer | 2018 | NA | 21297 | 2 | Madissoon_2020_spleen_CD34 progenitor: p = 7.70e-5 FetalRib_Fetal stromal cell: p = 2.01e-3 FetalKidney_Erythroid cell: p = 2.23e-3 |
Hippocampal volume | Hippocampal subfield CA3 volume | ETC | Meer | 2018 | NA | 21297 | 3 | FetalPancreas_Fetal neuron: p = 8.68e-5 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.17e-3 FetalIntestine_Endothelial cell: p = 2.18e-3 |
Parasubiculum volume | Parasubiculum volume, corrected for total hippocampal volume | ETC | Meer | 2018 | NA | 21297 | 2 | Lake_2017_VisualCortex_Inhibitory neuron 1a: p = 4.57e-3 FetalMaleGonad_Fetal mesenchymal progenitor: p = 7.35e-3 Voigt_2019_retina_2_Fibroblasts: p = 9.63e-3 |
IHPS | Infantile hypertrophic pyloric stenosis | ETC | Fadista | 2018 | NA | 4438 | 3 | VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 3.54e-11 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 1.38e-7 Lake_2017_VisualCortex_Excitatory neuron 1: p = 2.11e-7 |
ACR | Urinary albumin to creatinine ratio | ETC | Zanetti | 2019 | NA | 218759 | 3 | VentoTormo_2018_decidua_decidual macrophage (dM2): p = 5.07e-5 Lake_2017_FrontalCortex_Inhibitory neuron 1c: p = 6.09e-5 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 7.35e-5 |
Na/C | Urinary sodium to creatinine ratio | ETC | Zanetti | 2019 | NA | 218450 | 3 | VentoTormo_2018_decidua_monocyte: p = 3.27e-9 Lake_2017_VisualCortex_Excitatory neuron 1: p = 4.45e-8 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 5.47e-7 |
AUD | Alcohol-Use-Disorder | ETC | Kranzler | 2019 | 34658 | 167346 | 5 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.24e-8 Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 5.24e-6 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 8.56e-6 |
AUDIT-C | Alcohol-Use-Disorder-Identification-Test-Consumption | ETC | Kranzler | 2019 | NA | 200680 | 4 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.48e-8 Lake_2017_VisualCortex_Excitatory neuron 4: p = 4.43e-8 Lake_2017_VisualCortex_Excitatory neuron 3a: p = 1.59e-6 |
Medication use | Medication use (drugs for peptic ulcer and gastro-oesophageal reflux disease) | ETC | Wu Y | 2019 | 53,137 | 79,230 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 7.49e-10 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 6.55e-8 Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.85e-7 | |
Medication use | Medication use (drugs used in diabetes) | ETC | Wu Y | 2019 | 15,272 | 290,641 | VentoTormo_2018_decidua_decidual macrophage (dM1): p = 3.73e-7 Madissoon_2020_oesophagus_B CD27pos: p = 3.99e-7 Madissoon_2020_lung_DC 1: p = 8.86e-7 | |
Medication use | Medication use (antithrombotic agents) | ETC | Wu Y | 2019 | 67,653 | 85,986 | VentoTormo_2018_decidua_decidual macrophage (dM2): p = 6.14e-6 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 9.64e-6 Madissoon_2020_spleen_DC 1: p = 1.26e-5 | |
Medication use | Medication use (vasodilators used in cardiac diseases) | ETC | Wu Y | 2019 | 5,546 | 237,113 | VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 7.56e-6 Voigt_2019_retina_2_Choriocapillaris: p = 1.65e-5 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 8.44e-5 | |
Medication use | Medication use (antihypertensives) | ETC | Wu Y | 2019 | 6,431 | 145,949 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 5.02e-6 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 7.71e-6 Madissoon_2020_spleen_Monocyte: p = 1.11e-5 | |
Medication use | Medication use (beta blocking agents) | ETC | Wu Y | 2019 | 31,700 | 192,324 | VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 1.64e-8 VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 3.91e-7 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 1.24e-6 | |
Medication use | Medication use (diuretics) | ETC | Wu Y | 2019 | 34,453 | 194,633 | VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 1.37e-7 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.76e-7 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 3.61e-7 | |
Medication use | Medication use (calcium channel blockers) | ETC | Wu Y | 2019 | 31,904 | 172,474 | Lake_2017_VisualCortex_Endothelial cell: p = 2.75e-8 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 5.78e-8 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 9.63e-8 | |
Medication use | Medication use (agents acting on the renin-angiotensin system) | ETC | Wu Y | 2019 | 62,752 | 174,778 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 6.10e-9 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 3.11e-8 AdultKidney_Smooth muscle cell: p = 6.55e-8 | |
Medication use | Medication use (HMG CoA reductase inhibitors) | ETC | Wu Y | 2019 | 73,475 | 216,910 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 2.60e-10 VentoTormo_2018_decidua_decidual macrophage (dM1): p = 1.09e-7 Madissoon_2020_lung_Macrophage MARCOpos: p = 1.12e-7 | |
Medication use | Medication use (thyroid preparations) | ETC | Wu Y | 2019 | 24,832 | 280,750 | Madissoon_2020_oesophagus_T CD4: p = 1.67e-23 Madissoon_2020_lung_DC activated: p = 3.61e-21 Voigt_2019_retina_2_White blood cell 2: p = 6.07e-20 | |
Medication use | Medication use (immunosuppressants) | ETC | Wu Y | 2019 | 3,954 | 268,648 | Madissoon_2020_oesophagus_B CD27pos: p = 1.57e-17 Madissoon_2020_lung_DC 1: p = 6.60e-16 FetalFemaleGonad_Macrophage: p = 6.89e-14 | |
Medication use | Medication use (anti-inflammatory and antirheumatic products, non-steroids) | ETC | Wu Y | 2019 | 74,150 | 90,370 | FetalThymus_Dendritic cell: p = 2.62e-7 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 4.87e-7 FetalSpinalCord_Macrophage: p = 1.01e-6 | |
Medication use | Medication use (drugs affecting bone structure and mineralization) | ETC | Wu Y | 2019 | 7,870 | 207,798 | Madissoon_2020_oesophagus_B CD27pos: p = 3.02e-10 Madissoon_2020_oesophagus_B CD27neg: p = 3.02e-10 Segerstolpe_2016_PancreaticIslets_acinar cell: p = 7.41e-8 | |
Medication use | Medication use (opioids) | ETC | Wu Y | 2019 | 22,982 | 55,826 | VentoTormo_2018_decidua_conventional dendritic cell (DC1): p = 3.08e-7 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.04e-6 Madissoon_2020_lung_DC 1: p = 1.80e-6 | |
Medication use | Medication use (salicylic acid and derivatives) | ETC | Wu Y | 2019 | 61,583 | 50,427 | Madissoon_2020_lung_Macrophage Dividing: p = 1.68e-5 VentoTormo_2018_decidua_conventional dendritic cell (DC1): p = 2.62e-5 Madissoon_2020_spleen_Macrophage: p = 2.66e-5 | |
Medication use | Medication use (anilides) | ETC | Wu Y | 2019 | 83,218 | 96,592 | FetalThymus_Dendritic cell: p = 1.16e-7 AdultProstate_Endothelial cell (APC): p = 1.49e-7 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 2.71e-7 | |
Medication use | Medication use (antimigraine preparations) | ETC | Wu Y | 2019 | 5,521 | 114,323 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 4.69e-6 Madissoon_2020_lung_Blood vessel: p = 4.70e-6 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 6.15e-5 | |
Medication use | Medication use (antidepressants) | ETC | Wu Y | 2019 | 33,757 | 270,405 | Lake_2017_VisualCortex_Inhibitory neuron 1b: p = 3.06e-8 Lake_2017_FrontalCortex_Excitatory neuron 5b: p = 1.53e-7 Lake_2017_VisualCortex_Inhibitory neuron 4a: p = 2.76e-6 | |
Medication use | Medication use (adrenergics, inhalants) | ETC | Wu Y | 2019 | 28,880 | 147,565 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 2.12e-15 Voigt_2019_retina_2_White blood cell 2: p = 8.82e-13 Madissoon_2020_oesophagus_B CD27pos: p = 3.03e-12 | |
Medication use | Medication use (glucocorticoids) | ETC | Wu Y | 2019 | 17,352 | 188,348 | Madissoon_2020_oesophagus_B CD27pos: p = 1.37e-14 AdultRectum_B cell: p = 2.34e-14 Madissoon_2020_oesophagus_B CD27neg: p = 3.08e-13 | |
Medication use | Medication use (antihistamines for systemic use) | ETC | Wu Y | 2019 | 13,984 | 137,652 | Madissoon_2020_lung_DC 1: p = 3.91e-10 FetalLiver_Dendritic cell: p = 2.72e-9 FetalLiver_B cell: p = 2.72e-9 | |
Medication use | Medication use (antiglaucoma preparations and miotics) | ETC | Wu Y | 2019 | 5,215 | 95,653 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 4.54e-8 AdultKidney_Smooth muscle cell: p = 8.64e-7 Madissoon_2020_oesophagus_Fibroblast: p = 2.29e-6 | |
Varicose veins | Varicose veins | ETC | Shadrina AS | 2019 | 10,861 | 397,594 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 6.18e-8 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 2.83e-7 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 4.63e-7 | |
Glomerular filtration rate | Estimated glomerular filtration rate | ETC | Wuttke M | 2019 | NA | 567,460 | VentoTormo_2018_decidua_glandular epithelial cell (Epi2): p = 5.30e-10 Madissoon_2020_lung_Alveolar Type1: p = 1.96e-8 AdultKidney_Epithelial cell: p = 5.15e-8 | |
Blood urea nitrogen levels | Blood urea nitrogen levels | ETC | Wuttke M | 2019 | NA | 243,029 | FetalMaleGonad_Fetal epithelial progenitor: p = 8.56e-7 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 3.15e-6 Madissoon_2020_lung_Macrophage Dividing: p = 4.02e-6 | |
CKD | Chronic kidney disease | ETC | Wuttke M | 2019 | 64,164 | 561,055 | VentoTormo_2018_decidua_decidual macrophage (dM2): p = 2.16e-11 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 6.82e-11 Madissoon_2020_lung_Macrophage MARCOneg: p = 2.64e-10 | |
Diverticular disease | Diverticular disease | ETC | Schafmayer C | 2019 | 31,964 | 419,135 | VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 1.81e-12 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 5.69e-12 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 8.81e-9 | |
Renal cell carcinoma | Renal cell carcinoma female | ETC | Laskar RS | 2019 | 1,992 | 3,095 | Lake_2017_FrontalCortex_Excitatory neuron 5b: p = 2.77e-75 Lake_2017_VisualCortex_Excitatory neuron 1: p = 2.69e-71 Lake_2017_VisualCortex_Excitatory neuron 6b: p = 2.51e-67 | |
Renal cell carcinoma | Renal cell carcinoma male | ETC | Laskar RS | 2019 | 3,227 | 4,916 | Lake_2017_FrontalCortex_Excitatory neuron 5b: p = 7.42e-104 Lake_2017_VisualCortex_Excitatory neuron 1: p = 1.06e-86 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 1.06e-86 | |
Periodontal disease | Periodontal disease related phenotype (PCT2) | ETC | Offenbacher S | 2016 | NA | 975 | AdultTrachea_Endothelial cell: p = 3.49e-6 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 4.84e-6 VentoTormo_2018_decidua_monocyte: p = 3.11e-5 | |
Periodontal disease | Periodontal disease related phenotype (PCT3) | ETC | Offenbacher S | 2016 | NA | 975 | Voigt_2019_retina_2_White blood cell 2: p = 7.15e-4 Madissoon_2020_spleen_NK FCGR3Apos: p = 8.96e-4 Madissoon_2020_oesophagus_T CD4: p = 9.94e-4 | |
Periodontal disease | Periodontal disease related phenotype (PCT4) | ETC | Offenbacher S | 2016 | NA | 975 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 3.79e-9 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 8.63e-8 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 3.76e-7 | |
Periodontal disease | Periodontal disease related phenotype (PCT5) | ETC | Offenbacher S | 2016 | NA | 975 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 2.22e-5 Enge_2017_Pancreas_pancreatic A cell: p = 1.25e-4 Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.45e-4 | |
Periodontal disease | Periodontal disease related phenotype (PCT6) | ETC | Offenbacher S | 2016 | NA | 975 | Lake_2017_VisualCortex_Excitatory neuron 3a: p = 2.85e-6 Lake_2017_VisualCortex_Excitatory neuron 1: p = 5.55e-6 Voigt_2019_retina_2_Choriocapillaris: p = 2.79e-5 | |
Nonalcoholic Liver disease | Nonalcoholic fatty liver disease | ETC | Namjou B | 2019 | 1,106 | 8,571 | Madissoon_2020_lung_Macrophage MARCOpos: p = 9.25e-5 VentoTormo_2018_decidua_decidual macrophage (dM1): p = 1.18e-3 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.21e-3 | |
Nonalcoholic Liver disease | Liver fibrosis in non-alcoholic fatty acid liver disease | ETC | Namjou B | 2019 | NA | 235 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 1.45e-6 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 4.77e-5 Lake_2017_VisualCortex_Excitatory neuron 1: p = 9.27e-5 | |
Nonalcoholic Liver disease | Non-alcoholic fatty liver disease activity score | ETC | Namjou B | 2019 | NA | 235 | AdultLiver_Sinusoidal endothelial cell: p = 3.32e-5 Lake_2017_VisualCortex_Inhibitory neuron 8: p = 1.41e-4 FetalMuscle_Macrophage: p = 2.02e-4 | |
Autistic traits score | Autistic traits score (Social and Communication Disorders Checklist) | ETC | Massrali A | 2019 | NA | 5,628 | Lake_2017_VisualCortex_Excitatory neuron 3a: p = 8.58e-5 Madissoon_2020_lung_DC activated: p = 9.79e-5 VentoTormo_2018_decidua_innate lymphoid cell (ILC3): p = 2.64e-4 | |
Stress sensitivity | Stress sensitivity (neuroticism score x major depressive disorder status interaction) | ETC | Arnau-Soler A | 2018 | 2,010 | 5,145 | AdultKidney_Macrophage: p = 2.29e-5 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 3.08e-5 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 9.94e-5 | |
Stress sensitivity | Stress sensitivity (neuroticism score x major depressive disorder status interaction) | ETC | Arnau-Soler A | 2018 | 7,834 | 15,258 | AdultAdrenalGland_Myeloid cell: p = 6.21e-6 Madissoon_2020_spleen_T CD4 reg: p = 3.36e-5 FetalAdrenalGland_Fetal epithelial progenitor: p = 1.17e-4 | |
Stress sensitivity | Stress sensitivity (neuroticism score x major depressive disorder status interaction) | ETC | Arnau-Soler A | 2018 | 9,844 | 20,403 | Lake_2017_VisualCortex_Microglia: p = 2.63e-5 Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 4.23e-5 Madissoon_2020_spleen_NK FCGR3Apos: p = 4.53e-5 | |
Multisite chronic pain | Multisite chronic pain | ETC | Johnston KJA | 2019 | NA | 387,649 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 4.68e-12 Lake_2017_VisualCortex_Excitatory neuron 3a: p = 1.18e-9 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 2.10e-9 | |
Longevity | Longevity (age >90th survival percentile) | ETC | Deelen J | 2019 | 11,262 | 25,483 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 5.60e-7 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 9.60e-6 Madissoon_2020_spleen_Macrophage: p = 2.53e-5 | |
Longevity | Longevity (age >99th survival percentile) | ETC | Deelen J | 2019 | 3,484 | 25,483 | CordBloodCD34P_Monocyte: p = 2.73e-4 Madissoon_2020_lung_DC 2: p = 3.62e-4 AdultKidney_Epithelial cell: p = 6.22e-4 | |
Urinary sodium excretion | Urinary sodium excretion | ETC | Pazoki R | 2019 | NA | 446,237 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 5.17e-12 Lake_2017_VisualCortex_Excitatory neuron 3a: p = 1.84e-11 Lake_2017_FrontalCortex_Excitatory neuron 5b: p = 3.62e-8 | |
Urinary potassium excretion | Urinary potassium excretion | ETC | Pazoki R | 2019 | NA | 446,230 | Lake_2017_VisualCortex_Excitatory neuron 5a: p = 4.68e-13 Lake_2017_VisualCortex_Excitatory neuron 3a: p = 5.17e-11 Lake_2017_FrontalCortex_Excitatory neuron 5b: p = 3.75e-10 | |
same-sex sexual behaviour | same-sex sexual behaviour Male | ETC | Ganna A | 2019 | NA | 188,825 | Enge_2017_Pancreas_pancreatic D cell: p = 1.91e-7 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 2.98e-7 VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 2.98e-7 | |
same-sex sexual behaviour | same-sex sexual behaviour Female | ETC | Ganna A | 2019 | NA | 220,170 | Madissoon_2020_oesophagus_Endothelia vascular venous: p = 7.05e-6 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 4.04e-5 Madissoon_2020_lung_T cells Dividing: p = 1.15e-4 | |
same-sex sexual behaviour | same-sex sexual behaviour | ETC | Ganna A | 2019 | NA | 408,995 | Lake_2017_VisualCortex_Excitatory neuron 3a: p = 3.21e-7 Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 2.05e-6 Enge_2017_Pancreas_pancreatic D cell: p = 3.48e-6 | |
Knee pain | Knee pain | ETC | Meng W | 2019 | 22,204 | 149,312 | Lake_2017_VisualCortex_Excitatory neuron 5a: p = 1.75e-5 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 8.16e-5 FetalIntestine_Smooth muscle cell: p = 9.35e-4 | |
Occipital lobe volume | Occipital lobe volume | ETC | van der Lee SJ | 2019 | NA | 15,269 | FetalCalvaria_Fetal mesenchymal progenitor: p = 3.57e-5 Madissoon_2020_lung_Plasma cells: p = 1.26e-4 FetalRib_Fetal stromal cell: p = 2.01e-4 | |
Parietal lobe volume | Parietal lobe volume | ETC | van der Lee SJ | 2019 | NA | 15,269 | VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 5.85e-6 CordBloodCD34P_Neutrophil (RPS high): p = 7.12e-5 Madissoon_2020_spleen_ILC: p = 8.41e-5 | |
Temporal lobe volume | Temporal lobe volume | ETC | van der Lee SJ | 2019 | NA | 15,269 | Madissoon_2020_lung_Muscle cells: p = 6.06e-5 FetalIntestine_Fetal neuron: p = 1.42e-4 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.95e-4 | |
Frontal lobe volume | Frontal lobe volume | ETC | van der Lee SJ | 2019 | NA | 15,269 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 6.15e-7 Madissoon_2020_lung_DC Monocyte Dividing: p = 2.41e-4 Madissoon_2020_lung_NK Dividing: p = 3.79e-4 | |
Visceral adipose tissue | Predicted visceral adipose tissue Female | ETC | Karlsson T | 2019 | NA | 161,168 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 5.36e-20 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 5.81e-14 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 4.18e-13 | |
Visceral adipose tissue | Predicted visceral adipose tissue Male | ETC | Karlsson T | 2019 | NA | 163,984 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 1.16e-17 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 1.03e-16 Lake_2017_VisualCortex_Excitatory neuron 3a: p = 4.25e-16 | |
Visceral adipose tissue | Predicted visceral adipose tissue Both | ETC | Karlsson T | 2019 | NA | 325,153 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 1.75e-23 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 1.50e-16 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 3.55e-16 | |
Birth | Gestational age at birth (child effect) | ETC | Liu X | 2019 | NA | 84,689 | VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 1.66e-5 Madissoon_2020_lung_Alveolar Type1: p = 9.74e-5 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 1.04e-4 | |
Birth | Post-term birth | ETC | Liu X | 2019 | 7,888 | 60,148 | VentoTormo_2018_decidua_glandular epithelial cell (Epi2): p = 3.20e-4 Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 1.79e-3 AdultUterus_Macrophage: p = 1.83e-3 | |
Birth | Early spontaneous preterm birth | ETC | Liu X | 2019 | 1,139 | 60,148 | Enge_2017_Pancreas_pancreatic ductal cell: p = 3.54e-5 Lake_2017_VisualCortex_Excitatory neuron 1: p = 7.45e-5 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.33e-4 | |
Birth | Spontaneous preterm birth (preterm birth) | ETC | Liu X | 2019 | 4,775 | 60,148 | AdultPleura_Neutrophil: p = 6.05e-6 VentoTormo_2018_decidua_monocyte: p = 2.01e-5 Madissoon_2020_oesophagus_Dendritic Cells: p = 4.57e-5 | |
Alcohol consumption | Alcohol consumption | ETC | Evangelou E | 2019 | NA | 480,842 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.53e-16 Lake_2017_VisualCortex_Excitatory neuron 4: p = 4.01e-14 Lake_2017_VisualCortex_Excitatory neuron 1: p = 4.18e-11 | |
Albumin to creatinine ratio | Urinary albumin-to-creatinine ratio | ETC | Teumer A | 2019 | NA | 547,361 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 4.81e-7 Madissoon_2020_spleen_Macrophage: p = 6.72e-6 Madissoon_2020_lung_Macrophage MARCOpos: p = 8.34e-6 | |
Asthma | Asthma | ETC | Zhu Z | 2019 | 46,802 | 347,481 | Madissoon_2020_oesophagus_T CD4: p = 2.03e-18 Madissoon_2020_spleen_T CD4 reg: p = 1.63e-13 Madissoon_2020_spleen_T CD8 MAIT: p = 3.54e-13 | |
Asthma | Asthma (childhood onset) | ETC | Zhu Z | 2019 | 9,676 | 347,481 | VentoTormo_2018_decidua_decidual macrophage (dM2): p = 5.18e-13 VentoTormo_2018_decidua_plasmacytoid dendritic cell (DC2): p = 1.77e-12 VentoTormo_2018_decidua_monocyte: p = 3.73e-12 | |
Asthma | Asthma (adult onset) | ETC | Zhu Z | 2019 | 22,296 | 347,481 | Madissoon_2020_lung_DC 1: p = 1.45e-10 VentoTormo_2018_decidua_monocyte: p = 1.67e-8 Madissoon_2020_oesophagus_T CD4: p = 1.11e-7 | |
Urate | Urate levels | ETC | Tin A | 2019 | NA | 288,649 | Madissoon_2020_spleen_NK dividing: p = 1.27e-8 Madissoon_2020_lung_Plasma cells: p = 4.02e-8 Madissoon_2020_lung_Alveolar Type2: p = 2.86e-7 | |
Waist to hip ratio | Waist-to-hip ratio adjusted for BMI | ETC | Pulit SL | 2019 | NA | 379,501 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 4.06e-21 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 6.62e-19 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 1.34e-18 | |
Waist to hip ratio | Waist-to-hip ratio adjusted for BMI | ETC | Pulit SL | 2019 | NA | 315,284 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 2.25e-16 VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 3.19e-15 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 1.43e-13 | |
Waist to hip ratio | Waist-hip ratio | ETC | Pulit SL | 2019 | NA | 697,734 | VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 1.82e-16 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 1.03e-13 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 1.11e-12 | |
Waist to hip ratio | Waist-hip ratio | ETC | Pulit SL | 2019 | NA | 381,152 | VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 1.02e-13 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 1.90e-13 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 3.50e-13 | |
Waist to hip ratio | Waist-hip ratio | ETC | Pulit SL | 2019 | NA | 316,772 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 3.07e-12 Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 5.64e-11 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 5.72e-11 | |
Waist to hip ratio | Waist-to-hip ratio adjusted for BMI | ETC | Pulit SL | 2019 | NA | 694,649 | VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 2.94e-19 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 6.07e-19 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 1.24e-18 | |
BMI | Body mass index | ETC | Pulit SL | 2019 | NA | 374,756 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 4.59e-17 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 4.59e-17 Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.88e-16 | |
Joint damage | Joint damage in rheumatoid arthritis | ETC | Traylor M | 2019 | NA | 2,527 | FetalIntestine_Dendritic cell: p = 1.90e-7 Madissoon_2020_lung_DC activated: p = 3.39e-6 VentoTormo_2018_decidua_decidual macrophage (dM1): p = 4.12e-6 | |
BMI | Body mass index | ETC | Pulit SL | 2019 | NA | 434,794 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 3.78e-14 Lake_2017_VisualCortex_Excitatory neuron 4: p = 3.78e-14 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 3.78e-14 | |
AD | Alzheimer's disease | ETC | Moreno-Grau S | 2019 | 4,120 | 3,289 | VentoTormo_2018_decidua_decidual macrophage (dM2): p = 6.71e-6 VentoTormo_2018_decidua_decidual macrophage (dM1): p = 3.73e-5 Lake_2017_VisualCortex_Inhibitory neuron 3: p = 8.23e-5 | |
Body fat percentage | Body fat percentage variance | ETC | Wang H | 2019 | NA | 341,632 | AdultProstate_Endothelial cell (APC): p = 1.50e-9 AdultTemporalLobe_Macrophage: p = 1.47e-6 Lake_2017_VisualCortex_Microglia: p = 4.27e-6 | |
Basal metabolic rate | Basal metabolic rate variance | ETC | Wang H | 2019 | NA | 341,584 | AdultEsophagus_B cell (Plasmocyte): p = 4.17e-6 Madissoon_2020_lung_Plasma cells: p = 6.36e-6 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 1.09e-5 | |
BMI | Body mass index variance | ETC | Wang H | 2019 | NA | 346,393 | FetalThymus_Dendritic cell: p = 9.49e-8 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 5.33e-7 AdultProstate_Endothelial cell (APC): p = 5.70e-7 | |
Waist circumference | Waist circumference variance | ETC | Wang H | 2019 | NA | 347,158 | Madissoon_2020_lung_DC 1: p = 1.72e-8 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.41e-7 FetalFemaleGonad_Dendritic cell: p = 7.69e-6 | |
Hip circumference | Hip circumference variance | ETC | Wang H | 2019 | NA | 346,781 | Madissoon_2020_lung_DC 1: p = 3.79e-6 AdultProstate_Endothelial cell (APC): p = 4.81e-6 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 7.06e-6 | |
Waist to hip ratio | Waist-hip ratio variance | ETC | Wang H | 2019 | NA | 347,134 | Lake_2017_VisualCortex_Excitatory neuron 4: p = 5.92e-5 Lake_2017_VisualCortex_Excitatory neuron 6b: p = 5.92e-5 Lake_2017_FrontalCortex_Excitatory neuron 6b: p = 1.07e-4 | |
Height | Height variance | ETC | Wang H | 2019 | NA | 347,086 | VentoTormo_2018_decidua_decidual macrophage (dM1): p = 1.28e-6 Madissoon_2020_lung_Macrophage MARCOneg: p = 1.16e-5 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 2.13e-5 | |
Lung function | Lung function (forced vital capacity) variance | ETC | Wang H | 2019 | NA | 317,222 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 1.73e-6 Madissoon_2020_lung_DC 1: p = 5.60e-5 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.87e-4 | |
Lung function | Lung function (FEV1) variance | ETC | Wang H | 2019 | NA | 317,285 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 2.39e-4 FetalAdrenalGland_Erythroid cell: p = 6.62e-4 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 9.01e-4 | |
Lung function | Lung function (FEV1/FVC) variance | ETC | Wang H | 2019 | NA | 316,614 | Madissoon_2020_lung_B cell mature: p = 1.39e-6 VentoTormo_2018_decidua_monocyte: p = 1.78e-5 Madissoon_2020_lung_B cell naive: p = 4.02e-5 | |
Heel bone mineral Density | Heel bone mineral density variance | ETC | Wang H | 2019 | NA | 197,261 | Madissoon_2020_lung_DC Monocyte Dividing: p = 2.65e-5 VentoTormo_2018_decidua_decidual macrophage (dM1): p = 5.92e-5 FetalMuscle_Fetal stromal cell: p = 6.02e-5 | |
Birth weight | Birth weight variance | ETC | Wang H | 2019 | NA | 197,758 | Madissoon_2020_oesophagus_Dendritic Cells: p = 3.11e-5 Madissoon_2020_lung_Macrophage Dividing: p = 5.93e-5 Madissoon_2020_lung_Alveolar Type1: p = 9.96e-5 | |
Waist to hip ratio | BMI-adjusted waist-hip ratio variance | ETC | Wang H | 2019 | NA | 346,535 | Madissoon_2020_lung_B cell naive: p = 5.19e-7 Madissoon_2020_lung_B cell mature: p = 6.48e-6 Madissoon_2020_lung_Macrophage MARCOpos: p = 1.33e-5 | |
Systemic sclerosis | Systemic sclerosis | ETC | Lopez-Isac E | 2019 | 9,095 | 17,584 | Madissoon_2020_oesophagus_B CD27pos: p = 2.98e-12 AdultRectum_B cell: p = 2.99e-12 FetalLiver_Dendritic cell: p = 3.81e-12 | |
Macular degeneration | Disease progression in age-related macular degeneration (adjusted for baseline) | ETC | Yan Q | 2018 | NA | 2,721 | Madissoon_2020_lung_Fibroblast: p = 2.03e-7 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 3.69e-7 Madissoon_2020_oesophagus_Fibroblast: p = 8.16e-7 | |
Uterine fibroids and heavy menstrual bleeding | Uterine fibroids and heavy menstrual bleeding | ETC | Gallagher CS | 2019 | 3,409 | 199,171 | VentoTormo_2018_decidua_placental extravillous trophoblast cell (EVT): p = 1.40e-5 Lake_2017_VisualCortex_Endothelial cell: p = 5.30e-5 AdultLiver_Sinusoidal endothelial cell: p = 8.91e-5 | |
Heavy menstrual bleeding | Heavy menstrual bleeding | ETC | Gallagher CS | 2019 | 9,813 | 210,946 | Madissoon_2020_lung_NK Dividing: p = 2.01e-5 Madissoon_2020_lung_Secretory club: p = 1.47e-4 VentoTormo_2018_decidua_decidual macrophage (dM1): p = 2.57e-4 | |
Uterine fibroids | Uterine fibroids | ETC | Gallagher CS | 2019 | 20,406 | 223,918 | Madissoon_2020_oesophagus_Epi suprabasal: p = 4.60e-7 Madissoon_2020_spleen_T cell dividing: p = 1.23e-6 Madissoon_2020_lung_DC Monocyte Dividing: p = 6.42e-6 | |
Cytokine network | Cytokine network levels (multivariate analysis) | ETC | Nath AP | 2019 | NA | 9,263 | Madissoon_2020_spleen_CD34 progenitor: p = 6.16e-5 Madissoon_2020_spleen_NK dividing: p = 1.37e-4 VentoTormo_2018_decidua_decidual natural killer cell (dNK2): p = 1.43e-4 | |
Eosinophilic granulomatosis | Eosinophilic granulomatosis with polyangiitis (MPO-ANCA positive) | ETC | Lyons PA | 2019 | 159 | 6,688 | Madissoon_2020_lung_DC 1: p = 4.04e-14 VentoTormo_2018_decidua_conventional dendritic cell (DC1): p = 1.51e-12 FetalLiver_Dendritic cell: p = 6.51e-12 | |
Eosinophilic granulomatosis | Eosinophilic granulomatosis with polyangiitis (ANCA negative) | ETC | Lyons PA | 2019 | 352 | 6,688 | Madissoon_2020_lung_DC 1: p = 3.22e-8 FetalIntestine_Dendritic cell: p = 1.95e-7 Madissoon_2020_oesophagus_Dendritic Cells: p = 3.52e-7 | |
Eosinophilic granulomatosis | Eosinophilic granulomatosis with polyangiitis | ETC | Lyons PA | 2019 | 534 | 6,688 | Madissoon_2020_lung_DC activated: p = 5.58e-13 Madissoon_2020_oesophagus_B CD27neg: p = 5.60e-13 Madissoon_2020_lung_DC 1: p = 1.16e-11 | |
BMI at birth | BMI at birth | ETC | Helgeland O | 2019 | NA | 9,286 | Madissoon_2020_lung_Macrophage MARCOneg: p = 8.33e-8 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 8.26e-7 VentoTormo_2018_decidua_decidual macrophage (dM2): p = 2.57e-5 | |
BMI by age | BMI at 6 weeks old | ETC | Helgeland O | 2019 | NA | 6,450 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.52e-6 Madissoon_2020_lung_DC 1: p = 5.88e-6 Madissoon_2020_lung_DC 2: p = 6.51e-6 | |
BMI by age | BMI at 3 months old | ETC | Helgeland O | 2019 | NA | 7,970 | Madissoon_2020_lung_Alveolar Type1: p = 8.70e-7 VentoTormo_2018_decidua_glandular epithelial cell (Epi2): p = 2.47e-6 Madissoon_2020_spleen_T CD8 MAIT: p = 1.52e-4 | |
BMI by age | BMI at 6 months old | ETC | Helgeland O | 2019 | NA | 8,017 | Madissoon_2020_oesophagus_Glands duct: p = 3.47e-6 Voigt_2019_retina_2_Vein cell 2: p = 3.24e-5 Enge_2017_Pancreas_pancreatic A cell: p = 8.32e-5 | |
BMI by age | BMI at 8 months old | ETC | Helgeland O | 2019 | NA | 7,197 | Lake_2017_VisualCortex_Inhibitory neuron 8: p = 9.22e-5 FetalKidney_Fetal stromal cell: p = 2.74e-4 VentoTormo_2018_decidua_decidual natural killer cell (dNK1): p = 6.69e-4 | |
BMI by age | BMI at 1 year old | ETC | Helgeland O | 2019 | NA | 6,970 | Lake_2017_VisualCortex_Inhibitory neuron 8: p = 6.42e-4 AdultProstate_Basal cell: p = 8.84e-4 FetalMaleGonad_Fetal fibroblast: p = 1.11e-3 | |
BMI by age | BMI at 1.5 years old | ETC | Helgeland O | 2019 | NA | 6,800 | Madissoon_2020_spleen_B Hypermutation: p = 1.27e-4 Madissoon_2020_oesophagus_Epi suprabasal: p = 2.38e-4 AdultKidney_Endothelial cell: p = 2.47e-4 | |
BMI by age | BMI at 2 years old | ETC | Helgeland O | 2019 | NA | 4,631 | Madissoon_2020_oesophagus_Epi upper: p = 4.29e-5 VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 3.03e-4 AdultStomach_Fibroblast: p = 5.37e-4 | |
BMI by age | BMI at 3 years old | ETC | Helgeland O | 2019 | NA | 5,069 | AdultCerebellum_Smooth muscle cell: p = 3.84e-6 Enge_2017_Pancreas_mesenchymal cell: p = 5.74e-5 AdultThyroid_Stromal cell: p = 8.59e-5 | |
BMI by age | BMI at 5 years old | ETC | Helgeland O | 2019 | NA | 4,245 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 1.62e-8 AdultKidney_Smooth muscle cell: p = 4.59e-6 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 2.16e-5 | |
BMI by age | BMI at 7 years old | ETC | Helgeland O | 2019 | NA | 4,629 | Lake_2017_VisualCortex_Excitatory neuron 4: p = 7.32e-5 Lake_2017_VisualCortex_Inhibitory neuron 3: p = 7.32e-5 AdultBladder_Endothelial cell (APC): p = 9.79e-5 | |
BMI by age | BMI at 8 years old | ETC | Helgeland O | 2019 | NA | 3,862 | Madissoon_2020_lung_DC Monocyte Dividing: p = 3.71e-5 AdultEsophagus_Smooth muscle cell: p = 5.51e-5 FetalLung_Fetal stromal cell: p = 5.93e-5 | |
PD | Parkinson's disease in GBA mutation carriers | ETC | Blauwendraat C | 2020 | 1,588 | 7,584 | Madissoon_2020_spleen_DC plasmacytoid: p = 9.54e-6 FetalAdrenalGland_Fetal fibroblast: p = 2.78e-4 VentoTormo_2018_decidua_plasmacytoid dendritic cell (DC2): p = 4.19e-4 | |
PD | Parkinson's disease in GBA mutation carriers (age at onset) | ETC | Blauwendraat C | 2020 | NA | 1,353 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 8.08e-5 Lake_2017_VisualCortex_Microglia: p = 3.88e-4 Madissoon_2020_lung_Blood vessel: p = 6.45e-4 | |
Left ventricular | Left ventricular mass to end-diastolic volume ratio | ETC | Aung N | 2019 | NA | 16,884 | VentoTormo_2018_decidua_decidual macrophage (dM1): p = 4.85e-8 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 6.30e-7 Madissoon_2020_lung_Blood vessel: p = 8.45e-7 | |
Left ventricular | Left ventricular end-systolic volume | ETC | Aung N | 2019 | NA | 16,920 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 8.57e-7 Madissoon_2020_lung_Fibroblast: p = 1.02e-6 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 2.49e-6 | |
Left ventricular | Left ventricular ejection fraction | ETC | Aung N | 2019 | NA | 16,923 | VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 4.09e-5 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 1.42e-4 Madissoon_2020_lung_NK Dividing: p = 2.72e-4 | |
Left ventricular | Left ventricular mass | ETC | Aung N | 2019 | NA | 16,920 | VentoTormo_2018_decidua_proliferating decidual natural killer cell (dNK p): p = 1.52e-4 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 2.37e-4 Madissoon_2020_lung_Alveolar Type2: p = 3.97e-4 | |
Left ventricular | Left ventricular end-diastolic volume | ETC | Aung N | 2019 | NA | 16,920 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 2.55e-5 VentoTormo_2018_decidua_decidual macrophage (dM1): p = 4.10e-5 Madissoon_2020_spleen_DC 1: p = 6.56e-5 | |
Optic cup area | Optic cup area | ETC | Bonnemaijer PWM | 2019 | NA | 24,493 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 2.36e-14 Madissoon_2020_lung_Blood vessel: p = 1.60e-11 Madissoon_2020_lung_Lymph vessel: p = 5.04e-10 | |
Optic disc area | Optic disc area | ETC | Bonnemaijer PWM | 2019 | NA | 24,509 | VentoTormo_2018_decidua_placental extravillous trophoblast cell (EVT): p = 6.16e-6 Enge_2017_Pancreas_mesenchymal cell: p = 9.37e-6 VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 1.66e-5 | |
Vertical cup to disc ratio | Vertical cup-disc ratio | ETC | Bonnemaijer PWM | 2019 | NA | 25,180 | VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 4.69e-10 Voigt_2019_retina_2_Fibroblasts: p = 5.31e-10 VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 9.03e-10 | |
Intraocular pressure | Intraocular pressure | ETC | Bonnemaijer PWM | 2019 | NA | 31,269 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 2.30e-8 VentoTormo_2018_decidua_decidual perivascular cell (dP2): p = 9.04e-8 Lake_2017_VisualCortex_Pericytes: p = 1.46e-7 | |
Central corneal thickness | Central corneal thickness | ETC | Bonnemaijer PWM | 2019 | NA | 16,204 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 3.16e-8 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 3.38e-7 Madissoon_2020_lung_Fibroblast: p = 1.88e-6 | |
Temporale grey matter volume | Right planum temporale grey matter volume | ETC | Carrion-Castillo A | 2020 | NA | 18,039 | VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 2.36e-4 Enge_2017_Pancreas_pancreatic A cell: p = 3.60e-4 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 7.56e-4 | |
Temporale asymmetry | Planum temporale asymmetry index | ETC | Carrion-Castillo A | 2020 | NA | 18,049 | Madissoon_2020_spleen_DC plasmacytoid: p = 1.18e-3 AdultBoneMarrow_Erythroid cell: p = 1.37e-3 VentoTormo_2018_decidua_proliferating decidual natural killer cell (dNK p): p = 1.79e-3 | |
Temporale grey matter volume | Left planum temporale grey matter volume | ETC | Carrion-Castillo A | 2020 | NA | 18,037 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 1.49e-7 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 7.63e-7 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 1.29e-6 | |
Refractive error | Refractive error (age-at-onset of spectacle wearing-inferred) | ETC | Ghorbani Mojarrad N | 2020 | NA | 287,448 | Lake_2017_VisualCortex_Excitatory neuron 3a: p = 7.46e-11 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 3.18e-10 Lake_2017_VisualCortex_Excitatory neuron 4: p = 7.00e-10 | |
Refractive error | Refractive error (autorefraction measured) | ETC | Ghorbani Mojarrad N | 2020 | NA | 95,619 | Lake_2017_VisualCortex_Excitatory neuron 3a: p = 2.85e-7 Lake_2017_VisualCortex_Excitatory neuron 1: p = 1.73e-6 Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 1.73e-6 | |
Household income | Household income | ETC | Hill WD | 2019 | NA | 286,301 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 4.54e-10 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 4.54e-10 Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.01e-8 | |
Household income (MTAG) | Household income (MTAG) | ETC | Hill WD | 2019 | NA | 505,541 | Lake_2017_VisualCortex_Excitatory neuron 5a: p = 1.97e-13 Lake_2017_VisualCortex_Excitatory neuron 1: p = 3.82e-13 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 4.98e-12 | |
Heart failure | Heart failure | ETC | Shah S | 2020 | 47,309 | 930,014 | VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 4.37e-8 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 4.47e-6 Lake_2017_VisualCortex_Excitatory neuron 1: p = 1.45e-5 | |
CCL19 | CCL19 levels | ETC | Enroth S | 2014 | NA | 653 | FetalIntestine_CB CD34+: p = 3.01e-5 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 3.26e-5 FetalMaleGonad_Immature sertoli cell (Pre-Sertoli cell): p = 5.63e-5 | |
IL 6 | Interleukin-6 receptor subunit alpha levels | ETC | Enroth S | 2014 | NA | 653 | FetalMaleGonad_Immature sertoli cell (Pre-Sertoli cell): p = 5.45e-6 Madissoon_2020_lung_Blood vessel: p = 3.46e-5 Lake_2017_FrontalCortex_Inhibitory neuron 1c: p = 4.23e-5 | |
C-X-C chmokine | C-X-C motif chemokine 10 levels | ETC | Enroth S | 2014 | NA | 653 | FetalMaleGonad_Immature sertoli cell (Pre-Sertoli cell): p = 3.55e-5 FetalPancreas_Fetal neuron: p = 6.23e-5 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 6.52e-5 | |
CCL24 | CCL24 levels | ETC | Enroth S | 2014 | NA | 653 | Lake_2017_FrontalCortex_Inhibitory neuron 1c: p = 1.51e-6 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 2.27e-6 Lake_2017_VisualCortex_Inhibitory neuron 4b: p = 3.91e-6 | |
MHC class I | MHC class I polypeptide-related sequence A levels | ETC | Enroth S | 2014 | NA | 653 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 7.80e-10 Lake_2017_VisualCortex_Inhibitory neuron 4b: p = 6.06e-9 Madissoon_2020_lung_Macrophage MARCOneg: p = 6.50e-9 | |
CD40 | CD40 ligand levels | ETC | Enroth S | 2014 | NA | 653 | FetalMaleGonad_Immature sertoli cell (Pre-Sertoli cell): p = 3.72e-8 VentoTormo_2018_decidua_placental extravillous trophoblast cell (EVT): p = 1.51e-7 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 5.69e-7 | |
CXCL5 | CXCL5 levels | ETC | Enroth S | 2014 | NA | 653 | VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 1.46e-7 Enge_2017_Pancreas_pancreatic A cell: p = 4.75e-7 FetalMaleGonad_Immature sertoli cell (Pre-Sertoli cell): p = 1.46e-6 | |
Kallikrein11 | kallikrein-11 levels | ETC | Enroth S | 2014 | NA | 653 | Lake_2017_VisualCortex_Excitatory neuron 5a: p = 6.33e-6 Lake_2017_VisualCortex_Inhibitory neuron 1c: p = 4.20e-5 FetalMaleGonad_Immature sertoli cell (Pre-Sertoli cell): p = 4.49e-5 | |
Epithelial | epithelial cell adhesion molecule levels | ETC | Enroth S | 2014 | NA | 653 | Enge_2017_Pancreas_pancreatic A cell: p = 4.92e-6 Segerstolpe_2016_PancreaticIslets_pancreatic A cell: p = 1.53e-5 FetalMaleGonad_Immature sertoli cell (Pre-Sertoli cell): p = 5.63e-5 | |
IL 17 | interleukin 17 receptor B levels | ETC | Enroth S | 2014 | NA | 653 | FetalMaleGonad_Immature sertoli cell (Pre-Sertoli cell): p = 2.79e-5 Lake_2017_FrontalCortex_Inhibitory neuron 1c: p = 3.16e-5 FetalPancreas_Fetal endocrine cell: p = 6.18e-5 | |
IL 12 | interleukin 12 receptor subunit beta-1 levels | ETC | Enroth S | 2014 | NA | 653 | FetalMaleGonad_Immature sertoli cell (Pre-Sertoli cell): p = 2.17e-5 Enge_2017_Pancreas_pancreatic A cell: p = 1.01e-4 FetalAdrenalGland_Fasciculata cell: p = 1.16e-4 | |
Endothelial | vascular endothelial growth factor D levels | ETC | Enroth S | 2014 | NA | 653 | Lake_2017_VisualCortex_Inhibitory neuron 4b: p = 2.29e-10 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 1.37e-9 Lake_2017_VisualCortex_Inhibitory neuron 8: p = 1.14e-6 | |
E-selectin | E-selectin levels | ETC | Enroth S | 2014 | NA | 653 | Segerstolpe_2016_PancreaticIslets_pancreatic A cell: p = 1.30e-6 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 4.18e-6 FetalMaleGonad_Immature sertoli cell (Pre-Sertoli cell): p = 6.33e-6 | |
Melanoma | melanoma-derived growth regulatory protein levels | ETC | Enroth S | 2014 | NA | 653 | FetalMaleGonad_Immature sertoli cell (Pre-Sertoli cell): p = 3.52e-6 FetalHeart_Stromal cell: p = 2.30e-5 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 2.41e-5 | |
Metabolic syndrome | Metabolic syndrome | ETC | Lind L | 2019 | NA | 291,107 | VentoTormo_2018_decidua_Hofbauer cell (HB): p = 2.52e-9 Lake_2017_VisualCortex_Excitatory neuron 3c: p = 6.71e-8 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.82e-7 | |
Albumin to creatinine ratio | Urinary albumin-to-creatinine ratio | ETC | Casanova F | 2019 | NA | 437,027 | Voigt_2019_retina_2_Artery: p = 1.87e-6 VentoTormo_2018_decidua_Hofbauer cell (HB): p = 1.15e-5 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 1.76e-5 | |
Steroid sensitive nephrotic syndrome | Childhood steroid-sensitive nephrotic syndrome | ETC | Debiec H | 2018 | 132 | 2,000 | AdultRectum_B cell: p = 6.08e-6 AdultPeripheralBlood_B cell: p = 1.50e-5 AdultBoneMarrow_Dendritic cell: p = 3.30e-5 | |
Glaucoma (MTAG) | Glaucoma (multi-trait analysis) | ETC | Craig JE | 2020 | 119,318 | 232,378 | VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 2.18e-20 VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 3.13e-19 VentoTormo_2018_decidua_maternal endothelial cell (Endo m): p = 1.43e-18 | |
Snoring | Snoring main | ETC | Campos AI | 2020 | 152,302 | 256,015 | Lake_2017_VisualCortex_Excitatory neuron 5b: p = 3.58e-10 Lake_2017_VisualCortex_Excitatory neuron 3a: p = 1.26e-9 Lake_2017_VisualCortex_Excitatory neuron 4: p = 7.78e-8 | |
Snoring | Snoring adjusted BMI | ETC | Campos AI | 2020 | 151,836 | 255,230 | Lake_2017_VisualCortex_Excitatory neuron 5b: p = 8.10e-10 Lake_2017_VisualCortex_Excitatory neuron 3a: p = 6.25e-9 Lake_2017_VisualCortex_Excitatory neuron 4: p = 6.95e-8 | |
Snoring | Snoring male | ETC | Campos AI | 2020 | 90,806 | 99,165 | Lake_2017_VisualCortex_Excitatory neuron 4: p = 7.20e-9 VentoTormo_2018_decidua_decidual perivascular cell (dP1): p = 1.99e-8 Lake_2017_VisualCortex_Excitatory neuron 5a: p = 1.20e-7 | |
Snoring | Snoring Female | ETC | Campos AI | 2020 | 61,792 | 156,554 | Lake_2017_VisualCortex_Excitatory neuron 3b: p = 1.62e-6 Lake_2017_VisualCortex_Excitatory neuron 4: p = 1.62e-6 Lake_2017_VisualCortex_Excitatory neuron 5b: p = 6.04e-6 | |
Parental lifespan | Parental lifespan | ETC | Timmers PR | 2019 | NA | 500,193 | Lake_2017_VisualCortex_Excitatory neuron 1: p = 2.36e-10 Lake_2017_VisualCortex_Excitatory neuron 3b: p = 5.71e-9 Madissoon_2020_spleen_Plasmablast: p = 3.97e-8 | |
Retinal detachment | Retinal detachment or retinal break | ETC | Boutin TS | 2020 | 6148 | 59546 | VentoTormo_2018_decidua_decidual stromal cell (dS1): p = 2.50e-8 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 4.47e-8 Madissoon_2020_lung_Fibroblast: p = 3.77e-7 | |
COVID-19 Host Genetics | hospitalized covid vs. not hospitalized covid (EA) | ETC | covid19hg | 2020 | 928 | 2028 | Madissoon_2020_spleen_T CD8 MAIT: p = 1.35e-5 Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 3.76e-5 Madissoon_2020_oesophagus_Muscle: p = 4.52e-5 | |
COVID-19 Host Genetics | predicted covid from self-reported symptoms vs. predicted or self-reported non-covid (EA) | ETC | covid19hg | 2020 | 1865 | 29174 | Lake_2017_CerebellarHemisphere_Pericytes: p = 3.48e-6 VentoTormo_2018_decidua_decidual stromal cell (dS2): p = 9.19e-6 Madissoon_2020_oesophagus_Epi suprabasal: p = 7.67e-5 | |
COVID-19 | Severe COVID-19 infection with respiratory failure (analysis I) | ETC | Ellinghaus D | 2020 | 1610 | 2205 | FetalEyes_Fetal neuron: p = 1.44e-5 FetalSkin_Erythroid progenitor cell (RP high): p = 1.21e-4 Madissoon_2020_spleen_ILC: p = 1.56e-4 | |
COVID-19 | Severe COVID-19 infection with respiratory failure (analysis II) | ETC | Ellinghaus D | 2020 | 1610 | 2180 | Lake_2017_VisualCortex_Excitatory neuron 4: p = 4.86e-4 Lake_2017_VisualCortex_Inhibitory neuron 6b: p = 4.86e-4 Madissoon_2020_spleen_CD34 progenitor: p = 8.03e-4 | |
Alzheimer's disease (late onset) | late-onset Alzheimers disease | ETC | Kunkle BW | 2019 | 21982 | 41944 | VentoTormo_2018_decidua_decidual macrophage (dM1): p = 2.16e-12 FetalLiver_Macrophage: p = 3.64e-9 Madissoon_2020_lung_Macrophage MARCOpos: p = 5.57e-9 | |
COVID-19 | COVID-19 UKBB EUR tested (Mixed Population) | ETC | GRASP | 2020 | 1,291 | 5,455 | FetalLiver_Dendritic cell: p = 3.36e-6 Madissoon_2020_lung_Fibroblast: p = 9.82e-6 AdultKidney_Endothelial cell (APC): p = 2.09e-5 | |
COVID-19 | COVID-19 UKBB EUR (Mixed Population) | ETC | GRASP | 2020 | 1,291 | 457,959 | Madissoon_2020_lung_Fibroblast: p = 2.67e-4 VentoTormo_2018_decidua_decidual macrophage (dM1): p = 2.73e-4 Lake_2017_FrontalCortex_Excitatory neuron 3e: p = 4.03e-4 |
* If the number of cases is 0/NA, it means the phenotype is a continuous data type and the number of controls is the total number of samples.