| Tag | Content |
|---|---|
| Uniprot ID | O14793; A1C2J7; A1C2K0; Q6B0H2; |
| Entrez ID | 2660 |
| Genbank protein ID | AAH74757.2; ABI48421.1; AAB86694.1; AAC96327.1; ABI48419.1; ABI48422.1; |
| Genbank nucleotide ID | NM_005259.2 |
| Ensembl protein ID | ENSP00000260950 |
| Ensembl nucleotide ID | ENSG00000138379 |
| Gene name | Growth/differentiation factor 8 |
| Gene symbol | MSTN |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Acts specifically as a negative regulator of skeletal muscle growth. |
| Sequence | MQKLQLCVYI YLFMLIVAGP VDLNENSEQK ENVEKEGLCN ACTWRQNTKS SRIEAIKIQI 60 LSKLRLETAP NISKDVIRQL LPKAPPLREL IDQYDVQRDD SSDGSLEDDD YHATTETIIT 120 MPTESDFLMQ VDGKPKCCFF KFSSKIQYNK VVKAQLWIYL RPVETPTTVF VQILRLIKPM 180 KDGTRYTGIR SLKLDMNPGT GIWQSIDVKT VLQNWLKQPE SNLGIEIKAL DENGHDLAVT 240 FPGPGEDGLN PFLEVKVTDT PKRSRRDFGL DCDEHSTESR CCRYPLTVDF EAFGWDWIIA 300 PKRYKANYCS GECEFVFLQK YPHTHLVHQA NPRGSAGPCC TPTKMSPINM LYFNGKEQII 360 YGKIPAMVVD RCGCS 375 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.