Tag | Content |
---|---|
Uniprot ID | O96014; B2R8Z6; Q14DE8; Q8WZ98; |
Entrez ID | 7481 |
Genbank protein ID | BAB72099.1; CAA73223.1; AAH74791.1; AAH74790.1; AAI13387.1; AAI13389.1; BAG36343.1; CAA74159.1; |
Genbank nucleotide ID | NM_004626.2; XM_005274231.1; |
Ensembl protein ID | ENSP00000325526 |
Ensembl nucleotide ID | ENSG00000085741 |
Gene name | Protein Wnt-11 |
Gene symbol | WNT11 |
Organism | Homo sapiens |
NCBI taxa ID | 9606 |
Cleft type | |
Developmental stage | |
Data sources | Manually collected |
Reference | 26602496; 18413325; |
Functional description | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. |
Sequence | MRARPQVCEA LLFALALQTG VCYGIKWLAL SKTPSALALN QTQHCKQLEG LVSAQVQLCR 60 SNLELMHTVV HAAREVMKAC RRAFADMRWN CSSIELAPNY LLDLERGTRE SAFVYALSAA 120 AISHAIARAC TSGDLPGCSC GPVPGEPPGP GNRWGGCADN LSYGLLMGAK FSDAPMKVKK 180 TGSQANKLMR LHNSEVGRQA LRASLEMKCK CHGVSGSCSI RTCWKGLQEL QDVAADLKTR 240 YLSATKVVHR PMGTRKHLVP KDLDIRPVKD SELVYLQSSP DFCMKNEKVG SHGTQDRQCN 300 KTSNGSDSCD LMCCGRGYNP YTDRVVERCH CKYHWCCYVT CRRCERTVER YVCK 354 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.