| Tag | Content |
|---|---|
| Uniprot ID | P01135; A8K286; Q15577; Q53SK7; Q9BS56; Q9UEI3; Q9UKM1; Q9UKM2; Q9UKM3; |
| Entrez ID | 7039 |
| Genbank protein ID | AAF13491.1; BAF82840.1; AAY14705.1; AAF05089.1; AAP35479.1; AAA52530.1; AAF05090.1; AAF05091.1; CAA49806.1; EAW99810.1; AAY14793.1; AAD12238.1; AAP97822.2; AAH05308.1; EAW99812.1; AAA61157.1; AAA61159.1; |
| Genbank nucleotide ID | NM_001308158.1; NM_001308159.1; NM_003236.3; NM_001099691.2; |
| Ensembl protein ID | ENSP00000404099; ENSP00000387493; ENSP00000295400; |
| Ensembl nucleotide ID | ENSG00000163235 |
| Gene name | Protransforming growth factor alpha |
| Gene symbol | TGFA |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | CPO,CL/P |
| Developmental stage | |
| Data sources | Manually collected |
| Reference | 23940636; 1361101; 1673285; 14981713; 14755461; 1352354; 19444471; 10918043; 25191068; 9345615; 16953426; 26605011; 23029012; 24805869; 7825598; 2570526; 9684776; |
| Functional description | TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. |
| Sequence | MVPSAGQLAL FALGIVLAAC QALENSTSPL SADPPVAAAV VSHFNDCPDS HTQFCFHGTC 60 RFLVQEDKPA CVCHSGYVGA RCEHADLLAV VAASQKKQAI TALVVVSIVA LAVLIITCVL 120 IHCCQVRKHC EWCRALICRH EKPSALLKGR TACCHSETVV |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.