| Tag | Content |
|---|---|
| Uniprot ID | P01137; A8K792; Q9UCG4; |
| Entrez ID | 7040 |
| Genbank protein ID | CAA26580.1; AAP35909.1; CAA29283.1; AAH01180.1; AAH22242.1; BAF84596.1; AAA36735.1; EAW57032.1; AAH00125.1; |
| Genbank nucleotide ID | NM_000660.6 |
| Ensembl protein ID | |
| Ensembl nucleotide ID | |
| Gene name | Transforming growth factor beta-1 proprotein |
| Gene symbol | TGFB1 |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | |
| Developmental stage | |
| Data sources | Manually collected |
| Reference | 26954016 |
| Functional description | Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. |
| Sequence | MPPSGLRLLL LLLPLLWLLV LTPGRPAAGL STCKTIDMEL VKRKRIEAIR GQILSKLRLA 60 SPPSQGEVPP GPLPEAVLAL YNSTRDRVAG ESAEPEPEPE ADYYAKEVTR VLMVETHNEI 120 YDKFKQSTHS IYMFFNTSEL REAVPEPVLL SRAELRLLRL KLKVEQHVEL YQKYSNNSWR 180 YLSNRLLAPS DSPEWLSFDV TGVVRQWLSR GGEIEGFRLS AHCSCDSRDN TLQVDINGFT 240 TGRRGDLATI HGMNRPFLLL MATPLERAQH LQSSRHRRAL DTNYCFSSTE KNCCVRQLYI 300 DFRKDLGWKW IHEPKGYHAN FCLGPCPYIW SLDTQYSKVL ALYNQHNPGA SAAPCCVPQA 360 LEPLPIVYYV GRKPKVEQLS NMIVRSCKCS |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.