| Tag | Content |
|---|---|
| Uniprot ID | P04818; Q8WYK3; Q8WYK4; |
| Entrez ID | 7298 |
| Genbank protein ID | BAB83677.1; AAH83512.1; BAB83676.1; AAH02567.1; CAA26178.1; BAA00472.1; EAX01720.1; BAA00404.1; EAX01716.1; AAH13919.1; BAB93473.1; |
| Genbank nucleotide ID | NM_001071.2 |
| Ensembl protein ID | ENSP00000314727; ENSP00000315644; ENSP00000314902; |
| Ensembl nucleotide ID | ENSG00000176890 |
| Gene name | Thymidylate synthase |
| Gene symbol | TYMS |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | CPO,CL/P |
| Developmental stage | |
| Data sources | Manually collected |
| Reference | 23404871 |
| Functional description | Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. |
| Sequence | MPVAGSELPR RPLPPAAQER DAEPRPPHGE LQYLGQIQHI LRCGVRKDDR TGTGTLSVFG 60 MQARYSLRDE FPLLTTKRVF WKGVLEELLW FIKGSTNAKE LSSKGVKIWD ANGSRDFLDS 120 LGFSTREEGD LGPVYGFQWR HFGAEYRDME SDYSGQGVDQ LQRVIDTIKT NPDDRRIIMC 180 AWNPRDLPLM ALPPCHALCQ FYVVNSELSC QLYQRSGDMG LGVPFNIASY ALLTYMIAHI 240 TGLKPGDFIH TLGDAHIYLN HIEPLKIQLQ REPRPFPKLR ILRKVEKIDD FKAEDFQIEG 300 YNPHPTIKME MAV 313 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.