| Tag | Content |
|---|---|
| Uniprot ID | P09211; O00460; Q15690; Q5TZY3; |
| Entrez ID | 2950 |
| Genbank protein ID | AAC51237.1; AAV38753.1; AAA56823.1; AAV38752.1; CAA33508.1; CAG29357.1; AAP72967.1; CAA30894.1; CAA29794.1; CAA30847.1; AAA64919.1; AAC51280.1; AAC13869.1; AAH10915.1; |
| Genbank nucleotide ID | NM_000852.3 |
| Ensembl protein ID | ENSP00000381607 |
| Ensembl nucleotide ID | ENSG00000084207 |
| Gene name | Glutathione S-transferase P |
| Gene symbol | GSTP1 |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | CPO,CL/P |
| Developmental stage | |
| Data sources | Manually collected |
| Reference | 18159215 |
| Functional description | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276). Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. |
| Sequence | MPPYTVVYFP VRGRCAALRM LLADQGQSWK EEVVTVETWQ EGSLKASCLY GQLPKFQDGD 60 LTLYQSNTIL RHLGRTLGLY GKDQQEAALV DMVNDGVEDL RCKYISLIYT NYEAGKDDYV 120 KALPGQLKPF ETLLSQNQGG KTFIVGDQIS FADYNLLDLL LIHEVLAPGC LDAFPLLSAY 180 VGRLSARPKL KAFLASPEYV NLPINGNGKQ |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.