| Tag | Content |
|---|---|
| Uniprot ID | P09488; Q5GHG0; Q6FH88; Q8TC98; Q9UC96; |
| Entrez ID | 2944 |
| Genbank protein ID | CAA30821.1; AAT06768.1; AAA59203.1; CAG46666.1; CAA48636.1; AAH24005.1; CAA35817.1; AAR85979.1; AAT06767.1; |
| Genbank nucleotide ID | NM_146421.2; NM_000561.3; |
| Ensembl protein ID | ENSP00000311469; ENSP00000234981; |
| Ensembl nucleotide ID | ENSG00000134184 |
| Gene name | Glutathione S-transferase Mu 1 |
| Gene symbol | GSTM1 |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | |
| Developmental stage | |
| Data sources | Manually collected |
| Reference | 16135950 |
| Functional description | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276). |
| Sequence | MPMILGYWDI RGLAHAIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL 60 PYLIDGAHKI TQSNAILCYI ARKHNLCGET EEEKIRVDIL ENQTMDNHMQ LGMICYNPEF 120 EKLKPKYLEE LPEKLKLYSE FLGKRPWFAG NKITFVDFLV YDVLDLHRIF EPKCLDAFPN 180 LKDFISRFEG LEKISAYMKS SRFLPRPVFS KMAVWGNK 218 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.