CleftGeneDB-Search

Gene: GSTM1

Basic information

Tag	Content
Uniprot ID	P09488; Q5GHG0; Q6FH88; Q8TC98; Q9UC96;
Entrez ID	2944
Genbank protein ID	CAA30821.1; AAT06768.1; AAA59203.1; CAG46666.1; CAA48636.1; AAH24005.1; CAA35817.1; AAR85979.1; AAT06767.1;
Genbank nucleotide ID	NM_146421.2; NM_000561.3;
Ensembl protein ID	ENSP00000311469; ENSP00000234981;
Ensembl nucleotide ID	ENSG00000134184
Gene name	Glutathione S-transferase Mu 1
Gene symbol	GSTM1
Organism	Homo sapiens
NCBI taxa ID	9606
Cleft type
Developmental stage
Data sources	Manually collected
Reference	16135950
Functional description	Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) (PubMed:9084911). Participates in the formation of novel hepoxilin regioisomers (PubMed:21046276).
Sequence	MPMILGYWDI RGLAHAIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL 60 PYLIDGAHKI TQSNAILCYI ARKHNLCGET EEEKIRVDIL ENQTMDNHMQ LGMICYNPEF 120 EKLKPKYLEE LPEKLKLYSE FLGKRPWFAG NKITFVDFLV YDVLDLHRIF EPKCLDAFPN 180 LKDFISRFEG LEKISAYMKS SRFLPRPVFS KMAVWGNK 218

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Gene expression information

Gene expression in different tissues (GTEx V7)

Gene expression in different tissues (ENCODE)

Protein structural annotations

3D structure in PDB database

PDB ID
1GTU
1XW6
1XWK
1YJ6
2F3M
1XW6

Protein disorder information

Orthologous information

There is no orthologous record for this gene !

Other genetic variants/mutations

ID	Variant	Type	Disease	Chromosome\Coordinate	Evidence
COSM1332498	p.Met3Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000001.11:g.109687882G>T	NCI-TCGA Cosmic
rs756993138	p.Ile4Thr	missense variant	-	NC_000001.11:g.109687884T>C	ExAC,TOPMed,gnomAD
rs1173098385	p.Tyr7Cys	missense variant	-	NC_000001.11:g.109687893A>G	TOPMed,gnomAD
rs373606294	p.Tyr7Ter	stop gained	-	NC_000001.11:g.109687894C>G	ESP,ExAC,gnomAD
rs1192077068	p.Trp8Ter	stop gained	-	NC_000001.11:g.109687896G>A	gnomAD
rs184653774	p.Asp9Glu	missense variant	-	NC_000001.11:g.109687900C>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs200184852	p.Asp9Asn	missense variant	-	NC_000001.11:g.109687898G>A	1000Genomes
NCI-TCGA novel	p.Gly12Arg	missense variant	-	NC_000001.11:g.109687907G>A	NCI-TCGA
rs371083091	p.Gly12Val	missense variant	-	NC_000001.11:g.109687908G>T	ESP,ExAC,gnomAD
rs754442437	p.Ala14Ser	missense variant	-	NC_000001.11:g.109688173G>T	ExAC,gnomAD
rs754442437	p.Ala14Thr	missense variant	-	NC_000001.11:g.109688173G>A	ExAC,gnomAD
rs567320393	p.His15Gln	missense variant	-	NC_000001.11:g.109688178C>A	1000Genomes,ExAC,TOPMed,gnomAD
rs536289169	p.Ala16Val	missense variant	-	NC_000001.11:g.109688180C>T	1000Genomes,ExAC,TOPMed,gnomAD
rs1344469579	p.Ala16Thr	missense variant	-	NC_000001.11:g.109688179G>A	gnomAD
rs746171781	p.Ile17Val	missense variant	-	NC_000001.11:g.109688182A>G	ExAC,gnomAD
rs376564748	p.Arg18His	missense variant	-	NC_000001.11:g.109688186G>A	ESP,ExAC
rs553341658	p.Tyr23Cys	missense variant	-	NC_000001.11:g.109688201A>G	1000Genomes,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ser26Ter	stop gained	-	NC_000001.11:g.109688210C>G	NCI-TCGA
rs774437763	p.Ser26Ter	stop gained	-	NC_000001.11:g.109688210C>A	ExAC,TOPMed,gnomAD
rs774437763	p.Ser26Leu	missense variant	-	NC_000001.11:g.109688210C>T	ExAC,TOPMed,gnomAD
rs12068997	p.Ser27Arg	missense variant	-	NC_000001.11:g.109688214C>A	gnomAD
rs1212314215	p.Glu29Val	missense variant	-	NC_000001.11:g.109688219A>T	TOPMed,gnomAD
COSM3862139	p.Glu30Asp	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000001.11:g.109688223A>T	NCI-TCGA Cosmic
rs1259669984	p.Glu30Lys	missense variant	-	NC_000001.11:g.109688221G>A	gnomAD
rs1484761909	p.Lys31Glu	missense variant	-	NC_000001.11:g.109688224A>G	TOPMed,gnomAD
rs773434502	p.Met35Leu	missense variant	-	NC_000001.11:g.109688236A>C	ExAC,TOPMed,gnomAD
rs1156576312	p.Ala38Thr	missense variant	-	NC_000001.11:g.109688245G>A	gnomAD
rs1364241333	p.Tyr41Asn	missense variant	-	NC_000001.11:g.109688681T>A	gnomAD
rs748166413	p.Ser44Arg	missense variant	-	NC_000001.11:g.109688690A>C	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Trp46Ter	stop gained	-	NC_000001.11:g.109688698G>A	NCI-TCGA
rs772197093	p.Glu49Lys	missense variant	-	NC_000001.11:g.109688705G>A	ExAC,TOPMed,gnomAD
rs1402636704	p.Lys52Met	missense variant	-	NC_000001.11:g.109688715A>T	gnomAD
rs760927586	p.Asn59Ser	missense variant	-	NC_000001.11:g.109688736A>G	ExAC,TOPMed,gnomAD
rs1191778408	p.Ala67Thr	missense variant	-	NC_000001.11:g.109689069G>A	TOPMed,gnomAD
rs758844606	p.Gln72Pro	missense variant	-	NC_000001.11:g.109689085A>C	ExAC,gnomAD
rs778256041	p.Ser73Asn	missense variant	-	NC_000001.11:g.109689088G>A	ExAC,gnomAD
rs1381092855	p.Leu77Trp	missense variant	-	NC_000001.11:g.109689100T>G	gnomAD
rs201967146	p.Cys78Arg	missense variant	-	NC_000001.11:g.109689102T>C	1000Genomes
rs1289820434	p.Tyr79His	missense variant	-	NC_000001.11:g.109689105T>C	TOPMed,gnomAD
rs746113233	p.Arg82His	missense variant	-	NC_000001.11:g.109689115G>A	ExAC,gnomAD
rs781451004	p.Arg82Cys	missense variant	-	NC_000001.11:g.109689114C>T	ExAC,TOPMed,gnomAD
rs746113233	p.Arg82Leu	missense variant	-	NC_000001.11:g.109689115G>T	ExAC,gnomAD
rs1317720029	p.His84Pro	missense variant	-	NC_000001.11:g.109689121A>C	gnomAD
rs1161126530	p.His84Tyr	missense variant	-	NC_000001.11:g.109689120C>T	TOPMed
rs147668562	p.Asn85Ser	missense variant	-	NC_000001.11:g.109689124A>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs146668816	p.Asn85Lys	missense variant	-	NC_000001.11:g.109689125C>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1158626531	p.Gly88Arg	missense variant	-	NC_000001.11:g.109689227G>A	TOPMed,gnomAD
NCI-TCGA novel	p.Thr90Arg	missense variant	-	NC_000001.11:g.109689234C>G	NCI-TCGA
rs572826828	p.Glu92Asp	missense variant	-	NC_000001.11:g.109689241G>C	1000Genomes,ExAC,gnomAD
rs781192005	p.Arg96Cys	missense variant	-	NC_000001.11:g.109689251C>T	ExAC,gnomAD
rs199816990	p.Arg96Leu	missense variant	-	NC_000001.11:g.109689252G>T	1000Genomes,ExAC,TOPMed,gnomAD
rs199816990	p.Arg96His	missense variant	-	NC_000001.11:g.109689252G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs1354998497	p.Ile99Met	missense variant	-	NC_000001.11:g.109689262T>G	gnomAD
rs780458899	p.Asn102Lys	missense variant	-	NC_000001.11:g.109689271C>A	ExAC,TOPMed,gnomAD
rs1308880096	p.Thr104Ile	missense variant	-	NC_000001.11:g.109689276C>T	gnomAD
rs202002774	p.Met105Thr	missense variant	-	NC_000001.11:g.109689279T>C	1000Genomes,ExAC,TOPMed,gnomAD
rs768623239	p.Met105Val	missense variant	-	NC_000001.11:g.109689278A>G	ExAC,gnomAD
NCI-TCGA novel	p.Asp106Gly	missense variant	-	NC_000001.11:g.109689282A>G	NCI-TCGA
rs1187051979	p.His108Gln	missense variant	-	NC_000001.11:g.109689289T>G	TOPMed
rs1249584322	p.His108Arg	missense variant	-	NC_000001.11:g.109689288A>G	TOPMed
rs1449627796	p.His108Tyr	missense variant	-	NC_000001.11:g.109689287C>T	TOPMed
rs1266513721	p.Gly112Ser	missense variant	-	NC_000001.11:g.109689299G>A	TOPMed
rs1179816349	p.Gly112Val	missense variant	-	NC_000001.11:g.109689300G>T	TOPMed,gnomAD
rs748101558	p.Tyr116Cys	missense variant	-	NC_000001.11:g.109689312A>G	ExAC,gnomAD
rs1363667431	p.Asn117His	missense variant	-	NC_000001.11:g.109689314A>C	gnomAD
rs1349966213	p.Asn117Ser	missense variant	-	NC_000001.11:g.109689315A>G	TOPMed,gnomAD
NCI-TCGA novel	p.Pro118Ala	missense variant	-	NC_000001.11:g.109689317C>G	NCI-TCGA
NCI-TCGA novel	p.Phe120Tyr	missense variant	-	NC_000001.11:g.109689324T>A	NCI-TCGA
COSM893567	p.Leu123Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000001.11:g.109690278T>G	NCI-TCGA Cosmic
rs368395434	p.Lys126Thr	missense variant	-	NC_000001.11:g.109690287A>C	ESP,ExAC,gnomAD
rs1249221143	p.Tyr127Phe	missense variant	-	NC_000001.11:g.109690290A>T	gnomAD
rs1480110385	p.Leu128Ser	missense variant	-	NC_000001.11:g.109690293T>C	TOPMed,gnomAD
rs1198347422	p.Glu129Lys	missense variant	-	NC_000001.11:g.109690295G>A	gnomAD
rs1437688667	p.Glu130Lys	missense variant	-	NC_000001.11:g.109690298G>A	TOPMed
rs754817204	p.Glu140Lys	missense variant	-	NC_000001.11:g.109690328G>A	ExAC,gnomAD
rs778632616	p.Phe141Leu	missense variant	-	NC_000001.11:g.109690333T>A	ExAC,gnomAD
rs142484086	p.Arg145Trp	missense variant	-	NC_000001.11:g.109690343C>T	ESP,ExAC,TOPMed,gnomAD
rs1429155120	p.Arg145Gln	missense variant	-	NC_000001.11:g.109690344G>A	gnomAD
rs1172626028	p.Phe148Ser	missense variant	-	NC_000001.11:g.109690353T>C	gnomAD
rs140584594	p.Asn151Asp	missense variant	-	NC_000001.11:g.109690361A>G	1000Genomes,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ile153Val	missense variant	-	NC_000001.11:g.109690454A>G	NCI-TCGA
rs1452108643	p.Ile153Met	missense variant	-	NC_000001.11:g.109690456C>G	TOPMed
rs138440339	p.Leu159Val	missense variant	-	NC_000001.11:g.109690472C>G	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs766633589	p.Val160Ile	missense variant	-	NC_000001.11:g.109690475G>A	ExAC,gnomAD
rs146527074	p.Val160Ala	missense variant	-	NC_000001.11:g.109690476T>C	ExAC,gnomAD
NCI-TCGA novel	p.Asp162Tyr	missense variant	-	NC_000001.11:g.109690481G>T	NCI-TCGA
rs544766466	p.Asp162Val	missense variant	-	NC_000001.11:g.109690482A>T	ExAC,TOPMed,gnomAD
rs1490055622	p.Val163Phe	missense variant	-	NC_000001.11:g.109690484G>T	TOPMed
rs149344762	p.Leu166Ile	missense variant	-	NC_000001.11:g.109690493C>A	ESP,ExAC,gnomAD
rs146001438	p.His167Tyr	missense variant	-	NC_000001.11:g.109690496C>T	ESP,ExAC,TOPMed,gnomAD
rs146001438	p.His167Asn	missense variant	-	NC_000001.11:g.109690496C>A	ESP,ExAC,TOPMed,gnomAD
rs143315534	p.His167Gln	missense variant	-	NC_000001.11:g.109690498C>G	1000Genomes,ESP,ExAC,gnomAD
rs780734466	p.Arg168His	missense variant	-	NC_000001.11:g.109690500G>A	ExAC,TOPMed,gnomAD
rs375154572	p.Arg168Cys	missense variant	-	NC_000001.11:g.109690499C>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs745391866	p.Glu171Gly	missense variant	-	NC_000001.11:g.109690509A>G	ExAC,gnomAD
rs1240418285	p.Pro172His	missense variant	-	NC_000001.11:g.109690512C>A	gnomAD
rs1218647492	p.Pro172Ser	missense variant	-	NC_000001.11:g.109690511C>T	gnomAD
rs1487970761	p.Lys173Glu	missense variant	-	NC_000001.11:g.109690514A>G	gnomAD
rs769295127	p.Lys173Arg	missense variant	-	NC_000001.11:g.109690515A>G	ExAC,TOPMed,gnomAD
rs1065411	p.Lys173Asn	missense variant	-	NC_000001.11:g.109690516G>T	UniProt,dbSNP
VAR_003617	p.Lys173Asn	missense variant	-	NC_000001.11:g.109690516G>T	UniProt
rs1065411	p.Lys173Asn	missense variant	-	NC_000001.11:g.109690516G>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1065411	p.Lys173Asn	missense variant	-	NC_000001.11:g.109690516G>C	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1474361051	p.Leu175Ser	missense variant	-	NC_000001.11:g.109690521T>C	gnomAD
rs762064926	p.Asp176Asn	missense variant	-	NC_000001.11:g.109690523G>A	ExAC,gnomAD
rs1156902745	p.Ala177Pro	missense variant	-	NC_000001.11:g.109690526G>C	gnomAD
rs1156902745	p.Ala177Ser	missense variant	-	NC_000001.11:g.109690526G>T	gnomAD
rs773852055	p.Pro179Ser	missense variant	-	NC_000001.11:g.109690532C>T	ExAC,gnomAD
rs72549312	p.Pro179Leu	missense variant	-	NC_000001.11:g.109690533C>T	gnomAD
rs369344514	p.Asn180Asp	missense variant	-	NC_000001.11:g.109690535A>G	ESP,ExAC,TOPMed,gnomAD
COSM3984066	p.Phe184Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000001.11:g.109690547T>G	NCI-TCGA Cosmic
rs1446890310	p.Ile185Asn	missense variant	-	NC_000001.11:g.109690551T>A	gnomAD
rs1374582670	p.Ser186Phe	missense variant	-	NC_000001.11:g.109690554C>T	gnomAD
rs72549313	p.Arg187Cys	missense variant	-	NC_000001.11:g.109690556C>T	1000Genomes,ExAC,TOPMed,gnomAD
rs753904217	p.Arg187His	missense variant	-	NC_000001.11:g.109690557G>A	ExAC,TOPMed,gnomAD
rs1353658341	p.Glu189Lys	missense variant	-	NC_000001.11:g.109690562G>A	gnomAD
rs1305712180	p.Met198Val	missense variant	-	NC_000001.11:g.109693230A>G	gnomAD
rs1343028679	p.Ser201Arg	missense variant	-	NC_000001.11:g.109693241C>A	gnomAD
rs371247780	p.Arg202His	missense variant	-	NC_000001.11:g.109693243G>A	ESP,gnomAD
NCI-TCGA novel	p.Leu204Ile	missense variant	-	NC_000001.11:g.109693248C>A	NCI-TCGA
rs1273891660	p.Leu204Pro	missense variant	-	NC_000001.11:g.109693249T>C	gnomAD
rs1481745571	p.Arg206Ser	missense variant	-	NC_000001.11:g.109693256A>T	TOPMed
rs449856	p.Ser210Thr	missense variant	-	NC_000001.11:g.109693266T>A	1000Genomes,TOPMed,gnomAD
rs533860247	p.Ala213Thr	missense variant	-	NC_000001.11:g.109693275G>A	1000Genomes,ExAC,TOPMed,gnomAD
rs771524140	p.Val214Gly	missense variant	-	NC_000001.11:g.109693279T>G	ExAC,gnomAD
rs777299993	p.Trp215Cys	missense variant	-	NC_000001.11:g.109693283G>C	ExAC,TOPMed,gnomAD
rs1393211629	p.Gly216Val	missense variant	-	NC_000001.11:g.109693285G>T	TOPMed,gnomAD
rs759510582	p.Ter219Trp	stop lost	-	NC_000001.11:g.109693294A>G	ExAC,gnomAD

Disease or phenotype associated information

Disease ID	Disease Name	Disease Type	Source
C0000735	Abdominal Neoplasms	group	BEFREE
C0000768	Congenital Abnormality	group	BEFREE
C0001339	Acute pancreatitis	disease	BEFREE
C0001418	Adenocarcinoma	group	BEFREE;LHGDN
C0001430	Adenoma	group	BEFREE
C0001857	AIDS related complex	disease	BEFREE
C0001973	Alcoholic Intoxication, Chronic	disease	BEFREE;PSYGENET
C0002395	Alzheimer's Disease	disease	BEFREE
C0002874	Aplastic Anemia	disease	BEFREE;LHGDN
C0002875	Cooley's anemia	disease	BEFREE
C0002895	Anemia, Sickle Cell	disease	BEFREE
C0003467	Anxiety	disease	BEFREE
C0003469	Anxiety Disorders	group	BEFREE
C0003850	Arteriosclerosis	disease	BEFREE
C0003873	Rheumatoid Arthritis	disease	BEFREE;LHGDN
C0004096	Asthma	disease	BEFREE;CTD_human;LHGDN
C0004114	Astrocytoma	disease	BEFREE;LHGDN
C0004153	Atherosclerosis	disease	BEFREE;CTD_human
C0004352	Autistic Disorder	group	BEFREE;CTD_human;LHGDN
C0004364	Autoimmune Diseases	group	BEFREE
C0004403	Autosome Abnormalities	group	CTD_human
C0004509	Azoospermia	disease	BEFREE
C0004779	Basal Cell Nevus Syndrome	disease	BEFREE
C0004943	Behcet Syndrome	disease	LHGDN
C0005586	Bipolar Disorder	disease	BEFREE;PSYGENET
C0005684	Malignant neoplasm of urinary bladder	disease	BEFREE;CTD_human
C0005695	Bladder Neoplasm	group	BEFREE;CTD_human;LHGDN
C0006111	Brain Diseases	group	BEFREE
C0006118	Brain Neoplasms	group	BEFREE;LHGDN
C0006142	Malignant neoplasm of breast	disease	BEFREE
C0007102	Malignant tumor of colon	disease	BEFREE
C0007103	Malignant neoplasm of endometrium	disease	BEFREE
C0007107	Malignant neoplasm of larynx	disease	BEFREE
C0007113	Rectal Carcinoma	disease	BEFREE
C0007114	Malignant neoplasm of skin	disease	BEFREE
C0007115	Malignant neoplasm of thyroid	disease	BEFREE
C0007121	Bronchogenic Carcinoma	disease	BEFREE
C0007131	Non-Small Cell Lung Carcinoma	disease	BEFREE
C0007134	Renal Cell Carcinoma	disease	BEFREE;CTD_human
C0007137	Squamous cell carcinoma	disease	BEFREE;CTD_human;LHGDN
C0007138	Carcinoma, Transitional Cell	disease	BEFREE
C0007222	Cardiovascular Diseases	group	BEFREE
C0007847	Malignant tumor of cervix	disease	BEFREE
C0007868	Cervical dysplasia	disease	BEFREE
C0007873	Uterine Cervical Neoplasm	disease	BEFREE
C0008312	Primary biliary cirrhosis	disease	BEFREE
C0008370	Cholestasis	disease	BEFREE
C0008625	Chromosome Aberrations	group	CTD_human
C0008626	Congenital chromosomal disease	group	BEFREE
C0008677	Bronchitis, Chronic	disease	BEFREE
C0008924	Cleft upper lip	disease	BEFREE
C0008925	Cleft Palate	disease	BEFREE
C0009324	Ulcerative Colitis	disease	BEFREE
C0009375	Colonic Neoplasms	group	BEFREE;LHGDN
C0009402	Colorectal Carcinoma	disease	BEFREE;CTD_human
C0009404	Colorectal Neoplasms	group	BEFREE;CTD_human;LHGDN
C0010054	Coronary Arteriosclerosis	disease	BEFREE
C0010068	Coronary heart disease	disease	BEFREE
C0010346	Crohn Disease	disease	BEFREE
C0010674	Cystic Fibrosis	disease	BEFREE
C0011570	Mental Depression	disease	BEFREE;PSYGENET
C0011581	Depressive disorder	disease	BEFREE;PSYGENET
C0011609	Drug Eruptions	group	LHGDN
C0011615	Dermatitis, Atopic	disease	BEFREE;LHGDN
C0011847	Diabetes	disease	BEFREE
C0011849	Diabetes Mellitus	group	BEFREE;LHGDN
C0011854	Diabetes Mellitus, Insulin-Dependent	disease	BEFREE
C0011860	Diabetes Mellitus, Non-Insulin-Dependent	disease	BEFREE;CTD_human
C0011881	Diabetic Nephropathy	disease	BEFREE
C0011882	Diabetic Neuropathies	group	BEFREE
C0011884	Diabetic Retinopathy	disease	BEFREE
C0013146	Drug abuse	disease	BEFREE
C0013182	Drug Allergy	phenotype	CTD_human
C0013404	Dyspnea	phenotype	BEFREE
C0013595	Eczema	disease	BEFREE
C0014175	Endometriosis	disease	BEFREE;LHGDN
C0014859	Esophageal Neoplasms	group	BEFREE;LHGDN
C0015397	Disorder of eye	group	BEFREE
C0015625	Fanconi Anemia	disease	BEFREE
C0016034	Breast Fibrocystic Disease	disease	BEFREE
C0016059	Fibrosis	phenotype	LHGDN
C0016978	gallbladder neoplasm	disease	LHGDN
C0017154	Gastritis, Atrophic	disease	BEFREE
C0017601	Glaucoma	disease	BEFREE
C0017612	Glaucoma, Open-Angle	disease	LHGDN
C0017636	Glioblastoma	disease	BEFREE
C0017638	Glioma	disease	BEFREE
C0018133	Graft-vs-Host Disease	disease	BEFREE
C0018213	Graves Disease	disease	BEFREE
C0018621	Hay fever	disease	BEFREE
C0018671	Head and Neck Neoplasms	group	LHGDN
C0018790	Cardiac Arrest	disease	BEFREE
C0019045	Hemoglobinopathies	group	BEFREE
C0019158	Hepatitis	disease	BEFREE;LHGDN
C0019159	Hepatitis A	disease	BEFREE
C0019163	Hepatitis B	disease	BEFREE
C0019193	Hepatitis, Toxic	disease	CTD_human
C0019196	Hepatitis C	disease	BEFREE
C0019829	Hodgkin Disease	disease	BEFREE
C0020538	Hypertensive disease	group	BEFREE;LHGDN;RGD
C0020557	Hypertriglyceridemia	phenotype	BEFREE
C0021294	Infant, Premature	phenotype	BEFREE
C0021359	Infertility	phenotype	LHGDN
C0021364	Male infertility	disease	BEFREE
C0021390	Inflammatory Bowel Diseases	group	BEFREE;LHGDN
C0022353	Neonatal Jaundice	phenotype	LHGDN
C0022593	Keratosis	disease	BEFREE;LHGDN
C0022602	Actinic keratosis	disease	BEFREE
C0022658	Kidney Diseases	group	BEFREE
C0022661	Kidney Failure, Chronic	disease	LHGDN
C0023055	Laryngeal neoplasm	disease	LHGDN
C0023267	Fibroid Tumor	group	BEFREE
C0023343	Leprosy	disease	BEFREE
C0023418	leukemia	disease	BEFREE;CTD_human;LHGDN
C0023434	Chronic Lymphocytic Leukemia	disease	BEFREE;LHGDN
C0023449	Acute lymphocytic leukemia	disease	BEFREE
C0023452	Childhood Acute Lymphoblastic Leukemia	disease	BEFREE
C0023467	Leukemia, Myelocytic, Acute	disease	BEFREE;LHGDN
C0023473	Myeloid Leukemia, Chronic	disease	BEFREE
C0023487	Acute Promyelocytic Leukemia	disease	BEFREE
C0023493	Adult T-Cell Lymphoma/Leukemia	disease	BEFREE
C0023530	Leukopenia	disease	BEFREE
C0023531	Leukoplakia	disease	BEFREE
C0023532	Leukoplakia, Oral	disease	BEFREE;LHGDN
C0023890	Liver Cirrhosis	disease	BEFREE;RGD
C0023891	Liver Cirrhosis, Alcoholic	disease	BEFREE
C0023893	Liver Cirrhosis, Experimental	disease	CTD_human
C0023895	Liver diseases	group	BEFREE
C0023896	Alcoholic Liver Diseases	group	BEFREE
C0023903	Liver neoplasms	group	CTD_human
C0024115	Lung diseases	group	BEFREE
C0024117	Chronic Obstructive Airway Disease	disease	BEFREE
C0024121	Lung Neoplasms	group	BEFREE;CTD_human;LHGDN
C0024141	Lupus Erythematosus, Systemic	disease	BEFREE
C0024299	Lymphoma	group	BEFREE;LHGDN
C0024301	Lymphoma, Follicular	disease	BEFREE
C0024305	Lymphoma, Non-Hodgkin	disease	BEFREE;LHGDN
C0024530	Malaria	disease	BEFREE
C0024623	Malignant neoplasm of stomach	disease	BEFREE
C0025149	Medulloblastoma	disease	BEFREE
C0025202	melanoma	disease	BEFREE
C0025286	Meningioma	disease	BEFREE
C0025500	Mesothelioma	disease	CTD_human;LHGDN
C0025568	Metaplasia	phenotype	LHGDN
C0026640	Mouth Neoplasms	group	LHGDN
C0026764	Multiple Myeloma	disease	BEFREE
C0026769	Multiple Sclerosis	disease	BEFREE;LHGDN
C0027051	Myocardial Infarction	disease	BEFREE;LHGDN
C0027497	Nausea	phenotype	BEFREE
C0027627	Neoplasm Metastasis	phenotype	BEFREE;LHGDN
C0027663	Neoplasms, Multiple Primary	group	BEFREE
C0027726	Nephrotic Syndrome	group	LHGDN
C0027819	Neuroblastoma	group	BEFREE
C0027947	Neutropenia	disease	BEFREE
C0028754	Obesity	disease	BEFREE
C0028945	oligodendroglioma	disease	LHGDN
C0028960	Oligospermia	disease	BEFREE
C0029132	Disorder of the optic nerve	group	BEFREE
C0029134	Optic Neuritis	disease	BEFREE
C0029463	Osteosarcoma	disease	BEFREE
C0029925	Ovarian Carcinoma	disease	BEFREE
C0030305	Pancreatitis	disease	LHGDN
C0030312	Pancytopenia	disease	BEFREE
C0030354	Papilloma	disease	BEFREE
C0030567	Parkinson Disease	disease	BEFREE;CTD_human;LHGDN
C0031099	Periodontitis	disease	BEFREE;LHGDN
C0031347	Pharyngeal Neoplasms	group	LHGDN
C0031736	Polymorphous light eruption	disease	BEFREE
C0032000	Pituitary Adenoma	disease	BEFREE
C0032019	Pituitary Neoplasms	group	BEFREE
C0032285	Pneumonia	disease	BEFREE
C0032460	Polycystic Ovary Syndrome	disease	BEFREE
C0032463	Polycythemia Vera	disease	BEFREE
C0032580	Adenomatous Polyposis Coli	disease	BEFREE
C0032927	Precancerous Conditions	group	BEFREE
C0033375	Prolactinoma	disease	BEFREE
C0033578	Prostatic Neoplasms	group	CTD_human;LHGDN
C0033860	Psoriasis	disease	BEFREE
C0034341	Pyruvate Carboxylase Deficiency Disease	disease	BEFREE
C0034734	Raynaud Disease	disease	CTD_human
C0034735	Raynaud Phenomenon	disease	CTD_human
C0034885	Rectal Neoplasms	group	BEFREE
C0036323	Schistosomiasis	disease	BEFREE
C0036341	Schizophrenia	disease	BEFREE;PSYGENET
C0036351	Residual schizophrenia	disease	BEFREE
C0036421	Systemic Scleroderma	disease	BEFREE
C0036646	Age-related cataract	disease	BEFREE
C0037019	Shy-Drager Syndrome	disease	BEFREE
C0037090	Signs and Symptoms, Respiratory	group	BEFREE
C0037274	Dermatologic disorders	group	CTD_human
C0037285	Skin Manifestations	group	BEFREE
C0037286	Skin Neoplasms	group	BEFREE
C0038356	Stomach Neoplasms	group	BEFREE;LHGDN
C0038454	Cerebrovascular accident	group	BEFREE
C0038868	Progressive supranuclear palsy	disease	BEFREE
C0039590	Testicular Neoplasms	group	LHGDN
C0040136	Thyroid Neoplasm	disease	LHGDN
C0041107	Trisomy	group	BEFREE
C0041296	Tuberculosis	disease	BEFREE
C0041582	Ulcer	disease	BEFREE
C0042109	Urticaria	disease	CTD_human
C0042133	Uterine Fibroids	group	BEFREE
C0042341	Varicocele	disease	BEFREE
C0042769	Virus Diseases	group	BEFREE
C0042900	Vitiligo	disease	BEFREE
C0042963	Vomiting	phenotype	BEFREE
C0043144	Wheezing	phenotype	BEFREE
C0043346	Xeroderma Pigmentosum	disease	BEFREE
C0079731	B-Cell Lymphomas	group	BEFREE
C0079744	Diffuse Large B-Cell Lymphoma	disease	BEFREE
C0079745	Lymphoma, Large-Cell, Follicular	disease	BEFREE
C0085183	Neoplasms, Second Primary	group	CTD_human
C0085580	Essential Hypertension	disease	BEFREE
C0085584	Encephalopathies	group	BEFREE
C0085669	Acute leukemia	disease	BEFREE
C0085695	Chronic gastritis	disease	BEFREE
C0086543	Cataract	disease	BEFREE;LHGDN
C0086696	Neoplasms, Therapy-Associated	group	CTD_human
C0149782	Squamous cell carcinoma of lung	disease	BEFREE
C0149925	Small cell carcinoma of lung	disease	BEFREE
C0149931	Migraine Disorders	group	BEFREE
C0151546	Oral Cavity Carcinoma	disease	BEFREE
C0151744	Myocardial Ischemia	disease	BEFREE
C0151779	Cutaneous Melanoma	disease	BEFREE
C0152013	Adenocarcinoma of lung (disorder)	disease	BEFREE
C0152018	Esophageal carcinoma	disease	BEFREE
C0152451	Chronic glomerulonephritis	disease	BEFREE
C0153381	Malignant neoplasm of mouth	disease	BEFREE
C0153382	Malignant neoplasm of oropharynx	disease	BEFREE
C0153392	Malignant neoplasm of nasopharynx	disease	BEFREE
C0153405	Malignant neoplasm of pharynx	disease	BEFREE
C0153446	Malignant neoplasm of anus	disease	BEFREE
C0153452	Malignant neoplasm of gallbladder	disease	BEFREE
C0155626	Acute myocardial infarction	disease	BEFREE
C0155877	Allergic asthma	disease	BEFREE
C0162309	Adrenoleukodystrophy	disease	BEFREE
C0162566	Porphyria Cutanea Tarda	disease	BEFREE
C0205748	Dysplastic Nevus	disease	BEFREE
C0206704	Carcinoma, Large Cell	disease	BEFREE
C0206708	Cervical Intraepithelial Neoplasia	disease	BEFREE
C0206720	Squamous Cell Neoplasms	group	LHGDN
C0220603	Childhood Brain Neoplasm	disease	BEFREE
C0220612	Childhood Non-Hodgkin Lymphoma	disease	BEFREE
C0220615	Adult Acute Myeloblastic Leukemia	disease	BEFREE
C0220621	Childhood Acute Myeloid Leukemia	disease	BEFREE
C0220624	Adult Brain Neoplasm	disease	BEFREE
C0220641	Lip and Oral Cavity Carcinoma	disease	BEFREE
C0233794	Memory impairment	phenotype	BEFREE
C0235782	Gallbladder Carcinoma	disease	BEFREE
C0235974	Pancreatic carcinoma	disease	BEFREE
C0236663	Alcohol withdrawal syndrome	disease	BEFREE;PSYGENET
C0236733	Amphetamine-Related Disorders	group	CTD_human
C0236804	Amphetamine Addiction	disease	CTD_human
C0236807	Amphetamine Abuse	disease	CTD_human
C0236970	Alcohol-Induced Disorders	group	BEFREE
C0238301	Cancer of Nasopharynx	disease	BEFREE
C0241910	Hepatitis, Autoimmune	disease	BEFREE
C0242379	Malignant neoplasm of lung	disease	BEFREE;CTD_human
C0242383	Age related macular degeneration	disease	BEFREE;LHGDN
C0242647	Mucosa-Associated Lymphoid Tissue Lymphoma	disease	BEFREE
C0260037	Multiple tumors	phenotype	BEFREE
C0262584	Carcinoma, Small Cell	disease	BEFREE;LHGDN
C0263454	Chloracne	disease	BEFREE;CTD_human
C0264219	Acute respiratory disease	group	BEFREE
C0264408	Childhood asthma	disease	BEFREE
C0268138	Xeroderma Pigmentosum, Complementation Group D	disease	BEFREE
C0268398	Familial lichen amyloidosis	disease	BEFREE
C0270715	Degenerative Diseases, Central Nervous System	group	CTD_human
C0271160	Cortical cataract	phenotype	BEFREE
C0271650	Impaired glucose tolerance	phenotype	BEFREE
C0271907	Acquired aplastic anemia	disease	BEFREE
C0271979	Thalassemia Intermedia	disease	BEFREE
C0278583	Cervical carcinoma stage IIB	disease	BEFREE
C0278701	Gastric Adenocarcinoma	disease	BEFREE
C0278996	Malignant Head and Neck Neoplasm	disease	BEFREE
C0279626	Squamous cell carcinoma of esophagus	disease	BEFREE
C0279637	Anal carcinoma	disease	BEFREE
C0279671	Cervical Squamous Cell Carcinoma	disease	BEFREE
C0279680	Transitional cell carcinoma of bladder	disease	BEFREE
C0279681	Bladder Squamous Cell Carcinoma	disease	BEFREE
C0279702	Conventional (Clear Cell) Renal Cell Carcinoma	disease	BEFREE;CTD_human
C0280220	stage, ovarian epithelial cancer	disease	BEFREE
C0280324	Laryngeal Squamous Cell Carcinoma	disease	BEFREE
C0280449	secondary acute myeloid leukemia	disease	BEFREE
C0281361	Adenocarcinoma of pancreas	disease	BEFREE
C0282193	Iron Overload	disease	LHGDN
C0302592	Cervix carcinoma	disease	BEFREE
C0333704	Chromosome Breaks	phenotype	CTD_human
C0333875	High-Grade Squamous Intraepithelial Lesions	phenotype	BEFREE
C0338507	Non-arteritic ischemic optic neuropathy	disease	BEFREE
C0338508	Optic Atrophy, Autosomal Dominant	disease	BEFREE
C0339573	Glaucoma, Primary Open Angle	disease	BEFREE
C0341439	Chronic liver disease	group	BEFREE
C0341858	Endometriosis of uterus	disease	BEFREE
C0345904	Malignant neoplasm of liver	disease	CTD_human
C0345967	Malignant mesothelioma	disease	BEFREE;CTD_human
C0346647	Malignant neoplasm of pancreas	disease	BEFREE
C0348801	Group B streptococcal pneumonia	disease	BEFREE
C0375071	Malignant neoplasm of vulva	disease	BEFREE
C0376358	Malignant neoplasm of prostate	disease	BEFREE;CTD_human
C0376628	Chromosome Breakage	phenotype	CTD_human
C0376670	Pancreatitis, Alcoholic	disease	BEFREE
C0400966	Non-alcoholic Fatty Liver Disease	disease	BEFREE;CTD_human
C0433992	Noise-induced temporary threshold shift	disease	BEFREE
C0442874	Neuropathy	group	BEFREE
C0476089	Endometrial Carcinoma	disease	BEFREE
C0521707	Bilateral cataracts (disorder)	disease	BEFREE
C0524620	Metabolic Syndrome X	disease	BEFREE
C0524851	Neurodegenerative Disorders	group	BEFREE;CTD_human
C0524909	Hepatitis B, Chronic	disease	BEFREE
C0542271	Environmental Carcinogenesis	phenotype	BEFREE
C0546837	Malignant neoplasm of esophagus	disease	BEFREE
C0549473	Thyroid carcinoma	disease	BEFREE
C0577631	Carotid Atherosclerosis	disease	BEFREE
C0585186	Cutaneous hypersensitivity	disease	BEFREE
C0585442	Osteosarcoma of bone	disease	BEFREE
C0595989	Carcinoma of larynx	disease	BEFREE
C0596263	Carcinogenesis	phenotype	BEFREE
C0598766	Leukemogenesis	disease	BEFREE
C0600139	Prostate carcinoma	disease	BEFREE
C0677055	CARCINOMA OF VULVA	disease	BEFREE
C0677886	Epithelial ovarian cancer	disease	BEFREE
C0677898	invasive cancer	phenotype	BEFREE
C0678222	Breast Carcinoma	disease	BEFREE
C0684249	Carcinoma of lung	disease	BEFREE
C0685938	Malignant neoplasm of gastrointestinal tract	disease	BEFREE
C0686619	Secondary malignant neoplasm of lymph node	disease	BEFREE
C0687132	heavy drinking	disease	BEFREE
C0699790	Colon Carcinoma	disease	BEFREE
C0699791	Stomach Carcinoma	disease	BEFREE
C0699885	Carcinoma of bladder	disease	BEFREE
C0699893	Skin carcinoma	disease	BEFREE
C0700095	Central neuroblastoma	disease	BEFREE
C0730328	Central Serous Chorioretinopathy	disease	BEFREE
C0730607	Severe chronic obstructive pulmonary disease	disease	BEFREE
C0740457	Malignant neoplasm of kidney	disease	BEFREE
C0741682	Premenopausal breast cancer	disease	BEFREE
C0742343	Acute Chest Syndrome	disease	BEFREE
C0746102	Chronic lung disease	group	BEFREE
C0747845	early pregnancy	phenotype	BEFREE
C0751688	Malignant Squamous Cell Neoplasm	disease	BEFREE
C0751733	Degenerative Diseases, Spinal Cord	disease	CTD_human
C0810031	alcohol-related liver disease	disease	BEFREE
C0810364	Cleft Lip with or without Cleft Palate	disease	BEFREE
C0812413	Malignant Pleural Mesothelioma	disease	BEFREE
C0815107	psychological distress	disease	BEFREE
C0848558	Hypospadias	group	BEFREE
C0850666	Infection caused by Helicobacter pylori	disease	BEFREE
C0850741	Smoker's lung	disease	BEFREE
C0860207	Drug-Induced Liver Disease	disease	BEFREE;CTD_human
C0877578	Treatment related secondary malignancy	phenotype	CTD_human
C0919267	ovarian neoplasm	disease	BEFREE;LHGDN
C0940937	precancerous lesions	phenotype	BEFREE
C0948380	Colorectal cancer metastatic	disease	BEFREE
C0948441	Venoocclusive disease	group	BEFREE
C0949059	Polyp of large intestine	disease	BEFREE
C1140680	Malignant neoplasm of ovary	disease	BEFREE
C1168401	Squamous cell carcinoma of the head and neck	disease	BEFREE
C1258085	Barrett Epithelium	disease	BEFREE
C1262760	Hepatitis, Drug-Induced	disease	CTD_human
C1266042	Chromophobe Renal Cell Carcinoma	disease	CTD_human
C1266043	Sarcomatoid Renal Cell Carcinoma	disease	CTD_human
C1266044	Collecting Duct Carcinoma of the Kidney	disease	CTD_human
C1291317	Deficiency of transferase	group	BEFREE
C1292769	Precursor B-cell lymphoblastic leukemia	disease	BEFREE
C1292778	Chronic myeloproliferative disorder	disease	BEFREE
C1302401	Adenoma of large intestine	disease	BEFREE
C1304119	Chronic stable plaque psoriasis	disease	BEFREE
C1306460	Primary malignant neoplasm of lung	disease	BEFREE
C1306837	Papillary Renal Cell Carcinoma	disease	CTD_human
C1319315	Adenocarcinoma of large intestine	disease	BEFREE
C1332153	Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome	disease	BEFREE
C1332922	Cervical Squamous Intraepithelial Neoplasia	disease	BEFREE
C1332977	Childhood Leukemia	disease	BEFREE
C1333468	Esophageal Squamous Intraepithelial Neoplasia	disease	BEFREE
C1333763	Gastric Cardia Carcinoma	disease	BEFREE
C1333990	Hereditary Nonpolyposis Colorectal Cancer	disease	BEFREE
C1336076	Sporadic Breast Carcinoma	disease	BEFREE
C1336708	Testicular Germ Cell Tumor	disease	BEFREE
C1336735	Treatment related acute myeloid leukaemia	disease	BEFREE
C1378703	Renal carcinoma	disease	BEFREE
C1402315	Vascular lesions	disease	BEFREE
C1458155	Mammary Neoplasms	group	LHGDN
C1512409	Hepatocarcinogenesis	disease	BEFREE
C1527249	Colorectal Cancer	disease	BEFREE;CTD_human
C1527336	Sjogren's Syndrome	disease	BEFREE
C1559154	Rash and Dermatitis Adverse Event Associated with Chemoradiation	disease	BEFREE
C1561643	Chronic Kidney Diseases	group	BEFREE
C1563937	Atherogenesis	phenotype	CTD_human
C1621958	Glioblastoma Multiforme	disease	BEFREE
C1623038	Cirrhosis	disease	BEFREE
C1691215	Penile hypospadias	disease	BEFREE
C1704272	Benign Prostatic Hyperplasia	disease	BEFREE
C1762616	Meningioma, benign, no ICD-O subtype	disease	BEFREE
C1827377	Slow acetylator due to N-acetyltransferase enzyme variant	disease	BEFREE
C1827820	Fast acetylator due to N-acetyltransferase enzyme variant	disease	BEFREE
C1837218	Cleft palate, isolated	disease	BEFREE
C1847835	VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)	disease	BEFREE
C1861305	TARSAL-CARPAL COALITION SYNDROME	disease	BEFREE
C1883486	Uterine Corpus Cancer	disease	BEFREE
C1956346	Coronary Artery Disease	disease	BEFREE;LHGDN
C1961102	Precursor Cell Lymphoblastic Leukemia Lymphoma	disease	BEFREE
C2145472	Urothelial Carcinoma	disease	BEFREE
C2239176	Liver carcinoma	disease	BEFREE;CTD_human;LHGDN
C2349952	Oropharyngeal Carcinoma	disease	BEFREE
C2750737	DIARRHEA 5, WITH TUFTING ENTEROPATHY, CONGENITAL	disease	BEFREE
C2931822	Nasopharyngeal carcinoma	disease	BEFREE
C2981150	Uranostaphyloschisis	disease	BEFREE
C3150911	GASTRIC CANCER, INTESTINAL	disease	BEFREE
C3160718	PARKINSON DISEASE, LATE-ONSET	disease	BEFREE
C3241937	Nonalcoholic Steatohepatitis	disease	BEFREE;CTD_human
C3266628	Persistent asthma	disease	BEFREE
C3463824	MYELODYSPLASTIC SYNDROME	group	BEFREE;LHGDN
C3658290	Drug-Induced Acute Liver Injury	disease	CTD_human
C3665444	Neutrophilia (disorder)	disease	BEFREE
C3714636	Pneumonitis	disease	BEFREE
C3811653	Experimental Organism Basal Cell Carcinoma	phenotype	BEFREE
C3825816	Pneumonia in children	disease	BEFREE
C4048328	cervical cancer	disease	BEFREE
C4086165	Childhood Neuroblastoma	disease	BEFREE
C4225412	Spondylo-ocular syndrome	disease	BEFREE
C4277682	Chemical and Drug Induced Liver Injury	disease	CTD_human
C4279912	Chemically-Induced Liver Toxicity	disease	CTD_human

Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO ID	GO Term	Evidence
GO:0004364	glutathione transferase activity	IBA
GO:0004364	glutathione transferase activity	IDA
GO:0019899	enzyme binding	IPI
GO:0042803	protein homodimerization activity	IPI
GO:0043295	glutathione binding	IDA

GO:Biological Process

GO ID	GO Term	Evidence
GO:0006749	glutathione metabolic process	IBA
GO:0006749	glutathione metabolic process	IDA
GO:0018916	nitrobenzene metabolic process	IDA
GO:0042178	xenobiotic catabolic process	IDA
GO:0070458	cellular detoxification of nitrogen compound	IDA
GO:1901687	glutathione derivative biosynthetic process	TAS

GO:Cellular Component

GO ID	GO Term	Evidence
GO:0005737	cytoplasm	IDA
GO:0005829	cytosol	IDA
GO:0005829	cytosol	TAS
GO:0045171	intercellular bridge	IDA

Reactome Pathway

Reactome ID	Reactome Term	Evidence
R-HSA-1430728	Metabolism	TAS
R-HSA-156580	Phase II - Conjugation of compounds	TAS
R-HSA-156590	Glutathione conjugation	TAS
R-HSA-211859	Biological oxidations	TAS

Drugs and compounds information

ID	Drug Name	Action	PubMed
C026486	1,2,5,6-dibenzanthracene	GSTM1 protein affects the metabolism of [1,2,5,6-dibenzanthracene co-treated with Glutathione]	9403173
C012277	1,2-diamino-4-nitrobenzene	1,2-diamino-4-nitrobenzene results in increased expression of GSTM1 mRNA	17070881
C028328	1,2-dichloro-4-nitrobenzene	GSTM1 protein affects the metabolism of 1,2-dichloro-4-nitrobenzene	1859377
C028328	1,2-dichloro-4-nitrobenzene	GSTM1 protein affects the metabolism of 1,2-dichloro-4-nitrobenzene	7733673
C049325	1,2-dithiol-3-thione	1,2-dithiol-3-thione results in increased expression of GSTM1 mRNA	18367636
C049325	1,2-dithiol-3-thione	NFE2L2 gene mutant form inhibits the reaction [1,2-dithiol-3-thione results in increased expression of GSTM1 mRNA]	18367636
C049325	1,2-dithiol-3-thione	1,2-dithiol-3-thione results in increased expression of GSTM1 mRNA	19162173; 19695238;
C040756	1,2-naphthoquinone	GSTM1 protein results in decreased susceptibility to 1,2-naphthoquinone	10661898
C576882	1-(2-trifluoromethoxyphenyl)-2-nitroethanone	1-(2-trifluoromethoxyphenyl)-2-nitroethanone results in increased expression of GSTM1 protein	22527513
C031763	1,3-butadiene	GSTM1 gene polymorphism promotes the reaction [EPHX1 gene polymorphism results in increased susceptibility to 1,3-butadiene]	11238181
C031763	1,3-butadiene	1,3-butadiene results in increased expression of GSTM1 mRNA	29038090
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	[1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of NR1I3 protein] which results in increased expression of GSTM1 mRNA	22496397
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of GSTM1 mRNA	18723825; 22496397; 27413110; 28903501;
C028474	1,4-bis(2-(3,5-dichloropyridyloxy))benzene	NR1I3 protein affects the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of GSTM1 mRNA]	22496397
C097240	15-deoxy-delta(12,14)-prostaglandin J2	GSTM1 protein affects the metabolism of [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Glutathione]	14979731
C034086	1,5-naphthalenediamine	1,5-naphthalenediamine affects the expression of GSTM1 mRNA	17114358
C015262	1,6-hexamethylene diisocyanate	GSTM1 protein polymorphism results in increased susceptibility to 1,6-hexamethylene diisocyanate	11927838
C042630	1-chloro-2,4-dinitrobenzene-glutathione conjugate	GSTM1 protein affects the metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate	11684093
C033146	1-hydroxypyrene	GSTM1 gene polymorphism results in decreased secretion of 1-hydroxypyrene	21787681
D015655	1-Methyl-4-phenylpyridinium	U 0126 affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of GSTM1 mRNA]	12710931
D015655	1-Methyl-4-phenylpyridinium	1-Methyl-4-phenylpyridinium results in decreased expression of GSTM1 mRNA	16026605
D015058	1-Naphthylisothiocyanate	1-Naphthylisothiocyanate results in increased expression of GSTM1 mRNA	30723492
C035314	1-nitropropane	1-nitropropane results in decreased expression of GSTM1 mRNA	17070881
C477694	2,2',4,4',5-brominated diphenyl ether	2,2',4,4',5-brominated diphenyl ether results in increased expression of GSTM1 mRNA	19270788
C111120	2,3,3',4',5-pentachloro-4-hydroxybiphenyl	2,3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of GSTM1 mRNA	29788408
C014211	2,3,7,8-tetrachlorodibenzofuran	2,3,7,8-tetrachlorodibenzofuran affects the expression of GSTM1 mRNA	20702594
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of GSTM1 protein	23457121
C014024	2,4,5,2',4',5'-hexachlorobiphenyl	[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of GSTM1 mRNA	28433925
C010914	2,4-diaminotoluene	2,4-diaminotoluene results in increased expression of GSTM1 mRNA	17070881
C016403	2,4-dinitrotoluene	2,4-dinitrotoluene affects the expression of GSTM1 mRNA	21346803
C085911	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one	2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of GSTM1 mRNA	22406437
C009497	2-(4-toluidino)-6-naphthalenesulfonic acid	2-(4-toluidino)-6-naphthalenesulfonic acid binds to GSTM1 protein	7725348
C025235	2,6-diaminotoluene	2,6-diaminotoluene results in decreased expression of GSTM1 mRNA	17070881
C023514	2,6-dinitrotoluene	2,6-dinitrotoluene affects the expression of GSTM1 mRNA	21346803
D015073	2-Acetylaminofluorene	2-Acetylaminofluorene results in increased expression of GSTM1 mRNA	17070881
C099328	2-allylphenol	2-allylphenol results in decreased activity of GSTM1 protein	8620581
C049584	2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	GSTM1 gene polymorphism affects the susceptibility to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine	22564066
C036990	2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline	GSTM1 gene polymorphism affects the susceptibility to 2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline	22564066
C035208	2-amino-4,6-dinitrotoluene	2-amino-4,6-dinitrotoluene affects the expression of GSTM1 mRNA	21346803
C060533	2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine	2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of GSTM1 protein	17122891
C014706	2-nitro-4-phenylenediamine	2-nitro-4-phenylenediamine results in increased expression of GSTM1 mRNA	17070881
C016617	2-nitropropane	2-nitropropane results in increased expression of GSTM1 mRNA	17070881
C082398	2-S-glutathionylcaffeic acid	2-S-glutathionylcaffeic acid results in decreased activity of GSTM1 protein	8340025
C018855	2-tert-butylhydroquinone	2-tert-butylhydroquinone results in increased expression of GSTM1 protein	21443188
C016392	3,3'-diindolylmethane	3,3'-diindolylmethane results in decreased expression of GSTM1 mRNA	19770484
C016392	3,3'-diindolylmethane	[3,3'-diindolylmethane results in decreased expression of GSTM1 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct	19770484
C023035	3,4,5,3',4'-pentachlorobiphenyl	[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GSTM1 mRNA	24378064
C023035	3,4,5,3',4'-pentachlorobiphenyl	3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM1 mRNA	18723825
C023035	3,4,5,3',4'-pentachlorobiphenyl	3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of GSTM1 mRNA	23196670
C023035	3,4,5,3',4'-pentachlorobiphenyl	3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GSTM1 mRNA	20959002
C007430	3,4-dihydroxyphenylacetaldehyde	3,4-dihydroxyphenylacetaldehyde binds to GSTM1 protein	21238438
C050224	3,5,5-trimethylhexanoylferrocene	3,5,5-trimethylhexanoylferrocene results in increased expression of GSTM1 protein	22649188
C053603	3-methylpyridine	3-methylpyridine results in decreased expression of GSTM1 protein	7986210
C009505	4,4'-diaminodiphenylmethane	4,4'-diaminodiphenylmethane results in decreased expression of GSTM1 mRNA	18648102
C009505	4,4'-diaminodiphenylmethane	4,4'-diaminodiphenylmethane results in increased expression of GSTM1 mRNA	30723492
C005969	4,4'-diphenylmethane diisocyanate	GSTM1 protein polymorphism results in increased susceptibility to 4,4'-diphenylmethane diisocyanate	11927838
C028676	4-acetylaminofluorene	4-acetylaminofluorene results in increased expression of GSTM1 mRNA	17070881
C035207	4-amino-2,6-dinitrotoluene	4-amino-2,6-dinitrotoluene affects the expression of GSTM1 mRNA	21346803
C010407	4-chloronitrobenzene	GSTM1 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]	8867999
C010407	4-chloronitrobenzene	GSTM1 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]	8973562
C018511	4-dichlorobenzene	4-dichlorobenzene results in increased expression of GSTM1 mRNA	28541575
C027576	4-hydroxy-2-nonenal	GSTM1 protein affects the metabolism of 4-hydroxy-2-nonenal analog	11256969
C027576	4-hydroxy-2-nonenal	[GSTM1 protein binds to GSTM2 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog	11256969
C027576	4-hydroxy-2-nonenal	[GSTM1 protein binds to GSTM3 protein] which affects the metabolism of 4-hydroxy-2-nonenal analog	11256969
C027576	4-hydroxy-2-nonenal	4-hydroxy-2-nonenal results in increased expression of GSTM1 protein	12020353
C027576	4-hydroxy-2-nonenal	[GSTM1 protein co-treated with 4-hydroxy-2-nonenal] results in decreased abundance of Glutathione	21925487
C027576	4-hydroxy-2-nonenal	[GSTM1 protein co-treated with ABCC1 protein] results in increased susceptibility to 4-hydroxy-2-nonenal	21925487
C041594	4-nonylphenol	4-nonylphenol results in increased expression of GSTM1 mRNA	30612256
C570540	4-O-decyl-gabosine D	4-O-decyl-gabosine D inhibits the reaction [Glutathione binds to GSTM1 protein]	22085405
C002202	4-oxoretinoic acid	4-oxoretinoic acid results in decreased expression of GSTM1 mRNA	15982314
C099327	4-propylphenol	4-propylphenol results in decreased activity of GSTM1 protein	8620581
C029370	4-toluidine	4-toluidine results in increased expression of GSTM1 mRNA	27638505
C522589	5,6-dihydrocyclopenta-1,2-dithiole-3-thione	5,6-dihydrocyclopenta-1,2-dithiole-3-thione results in increased expression of GSTM1 mRNA	19695238
C544471	5-hydroxythalidomide	5-hydroxythalidomide binds to GSTM1 protein	27464947
C086396	5-S-glutathionyl-alpha-methyldopa	5-S-glutathionyl-alpha-methyldopa results in decreased activity of GSTM1 protein	8131222
C086394	5-S-glutathionyldopamine	5-S-glutathionyldopamine results in decreased activity of GSTM1 protein	8131222
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of GSTM1 mRNA	19150397
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	GSTM1 protein affects the metabolism of [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide co-treated with Glutathione]	9403173
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	GSTM1 protein affects the metabolism of and results in decreased activity of [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide co-treated with Glutathione]	11849043
C008450	7-methylguanine	GSTM1 gene polymorphism affects the susceptibility to and affects the metabolism of 7-methylguanine	15066569
C037112	9-deoxy-delta-9-prostaglandin D2	GSTM1 protein affects the metabolism of 9-deoxy-delta-9-prostaglandin D2	9084911
D000082	Acetaminophen	Acetaminophen results in decreased expression of GSTM1 mRNA	29067470
D000082	Acetaminophen	GSTM1 protein inhibits the reaction [[CYP2E1 protein co-treated with CYP1A2 protein] results in increased susceptibility to Acetaminophen]	28762043
D000082	Acetaminophen	Acetaminophen results in decreased expression of GSTM1 mRNA	16611625
D000082	Acetaminophen	[CTH gene mutant form results in increased susceptibility to Acetaminophen] which results in decreased expression of GSTM1 protein	25499718
D000082	Acetaminophen	GSTM1 gene mutant form inhibits the reaction [Acetaminophen results in increased phosphorylation of GSK3B protein]	22687999
D000082	Acetaminophen	GSTM1 gene mutant form inhibits the reaction [Acetaminophen results in increased phosphorylation of MAP2K4 protein]	22687999
D000082	Acetaminophen	GSTM1 results in increased susceptibility to Acetaminophen	22687999
D000082	Acetaminophen	Acetaminophen results in increased expression of GSTM1 mRNA	30723492
D000111	Acetylcysteine	Acetylcysteine inhibits the reaction [alpha-methylepinine results in increased expression of GSTM1 mRNA]	21871945
D000111	Acetylcysteine	[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTM1 mRNA	22129741
D020106	Acrylamide	[CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism] affects the metabolism of Acrylamide	19131562
D020106	Acrylamide	[CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the metabolism of Acrylamide	19131562
D020106	Acrylamide	GSTM1 gene polymorphism affects the metabolism of Acrylamide	19131562; 21402133;
D020106	Acrylamide	[GSTM1 gene polymorphism affects the metabolism of Acrylamide] which affects the chemical synthesis of N-acetyl-S-(2-carbamoylethyl)cysteine	21402133
D020106	Acrylamide	Acrylamide results in increased expression of GSTM1 mRNA	27836571; 28526328;
D020106	Acrylamide	Acrylamide results in increased expression of GSTM1 protein	28526328
D020106	Acrylamide	Acrylamide results in increased expression of GSTM1 mRNA	28959563
C109238	acyline	acyline results in decreased expression of GSTM1 mRNA	17510436
D016604	Aflatoxin B1	GSTM1 gene mutant form results in increased susceptibility to Aflatoxin B1	7892276
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of GSTM1 mRNA	19770486
D016604	Aflatoxin B1	Aflatoxin B1 results in increased expression of GSTM1 mRNA	23630614; 25378103;
C006426	aflatoxin B1-2,3-oxide	GSTM1 protein affects the metabolism of and results in decreased activity of aflatoxin B1-2,3-oxide	1638515
C052669	aflatoxin B1-bovine serum albumin	GSTM1 gene mutant form results in increased abundance of aflatoxin B1-bovine serum albumin	7892276
C072611	aflatoxin B1-DNA adduct	[3,3'-diindolylmethane results in decreased expression of GSTM1 mRNA] which results in increased abundance of aflatoxin B1-DNA adduct	19770484
C072611	aflatoxin B1-DNA adduct	GSTM1 gene polymorphism affects the abundance of aflatoxin B1-DNA adduct	20442190
D000348	Aflatoxins	GSTM1 gene polymorphism results in increased susceptibility to Aflatoxins	15734960
D000393	Air Pollutants	GSTM1 gene polymorphism affects the susceptibility to Air Pollutants	22732554
D000395	Air Pollutants, Occupational	GSTM1 gene polymorphism affects the susceptibility to Air Pollutants, Occupational	20723587
D000077556	Alitretinoin	Alitretinoin results in decreased expression of GSTM1 mRNA	15982314
C004471	allyl isothiocyanate	GSTM1 protein affects the metabolism of allyl isothiocyanate	7826396
C038491	allyl sulfide	allyl sulfide results in increased expression of GSTM1 mRNA	18723825
C038491	allyl sulfide	allyl sulfide results in increased expression of GSTM1 mRNA	19695238; 8627517;
C038491	allyl sulfide	allyl sulfide results in increased expression of GSTM1 protein	8627517
D000517	alpha-Chlorohydrin	alpha-Chlorohydrin analog results in increased expression of GSTM1 protein	26597043
C069512	alpha-methylepinine	Acetylcysteine inhibits the reaction [alpha-methylepinine results in increased expression of GSTM1 mRNA]	21871945
C069512	alpha-methylepinine	alpha-methylepinine results in increased expression of GSTM1 mRNA	21871945
C069512	alpha-methylepinine	sulforafan inhibits the reaction [alpha-methylepinine results in increased expression of GSTM1 mRNA]	21871945
D024502	alpha-Tocopherol	[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA]	22389237
C100057	ametryne	ametryne results in increased expression of GSTM1 mRNA	26310382
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of GSTM1 mRNA	16483693
C019257	angelica lactone	angelica lactone results in increased expression of GSTM1 protein	11309284
C000228	aristolochic acid I	aristolochic acid I results in increased expression of GSTM1 mRNA	17483316
D001151	Arsenic	GSTM1 gene mutant form results in decreased susceptibility to Arsenic	16353154
D001151	Arsenic	GSTM1 gene polymorphism affects the metabolism of and affects the susceptibility to Arsenic	17365577
D001151	Arsenic	GSTM1 gene polymorphism affects the methylation of Arsenic	25876999
D001151	Arsenic	GSTM1 gene SNP affects the metabolism of Arsenic	27327299
D001151	Arsenic	GSTM1 polymorphism affects the metabolism of Arsenic	17365577
D001151	Arsenic	GSTM1 protein affects the susceptibility to Arsenic	18053222
D001151	Arsenic	GSTM1 mutant form affects the metabolism of Arsenic	22136492
D000077237	Arsenic Trioxide	Arsenic Trioxide results in increased expression of GSTM1 mRNA	20458559; 22521957;
D000077237	Arsenic Trioxide	GSTM1 protein results in decreased susceptibility to Arsenic Trioxide	20067466
C015001	arsenite	arsenite results in increased expression of GSTM1 mRNA	18929588
D001194	Asbestos	GSTM1 gene polymorphism affects the susceptibility to Asbestos	20847076
D001194	Asbestos	GSTM1 gene polymorphism results in increased susceptibility to Asbestos	18420450
D001205	Ascorbic Acid	GSTM1 affects the susceptibility to Ascorbic Acid deficiency	19710200
D001205	Ascorbic Acid	GSTM1 gene polymorphism affects the susceptibility to [Ascorbic Acid co-treated with tocotrienol, alpha]	15668500
D001205	Ascorbic Acid	Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of GSTM1 mRNA]	23470461
D001205	Ascorbic Acid	Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSTM1 mRNA]	23470461
D001241	Aspirin	GSTM1 mutant form affects the susceptibility to Aspirin	16433794
D001280	Atrazine	[Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in increased expression of GSTM1 mRNA	22515965
D001379	Azathioprine	GSTM1 gene polymorphism affects the susceptibility to Azathioprine	17206640
D001379	Azathioprine	GSTM1 protein affects the metabolism of Azathioprine	18155239; 20434437;
D001554	Benzene	GSTM1 gene mutant form affects the susceptibility to Benzene	14694614
D001554	Benzene	GSTM1 gene polymorphism affects the reaction [GSTT1 gene polymorphism affects the reaction [NQO1 gene SNP results in increased susceptibility to Benzene]]	17178637
D001554	Benzene	GSTM1 gene polymorphism affects the susceptibility to Benzene	15226677
D001554	Benzene	GSTM1 gene polymorphism results in increased susceptibility to Benzene	15226677; 15748501;
D001554	Benzene	GSTM1 protein affects the metabolism of Benzene	10511268; 15226677;
D001554	Benzene	[GSTM1 protein affects the metabolism of Benzene] which affects the abundance of muconic acid	10511268
D001554	Benzene	GSTM1 protein affects the susceptibility to Benzene	29204680
D001554	Benzene	GSTM1 protein results in increased metabolism of Benzene	17885617
D001554	Benzene	GSTM1 gene polymorphism affects the susceptibility to Benzene	18848868
C023372	benzene oxide	GSTM1 protein affects the metabolism of benzene oxide	22153878
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of GSTM1 mRNA	17253728
D001564	Benzo(a)pyrene	[Docosahexaenoic Acids co-treated with Benzo(a)pyrene] results in decreased expression of GSTM1 protein	25956473
D001564	Benzo(a)pyrene	GSTM1 gene polymorphism affects the susceptibility to Benzo(a)pyrene	15471894
D001564	Benzo(a)pyrene	GSTM1 gene polymorphism results in increased susceptibility to Benzo(a)pyrene	7728947
D001564	Benzo(a)pyrene	GSTM1 protein affects the metabolism of [Benzo(a)pyrene co-treated with Glutathione]	9403173
D001564	Benzo(a)pyrene	GSTM1 protein inhibits the reaction [CYP1A1 protein promotes the reaction [Benzo(a)pyrene results in increased mutagenesis of HPRT1 gene]]	17525473
D001564	Benzo(a)pyrene	GSTM1 protein inhibits the reaction [CYP1A1 protein results in increased susceptibility to Benzo(a)pyrene]	17525473
D001564	Benzo(a)pyrene	GSTM1 protein polymorphism affects the metabolism of and affects the activity of Benzo(a)pyrene	15298956
D001564	Benzo(a)pyrene	GSTM1 protein results in decreased susceptibility to Benzo(a)pyrene metabolite	17525473
D001564	Benzo(a)pyrene	AHR protein promotes the reaction [Benzo(a)pyrene results in increased expression of GSTM1 mRNA]	15034205
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased activity of GSTM1 protein	30938511
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of GSTM1 mRNA	15034205; 19770486; 20127859; 21569818; 22228805;
D001564	Benzo(a)pyrene	[lipopolysaccharide, E coli O55-B5 co-treated with Benzo(a)pyrene] affects the expression of GSTM1 mRNA	28987381
C017228	benzo(a)pyrene 7,8-dihydrodiol	GSTM1 protein inhibits the reaction [CYP1A1 protein promotes the reaction [benzo(a)pyrene 7,8-dihydrodiol results in increased mutagenesis of HPRT1 gene]]	17525473
C006703	benzo(b)fluoranthene	[Docosahexaenoic Acids co-treated with benzo(b)fluoranthene] results in decreased expression of GSTM1 protein	25956473
C105430	benzofuran	benzofuran affects the expression of GSTM1 mRNA	17114358
C089231	benzo(g)chrysene-11,12-dihydrodiol-13,14-epoxide	GSTM1 protein results in increased glutathionylation of benzo(g)chrysene-11,12-dihydrodiol-13,14-epoxide	9308905
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in decreased expression of GSTM1 mRNA	17253728
C022921	benzo(k)fluoranthene	[Docosahexaenoic Acids co-treated with benzo(k)fluoranthene] results in decreased expression of GSTM1 protein	25956473
C005465	benzothiazole	benzothiazole results in increased expression of GSTM1 mRNA	8951341
C012771	benzotriazole	benzotriazole results in increased expression of GSTM1 mRNA	8951341
C006710	benzotriphenylene	benzotriphenylene results in decreased expression of GSTM1 mRNA	17253728
D001583	Benzoxazoles	Benzoxazoles results in increased expression of GSTM1 mRNA	8951341
C031403	benzyl isothiocyanate	GSTM1 protein affects the metabolism of benzyl isothiocyanate	7826396
C072553	benzyloxycarbonylleucyl-leucyl-leucine aldehyde	benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of GSTM1 mRNA	20061341
C038328	BEP protocol	BEP protocol results in increased expression of GSTM1 mRNA	18987330; 23200778;
C023888	beta-hexachlorocyclohexane	GSTM1 gene polymorphism affects the susceptibility to beta-hexachlorocyclohexane	22310945
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in increased expression of GSTM1 mRNA	18723825
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in increased expression of GSTM1 mRNA	22687991
D019324	beta-Naphthoflavone	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA	18164116; 20045035;
D019324	beta-Naphthoflavone	isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA]	20045035
D024503	beta-Tocopherol	[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA]	22389237
C099952	bifenthrin	bifenthrin results in increased expression of GSTM1 mRNA	26071804
D001663	Bilirubin	Bilirubin results in decreased expression of GSTM1 mRNA	20196124
C006780	bisphenol A	bisphenol A results in increased expression of GSTM1 mRNA	30612256
C006780	bisphenol A	GSTM1 protein results in increased susceptibility to bisphenol A	27491884
C006780	bisphenol A	bisphenol A results in increased expression of GSTM1 mRNA	30566610
C006780	bisphenol A	[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of GSTM1 mRNA	28433925
C006780	bisphenol A	bisphenol A affects the expression of GSTM1 mRNA	25181051; 30903817;
C006780	bisphenol A	bisphenol A results in decreased expression of GSTM1 mRNA	29097150
C006780	bisphenol A	bisphenol A results in increased expression of GSTM1 mRNA	27208089
D001761	Bleomycin	Bleomycin results in decreased expression of GSTM1 protein	25933445
C584056	BMS-764459	BMS-764459 results in increased expression of GSTM1 mRNA	23831372
C032036	bromobenzene	bromobenzene metabolite binds to GSTM1 protein	17305373
C032036	bromobenzene	bromobenzene results in increased expression of GSTM1 mRNA	12628495
C026405	bromotriethylstannane	bromotriethylstannane inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]	7733673
C026405	bromotriethylstannane	bromotriethylstannane results in decreased activity of GSTM1 protein	7733673
D002066	Busulfan	GSTM1 gene polymorphism affects the abundance of Busulfan	20672371
D002066	Busulfan	GSTM1 gene polymorphism affects the susceptibility to Busulfan	15142875; 19584821;
D002066	Busulfan	[GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the metabolism of Busulfan	21215809
D002066	Busulfan	GSTM1 protein affects the metabolism of Busulfan	8886613
D002066	Busulfan	[GSTM1 protein co-treated with CYP2C9 protein] results in increased susceptibility to [Busulfan co-treated with Cyclophosphamide]	28744217
D019328	Buthionine Sulfoximine	Buthionine Sulfoximine results in increased expression of GSTM1 mRNA	15878706
D002083	Butylated Hydroxyanisole	Butylated Hydroxyanisole results in increased activity of GSTM1 protein	11895860
D002083	Butylated Hydroxyanisole	Butylated Hydroxyanisole results in increased expression of GSTM1 mRNA	18723825
D002083	Butylated Hydroxyanisole	Butylated Hydroxyanisole results in increased expression of GSTM1 protein	11309284; 11991805; 2597111; 29086419;
D002083	Butylated Hydroxyanisole	NFE2L2 protein affects the reaction [Butylated Hydroxyanisole results in increased activity of GSTM1 protein]	11895860
D002085	Butylhydroxybutylnitrosamine	Butylhydroxybutylnitrosamine results in decreased expression of GSTM1 protein	24998975
C018475	butyraldehyde	butyraldehyde results in increased expression of GSTM1 mRNA	26079696
D020148	Butyric Acid	Butyric Acid results in increased expression of GSTM1 mRNA	12800193
D002101	Cacodylic Acid	Cacodylic Acid results in increased expression of GSTM1 mRNA	16436460
D002101	Cacodylic Acid	Cacodylic Acid results in increased expression of GSTM1 protein	16436460
D002104	Cadmium	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GSTM1 protein	30359721
D002104	Cadmium	Cadmium results in increased expression of GSTM1 mRNA	24067728
C028031	cadmium acetate	cadmium acetate affects the expression of GSTM1 mRNA	16249259
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of GSTM1 mRNA	19031917
D019256	Cadmium Chloride	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GSTM1 protein	30359721
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of GSTM1 mRNA	25993096
C053400	cafestol	[cafestol co-treated with kahweol] results in increased expression of GSTM1 protein	11346484
C053400	cafestol	[cafestol co-treated with kahweol palmitate] results in increased expression of GSTM1 protein	11309284
C040048	caffeic acid	caffeic acid results in decreased activity of GSTM1 protein	8340025
D002117	Calcitriol	Calcitriol results in increased expression of GSTM1 mRNA	21592394
D002117	Calcitriol	[Testosterone co-treated with Calcitriol] results in increased expression of GSTM1 mRNA	21592394
D002185	Cannabidiol	Cannabidiol results in increased expression of GSTM1 mRNA	21542829
D002220	Carbamazepine	GSTM1 gene mutant form results in increased susceptibility to Carbamazepine	17465707
D002220	Carbamazepine	Carbamazepine results in increased expression of GSTM1 mRNA	17381134
D002244	Carbon	GSTM1 gene SNP affects the susceptibility to Carbon	21138591
D002246	Carbon Disulfide	GSTM1 gene polymorphism affects the metabolism of Carbon Disulfide	17333241
D002251	Carbon Tetrachloride	[Carbon Tetrachloride co-treated with Tamoxifen] affects the expression of GSTM1 mRNA	29974145
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of GSTM1 protein	15650968
D002251	Carbon Tetrachloride	[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 protein	12725062
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in decreased activity of GSTM1 protein polymorphism	12611589
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of GSTM1 mRNA	31150632
D002251	Carbon Tetrachloride	GSTM1 protein polymorphism affects the susceptibility to Carbon Tetrachloride	12611589
D002251	Carbon Tetrachloride	schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of GSTM1 mRNA]	31150632
D002251	Carbon Tetrachloride	Tea inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 protein]	12725062
D002330	Carmustine	GSTM1 gene affects the susceptibility to Carmustine	16087946
D002330	Carmustine	GSTM1 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]	16087946
D002330	Carmustine	GSTM1 protein results in decreased susceptibility to Carmustine	20067466
D002509	Cephaloridine	Cephaloridine results in increased expression of GSTM1 mRNA	18172885; 18500788;
D002635	Chenodeoxycholic Acid	Chenodeoxycholic Acid binds to and results in decreased activity of GSTM1 protein	3954743
D002699	Chlorambucil	GSTM1 protein results in decreased susceptibility to Chlorambucil	15044619; 20067466;
D020111	Chlorodiphenyl (54% Chlorine)	Chlorodiphenyl (54% Chlorine) results in increased expression of GSTM1 mRNA	18178546
D002737	Chloroprene	Chloroprene results in increased expression of GSTM1 mRNA	23125180
D004390	Chlorpyrifos	[Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in increased expression of GSTM1 mRNA	22515965
D004390	Chlorpyrifos	Chlorpyrifos affects the expression of GSTM1 mRNA	19440498
D004390	Chlorpyrifos	Chlorpyrifos results in increased expression of GSTM1 mRNA	17452286
D019826	Cholic Acid	Cholic Acid binds to and results in decreased activity of GSTM1 protein	3954743
D002857	Chromium	[chromous chloride results in increased abundance of Chromium] which results in decreased expression of GSTM1 protein	30359721
C074702	chromium hexavalent ion	Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of GSTM1 mRNA]	23470461
C074702	chromium hexavalent ion	chromium hexavalent ion results in decreased expression of GSTM1 mRNA	23470461
C017133	chromous chloride	[chromous chloride results in increased abundance of Chromium] which results in decreased expression of GSTM1 protein	30359721
C031180	chrysene	GSTM1 protein affects the metabolism of [chrysene co-treated with Glutathione]	9403173
C021977	chrysene,2-diol-3,4-epoxide-1	GSTM1 protein results in increased glutathionylation of chrysene,2-diol-3,4-epoxide-1	9308905
C012842	Cibacron Blue F 3GA	Cibacron Blue F 3GA inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]	7733673
C012842	Cibacron Blue F 3GA	Cibacron Blue F 3GA results in decreased activity of GSTM1 protein	7733673
C012843	cinnamic aldehyde	cinnamic aldehyde results in increased expression of GSTM1 mRNA	28219650
C019304	ciprofibrate	ciprofibrate results in decreased expression of GSTM1 mRNA	7676460
D002945	Cisplatin	GSTM1 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]	16087946
D002945	Cisplatin	GSTM1 gene polymorphism affects the susceptibility to [Paclitaxel co-treated with Cisplatin]	12851839
D002945	Cisplatin	GSTM1 protein affects the susceptibility to Cisplatin	16217747; 22085405;
D002945	Cisplatin	Cisplatin results in increased expression of GSTM1 mRNA	21151649
D002994	Clofibrate	Clofibrate results in decreased expression of GSTM1 mRNA	19952500
D002994	Clofibrate	Clofibrate results in increased expression of GSTM1 mRNA	22496397
D002994	Clofibrate	Clofibrate results in decreased expression of GSTM1 mRNA	11328961
D002994	Clofibrate	Clofibrate results in decreased expression of GSTM1 protein	16470657
D002994	Clofibrate	GSTM1 affects the susceptibility to Clofibrate	16800819
D003024	Clozapine	GSTM1 protein results in decreased activity of Clozapine	20849150
D003024	Clozapine	GSTM1 protein results in increased glutathionylation of Clozapine	20849150
D003024	Clozapine	Clozapine results in increased expression of GSTM1 mRNA	15860345
D003300	Copper	[ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of GSTM1 mRNA	15467011
D003300	Copper	Copper results in increased expression of GSTM1 mRNA	30556269
C515714	copper (N-2-hydroxyacetophenone)glycinate	copper (N-2-hydroxyacetophenone)glycinate results in decreased expression of GSTM1 protein	16289015
C515714	copper (N-2-hydroxyacetophenone)glycinate	[copper (N-2-hydroxyacetophenone)glycinate results in decreased expression of GSTM1 protein] which results in increased susceptibility to Doxorubicin	16289015
D003407	Creosote	Creosote results in increased expression of GSTM1 mRNA	19389177
D003436	Croton Oil	Croton Oil results in decreased expression of GSTM1 mRNA	21404309
C007164	cumene hydroperoxide	GSTM1 protein affects the metabolism of cumene hydroperoxide	10973735
C007164	cumene hydroperoxide	GSTM1 protein affects the metabolism of cumene hydroperoxide	11684093
D003471	Cuprizone	Cuprizone results in increased expression of GSTM1 mRNA	26577399
C057862	cyanoginosin LR	GSTM1 protein results in increased glutathionylation of and affects the susceptibility to cyanoginosin LR	21504230
C057862	cyanoginosin LR	cyanoginosin LR results in decreased expression of GSTM1 mRNA	17383702
C057862	cyanoginosin LR	cyanoginosin LR results in increased expression of GSTM1 mRNA	17654400
D003520	Cyclophosphamide	GSTM1 gene affects the susceptibility to [Carmustine co-treated with Cyclophosphamide co-treated with Cisplatin]	16087946
D003520	Cyclophosphamide	[GSTM1 protein co-treated with CYP2C9 protein] results in increased susceptibility to [Busulfan co-treated with Cyclophosphamide]	28744217
C093628	cyproconazole	cyproconazole results in increased expression of GSTM1 mRNA	22334560
C093628	cyproconazole	cyproconazole results in increased expression of GSTM1 mRNA	25182419
D003545	Cysteine	Cysteine affects the expression of GSTM1 mRNA	11040448
D003561	Cytarabine	GSTM1 gene polymorphism affects the susceptibility to Cytarabine	15713801
D003630	Daunorubicin	GSTM1 gene polymorphism affects the susceptibility to Daunorubicin	15713801
C010902	decabromobiphenyl ether	decabromobiphenyl ether results in increased expression of GSTM1 mRNA	19270788
C479072	delta-tocopherol	[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA]	22389237
D003907	Dexamethasone	GSTM1 protein inhibits the reaction [Dexamethasone results in increased phosphorylation of BCL2L11 protein]	20067466
D003907	Dexamethasone	GSTM1 protein results in decreased susceptibility to Dexamethasone	20067466
D003907	Dexamethasone	Dexamethasone results in increased expression of GSTM1 mRNA	21041162; 22733784;
D003907	Dexamethasone	Dexamethasone results in increased expression of GSTM1 mRNA	11328961; 1394205;
D003976	Diazinon	Diazinon results in increased expression of GSTM1 mRNA	17452286
C041517	dibenzo(a,l)pyrene	GSTM1 protein affects the metabolism of and results in decreased activity of [dibenzo(a,l)pyrene co-treated with Glutathione]	11849043
C061481	dibenzoylmethane	dibenzoylmethane results in increased expression of GSTM1 mRNA	17942926
C061481	dibenzoylmethane	[sulforafan co-treated with dibenzoylmethane] results in increased expression of GSTM1 mRNA	17942926
D003999	Dichloroacetic Acid	Dichloroacetic Acid results in increased expression of GSTM1 mRNA	28962523
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in increased expression of GSTM1 mRNA	29554563
D004008	Diclofenac	Diclofenac results in decreased activity of GSTM1 protein	27183920
D004008	Diclofenac	Diclofenac results in decreased expression of GSTM1 mRNA	26934552
C121718	dicyclanil	dicyclanil results in increased expression of GSTM1 mRNA	15664270
C036042	dicyclohexyl phthalate	dicyclohexyl phthalate results in increased expression of GSTM1 mRNA	26924002
D004041	Dietary Fats	Dietary Fats affects the expression of GSTM1 mRNA	19680557
D004041	Dietary Fats	[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of GSTM1 mRNA	28433925
D004041	Dietary Fats	[Dietary Fats co-treated with Thioctic Acid] results in increased expression of GSTM1 mRNA	18367378
D004041	Dietary Fats	Dietary Fats results in decreased expression of GSTM1 mRNA	25016146
D004041	Dietary Fats	Dietary Fats results in increased expression of GSTM1 mRNA	30120929
D004042	Dietary Fats, Unsaturated	[perfluorooctanoic acid co-treated with Dietary Fats, Unsaturated] results in increased expression of GSTM1 mRNA	23626681
D019422	Dietary Sucrose	[Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of GSTM1 mRNA	28433925
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of GSTM1 mRNA	19245819; 19850644;
D004051	Diethylhexyl Phthalate	PPARA protein inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GSTM1 mRNA]	19850644
D004051	Diethylhexyl Phthalate	[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of GSTM1 mRNA	28433925
C014476	diethyl maleate	diethyl maleate results in decreased expression of GSTM1 protein	21161181
D004052	Diethylnitrosamine	[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of GSTM1 protein	23457121
D004052	Diethylnitrosamine	[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 protein	12725062
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA	18164116; 20045035;
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM1 mRNA	18544905
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM1 mRNA	18544905
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA	20033131
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of GSTM1 mRNA	20033131
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of GSTM1 mRNA	20033131
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of GSTM1 mRNA	23830814
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of GSTM1 mRNA	23830814; 28943392;
D004052	Diethylnitrosamine	[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTM1 mRNA	22129741
D004052	Diethylnitrosamine	[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GSTM1 mRNA	22129741
D004052	Diethylnitrosamine	isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA]	20045035
D004052	Diethylnitrosamine	[oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTM1 mRNA	18754104
D004052	Diethylnitrosamine	[Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of GSTM1 protein	20935162
D004052	Diethylnitrosamine	Tea inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 protein]	12725062
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of GSTM1 mRNA	21041162
C015835	dimethyl-4-toluidine	dimethyl-4-toluidine results in increased expression of GSTM1 mRNA	27638505
C024629	dimethyl phthalate	dimethyl phthalate results in increased expression of GSTM1 mRNA	26924002
D004121	Dimethyl Sulfoxide	Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTM1 protein]	12370186
D004137	Dinitrochlorobenzene	GSTM1 protein affects the metabolism of Dinitrochlorobenzene	14508638
D004137	Dinitrochlorobenzene	GSTM1 protein affects the metabolism of Dinitrochlorobenzene	9571047
D004137	Dinitrochlorobenzene	Dinitrochlorobenzene binds to GSTM1 protein	22085405
D004137	Dinitrochlorobenzene	GSTM1 protein affects the metabolism of Dinitrochlorobenzene	3570286; 9545290;
D004137	Dinitrochlorobenzene	GSTM1 protein results in increased glutathionylation of Dinitrochlorobenzene	28762043
D004137	Dinitrochlorobenzene	Dinitrochlorobenzene affects the expression of GSTM1 mRNA	28219650
D004137	Dinitrochlorobenzene	Dinitrochlorobenzene results in decreased expression of GSTM1 mRNA	21404309
D004137	Dinitrochlorobenzene	GSTM1 protein affects the metabolism of Dinitrochlorobenzene	12069689
D004137	Dinitrochlorobenzene	bromotriethylstannane inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]	7733673
D004137	Dinitrochlorobenzene	Cibacron Blue F 3GA inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]	7733673
D004137	Dinitrochlorobenzene	Hemin inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]	7733673
D004137	Dinitrochlorobenzene	Sulfobromophthalein inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]	7733673
D004137	Dinitrochlorobenzene	triphenyltin chloride inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]	7733673
D004137	Dinitrochlorobenzene	GSTM1 protein affects the metabolism of Dinitrochlorobenzene	11368767
D004137	Dinitrochlorobenzene	GSTM1 protein affects the metabolism of [Dinitrochlorobenzene analog co-treated with Glutathione]	8867999
D004137	Dinitrochlorobenzene	GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione]	2375757
D004137	Dinitrochlorobenzene	GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]	2375757
D004137	Dinitrochlorobenzene	GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]	2904809
C051904	dinophysistoxin 1	dinophysistoxin 1 results in increased expression of GSTM1 mRNA	28939011
D004147	Dioxins	GSTM1 gene mutant form results in increased susceptibility to Dioxins	27939992
D004178	Diquat	Diquat results in decreased expression of GSTM1 mRNA	7676460
D004050	Ditiocarb	Ditiocarb binds to and results in decreased activity of GSTM1 protein	6095330
D004237	Diuron	Diuron results in increased expression of GSTM1 mRNA	21551480
D004281	Docosahexaenoic Acids	[Docosahexaenoic Acids co-treated with Benzo(a)pyrene] results in decreased expression of GSTM1 protein	25956473
D004281	Docosahexaenoic Acids	[Docosahexaenoic Acids co-treated with benzo(b)fluoranthene] results in decreased expression of GSTM1 protein	25956473
D004281	Docosahexaenoic Acids	[Docosahexaenoic Acids co-treated with benzo(k)fluoranthene] results in decreased expression of GSTM1 protein	25956473
D004281	Docosahexaenoic Acids	[Docosahexaenoic Acids co-treated with pyrene] results in decreased expression of GSTM1 protein	25956473
D004298	Dopamine	Dopamine analog results in decreased activity of GSTM1 protein	8131222
D004317	Doxorubicin	[copper (N-2-hydroxyacetophenone)glycinate results in decreased expression of GSTM1 protein] which results in increased susceptibility to Doxorubicin	16289015
D004317	Doxorubicin	Doxorubicin results in increased expression of GSTM1 mRNA	16243910
D004317	Doxorubicin	GSTM1 protein results in decreased susceptibility to Doxorubicin	16289015
D004317	Doxorubicin	Doxorubicin results in increased oxidation of GSTM1 protein	28818578
D060766	Drinking Water	Drinking Water results in increased expression of GSTM1 mRNA	19444861
D013759	Dronabinol	Dronabinol results in increased expression of GSTM1 mRNA	21542829
C509867	E804 bisindole	E804 bisindole results in decreased expression of GSTM1 mRNA	23107598
C509867	E804 bisindole	Lipopolysaccharides inhibits the reaction [E804 bisindole results in decreased expression of GSTM1 mRNA]	23107598
C042986	ebselen	ebselen binds to and results in decreased activity of [GSTM1 protein binds to GSTM2 protein]	8147899
D004726	Endosulfan	[Atrazine co-treated with Chlorpyrifos co-treated with Endosulfan] results in increased expression of GSTM1 mRNA	22515965
D004726	Endosulfan	Endosulfan results in increased expression of GSTM1 mRNA	29391264
D004785	Environmental Pollutants	Environmental Pollutants results in increased expression of GSTM1 mRNA	12655031
D004785	Environmental Pollutants	GSTM1 gene polymorphism affects the susceptibility to Environmental Pollutants	24036326
D004811	Epichlorohydrin	GSTM1 gene polymorphism affects the susceptibility to Epichlorohydrin	15091291
C045651	epigallocatechin gallate	epigallocatechin gallate results in increased expression of GSTM1 mRNA	25585349
C109476	epoxiconazole	epoxiconazole results in increased expression of GSTM1 mRNA	22334560
C109476	epoxiconazole	epoxiconazole results in increased expression of GSTM1 mRNA	25182419
C073539	erucin	erucin results in increased expression of GSTM1 protein	18823965
D004958	Estradiol	[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA]	22389237
D004958	Estradiol	Estradiol affects the expression of GSTM1 mRNA	22389237
D004958	Estradiol	Estradiol results in decreased expression of GSTM1 mRNA	31119341
D002393	Estrogens, Catechol	GSTM1 protein affects the metabolism of Estrogens, Catechol metabolite	15455371
D004976	Ethacrynic Acid	GSTM1 protein affects the metabolism of Ethacrynic Acid	12069689
D000431	Ethanol	GSTM1 gene mutant form affects the susceptibility to Ethanol	20171022
D000431	Ethanol	GSTM1 gene polymorphism affects the susceptibility to Ethanol	15932176
D000431	Ethanol	Ethanol results in increased expression of GSTM1 mRNA	30319688
D000431	Ethanol	Ethanol results in increased expression of GSTM1 mRNA	23273579
D004997	Ethinyl Estradiol	Ethinyl Estradiol affects the expression of GSTM1 mRNA	17351261
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of GSTM1 mRNA	15834898
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of GSTM1 mRNA	23129252
D005015	Ethoxyquin	Ethoxyquin results in increased expression of GSTM1 mRNA	18723825
D005015	Ethoxyquin	Ethoxyquin results in increased expression of GSTM1 protein	11309284
D005015	Ethoxyquin	Ethoxyquin results in increased expression of GSTM1 mRNA	19695238
D005015	Ethoxyquin	Ethoxyquin results in increased expression of GSTM1 protein	8198522
D005034	Ethylmercuric Chloride	Ethylmercuric Chloride results in decreased activity of GSTM1 protein	1793546
D005047	Etoposide	GSTM1 gene polymorphism affects the susceptibility to Etoposide	15713801
D005054	Eugenol	Eugenol analog results in decreased activity of GSTM1 protein	8620581
C436526	EUK-189	EUK-189 inhibits the reaction [SOD2 gene mutant form results in increased expression of GSTM1 mRNA]	15964507
D005227	Fatty Acids	Fatty Acids binds to and results in increased activity of GSTM1 protein	2277038
D015525	Fatty Acids, Omega-3	GSTM1 gene polymorphism affects the susceptibility to Fatty Acids, Omega-3	15256483
D000078328	Felbamate	Felbamate results in increased expression of GSTM1 mRNA	17381134
C540355	fenamidone	fenamidone results in increased expression of GSTM1 mRNA	27029645
C540355	fenamidone	sulforafan inhibits the reaction [fenamidone results in increased expression of GSTM1 mRNA]	27029645
D017313	Fenretinide	Fenretinide results in increased expression of GSTM1 mRNA	28973697
D018120	Finasteride	Finasteride results in increased expression of GSTM1 mRNA	24136188
C082360	fipronil	fipronil results in increased expression of GSTM1 mRNA	23962444
D015725	Fluconazole	Fluconazole results in increased expression of GSTM1 mRNA	16730040
D005485	Flutamide	Flutamide results in increased expression of GSTM1 mRNA	24136188
C056933	fumonisin B1	fumonisin B1 results in increased expression of GSTM1 mRNA	16221962
C039281	furan	furan results in increased expression of GSTM1 mRNA	20194422; 24183702;
C039281	furan	furan results in increased expression of GSTM1 mRNA	25539665; 26194646;
D000077206	Gabapentin	Gabapentin results in increased expression of GSTM1 mRNA	17381134
D024504	gamma-Tocopherol	gamma-Tocopherol results in increased expression of GSTM1 mRNA	19115203
D024504	gamma-Tocopherol	gamma-Tocopherol results in increased expression of GSTM1 protein	19115203
D024504	gamma-Tocopherol	[alpha-Tocopherol co-treated with beta-Tocopherol co-treated with gamma-Tocopherol co-treated with delta-tocopherol] affects the reaction [Estradiol affects the expression of GSTM1 mRNA]	22389237
C007835	geniposide	geniposide results in increased expression of GSTM1 mRNA	14646352
C007835	geniposide	geniposide results in increased expression of GSTM1 protein	14646352
D005839	Gentamicins	Gentamicins results in increased expression of GSTM1 mRNA	22061828
D005961	Glucosinolates	Glucosinolates results in increased expression of GSTM1 protein	15570060
D005978	Glutathione	GSTM1 protein affects the metabolism of Glutathione	10973735
D005978	Glutathione	4-O-decyl-gabosine D inhibits the reaction [Glutathione binds to GSTM1 protein]	22085405
D005978	Glutathione	Glutathione binds to GSTM1 protein	22085405
D005978	Glutathione	GSTM1 gene mutant form results in decreased abundance of Glutathione	25420021
D005978	Glutathione	GSTM1 protein affects the metabolism of [1,2,5,6-dibenzanthracene co-treated with Glutathione]	9403173
D005978	Glutathione	GSTM1 protein affects the metabolism of [15-deoxy-delta(12,14)-prostaglandin J2 co-treated with Glutathione]	14979731
D005978	Glutathione	GSTM1 protein affects the metabolism of [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide co-treated with Glutathione]	9403173
D005978	Glutathione	GSTM1 protein affects the metabolism of and results in decreased activity of [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide co-treated with Glutathione]	11849043
D005978	Glutathione	GSTM1 protein affects the metabolism of and results in decreased activity of [dibenzo(a,l)pyrene co-treated with Glutathione]	11849043
D005978	Glutathione	GSTM1 protein affects the metabolism of [Benzo(a)pyrene co-treated with Glutathione]	9403173
D005978	Glutathione	GSTM1 protein affects the metabolism of [chrysene co-treated with Glutathione]	9403173
D005978	Glutathione	GSTM1 protein affects the metabolism of Glutathione	7826396; 8886613; 9084911; 9545290;
D005978	Glutathione	GSTM1 protein affects the metabolism of [hydratropic aldehyde co-treated with Glutathione]	11368548
D005978	Glutathione	[GSTM1 protein co-treated with 4-hydroxy-2-nonenal] results in decreased abundance of Glutathione	21925487
D005978	Glutathione	GSTM1 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]	8867999
D005978	Glutathione	GSTM1 protein affects the metabolism of [Dinitrochlorobenzene analog co-treated with Glutathione]	8867999
D005978	Glutathione	GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione]	2375757
D005978	Glutathione	GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]	2375757
D005978	Glutathione	Glutathione analog binds to and results in decreased activity of GSTM1 protein	1883342
D005978	Glutathione	Glutathione deficiency results in increased expression of GSTM1 mRNA	15345336
D005978	Glutathione	GSTM1 protein affects the metabolism of [4-chloronitrobenzene analog co-treated with Glutathione]	8973562
D005978	Glutathione	GSTM1 protein affects the metabolism of [Dinitrochlorobenzene co-treated with Glutathione analog]	2904809
D005978	Glutathione	GSTM1 protein affects the metabolism of Glutathione	6095330
D005978	Glutathione	GSTM1 protein affects the metabolism of [styrene oxide co-treated with Glutathione]	2604743
C071834	glycidamide	[CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism] affects the abundance of glycidamide	19131562
C071834	glycidamide	[CYP2E1 gene polymorphism co-treated with GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the abundance of glycidamide	19131562
C071834	glycidamide	GSTM1 gene polymorphism affects the abundance of glycidamide	19131562
D006016	Glycolates	Glycolates analog binds to and results in decreased activity of GSTM1 protein	6686184
C412815	GW 4064	GW 4064 results in increased expression of GSTM1 mRNA	26655953
D006220	Haloperidol	Haloperidol results in increased expression of GSTM1 mRNA	15860345
D006427	Hemin	Hemin inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]	7733673
D006427	Hemin	Hemin results in decreased activity of GSTM1 protein	7733673
D006540	Herbicides	Herbicides binds to and results in decreased activity of GSTM1 protein	6686184
D006581	Hexachlorobenzene	Hexachlorobenzene results in decreased expression of GSTM1 mRNA	15159207
C001335	hexachlorobutadiene	hexachlorobutadiene results in increased expression of GSTM1 protein	21259293; 21905055;
C033550	hexylglutathione	hexylglutathione binds to and results in decreased activity of GSTM1 protein	9571047
C013026	hydratropic aldehyde	GSTM1 protein affects the metabolism of [hydratropic aldehyde co-treated with Glutathione]	11368548
C013026	hydratropic aldehyde	GSTM1 protein results in decreased activity of hydratropic aldehyde	11368548
C013026	hydratropic aldehyde	hydratropic aldehyde results in decreased activity of GSTM1 protein	11368548
C029424	hydrazine	GSTM1 gene mutant form results in increased abundance of hydrazine	18544910
D006843	Hydrocarbons, Chlorinated	GSTM1 gene polymorphism affects the susceptibility to Hydrocarbons, Chlorinated	26479327
D006851	Hydrochloric Acid	Hydrochloric Acid results in increased expression of GSTM1 mRNA	29618784
D006851	Hydrochloric Acid	NFE2L2 gene mutant form inhibits the reaction [Hydrochloric Acid results in increased expression of GSTM1 mRNA]	29618784
D006861	Hydrogen Peroxide	GSTM1 protein results in decreased susceptibility to Hydrogen Peroxide	10661898
D006861	Hydrogen Peroxide	[HP gene polymorphism co-treated with GSTM1 gene polymorphism] affects the susceptibility to Hydrogen Peroxide	20444272
C031927	hydroquinone	GSTM1 gene polymorphism affects the susceptibility to hydroquinone	15141365
C029899	imidazole	imidazole results in increased expression of GSTM1 mRNA	8951341
C545476	incobotulinumtoxinA	incobotulinumtoxinA results in increased expression of GSTM1 mRNA	29522793
C016517	indole-3-carbinol	indole-3-carbinol results in increased expression of GSTM1 protein	11309284
C016517	indole-3-carbinol	[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTM1 mRNA	22129741
C016517	indole-3-carbinol	[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GSTM1 mRNA	22129741
D007213	Indomethacin	Indomethacin results in increased expression of GSTM1 mRNA	18299717
D007306	Insecticides	GSTM1 gene polymorphism affects the susceptibility to Insecticides	12930676
D007460	Iodoacetamide	Iodoacetamide results in decreased activity of GSTM1 protein	1520269
D007501	Iron	Iron results in decreased expression of GSTM1 protein	11755321
D007501	Iron	Iron results in increased expression of GSTM1 mRNA	11755321
D007501	Iron	Iron results in increased expression of GSTM1 protein	11755321
D007505	Iron-Dextran Complex	[Iron-Dextran Complex co-treated with Tetrachlorodibenzodioxin] results in increased expression of GSTM1 protein	9443932
D007505	Iron-Dextran Complex	Iron-Dextran Complex results in increased expression of GSTM1 protein	9443932
C031050	isomethyleugenol	isomethyleugenol results in decreased activity of GSTM1 protein	8620581
D007538	Isoniazid	GSTM1 protein inhibits the reaction [CYP2E1 protein results in increased susceptibility to Isoniazid]	28762043
D007538	Isoniazid	GSTM1 protein results in decreased susceptibility to Isoniazid	28762043
C016527	isoquercitrin	[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA	20033131
C016527	isoquercitrin	isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA]	20045035
D015474	Isotretinoin	Isotretinoin results in decreased expression of GSTM1 mRNA	15982314
C098607	JP8 aviation fuel	JP8 aviation fuel results in increased expression of GSTM1 protein	10959803
C053401	kahweol	[cafestol co-treated with kahweol] results in increased expression of GSTM1 protein	11346484
C033997	kahweol palmitate	[cafestol co-treated with kahweol palmitate] results in increased expression of GSTM1 protein	11309284
D007654	Ketoconazole	Ketoconazole results in increased expression of GSTM1 protein	17966066
C011890	kojic acid	[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM1 mRNA	18544905
C011890	kojic acid	[Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM1 mRNA	18544905
D007854	Lead	[GSTM1 gene mutant form co-treated with GSTT1 gene mutant form] promotes the reaction [Lead results in increased expression of CRP protein]	23484121
D007854	Lead	[GSTM1 gene mutant form co-treated with GSTT1 gene mutant form] results in increased susceptibility to Lead	23484121
D007854	Lead	GSTM1 gene mutant form promotes the reaction [Lead results in increased expression of CRP protein]	23484121
D007854	Lead	GSTM1 gene mutant form results in increased susceptibility to Lead	23484121
C008261	lead acetate	lead acetate affects the localization of GSTM1 protein	9750042
C008261	lead acetate	lead acetate results in increased expression of GSTM1 mRNA	9750042
C008261	lead acetate	lead acetate results in increased expression of GSTM1 protein	7878682; 9750042;
C029891	lead chloride	lead chloride results in decreased expression of GSTM1 protein	30359721
D017705	Lignans	Lignans results in increased expression of GSTM1 mRNA	26678224
D000077222	Limonene	Limonene results in increased expression of GSTM1 protein	23159986
D008054	Lipid Peroxides	GSTM1 protein affects the metabolism of and results in decreased susceptibility to Lipid Peroxides	9576856
C482199	lipopolysaccharide, E coli O55-B5	[lipopolysaccharide, E coli O55-B5 co-treated with Benzo(a)pyrene] affects the expression of GSTM1 mRNA	28987381
D008070	Lipopolysaccharides	Lipopolysaccharides results in increased expression of GSTM1 mRNA	24001438
D008070	Lipopolysaccharides	Plant Extracts inhibits the reaction [Lipopolysaccharides results in increased expression of GSTM1 mRNA]	24001438
D008070	Lipopolysaccharides	Lipopolysaccharides inhibits the reaction [E804 bisindole results in decreased expression of GSTM1 mRNA]	23107598
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased expression of GSTM1 mRNA	27339419
D008094	Lithium	Lithium results in increased expression of GSTM1 mRNA	18082333
D008094	Lithium	Lithium results in increased expression of GSTM1 protein	18296634
D008095	Lithocholic Acid	Lithocholic Acid results in increased expression of GSTM1 mRNA	20977460
D008095	Lithocholic Acid	NFE2L2 protein promotes the reaction [Lithocholic Acid results in increased expression of GSTM1 mRNA]	20977460
D008095	Lithocholic Acid	Lithocholic Acid binds to and results in decreased activity of GSTM1 protein	3954743
D008528	Mefenamic Acid	GSTM1 protein results in increased glutathionylation of Mefenamic Acid analog	25372302
D008550	Melatonin	[Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of GSTM1 mRNA	20033131
D008558	Melphalan	GSTM1 protein results in decreased susceptibility to Melphalan	20067466
D015122	Mercaptopurine	GSTM1 gene polymorphism affects the susceptibility to Mercaptopurine	15713801
D008627	Mercuric Chloride	[Mercuric Chloride results in increased abundance of Mercury] which results in decreased expression of GSTM1 protein	30359721
D008627	Mercuric Chloride	Mercuric Chloride results in increased expression of GSTM1 protein	9434069
D008628	Mercury	GSTM1 gene polymorphism affects the abundance of Mercury	25728017
D008628	Mercury	GSTM1 gene polymorphism affects the susceptibility to Mercury	20194072
D008628	Mercury	[GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] affects the susceptibility to Mercury	24319713
D008628	Mercury	GSTM1 polymorphism affects the susceptibility to Mercury	17716707
D008628	Mercury	[GSTP1 gene polymorphism co-treated with GSTM1 gene polymorphism] affects the abundance of Mercury	19515364
D008628	Mercury	[Mercuric Chloride results in increased abundance of Mercury] which results in decreased expression of GSTM1 protein	30359721
D058955	Metalloids	GSTM1 gene polymorphism affects the susceptibility to Metalloids	24036326
D008670	Metals	GSTM1 gene polymorphism affects the susceptibility to Metals	14504370; 24036326;
D008694	Methamphetamine	GSTM1 gene polymorphism affects the susceptibility to Methamphetamine	15048646
D008694	Methamphetamine	GSTM1 protein results in decreased susceptibility to Methamphetamine	19254865
D008694	Methamphetamine	Methamphetamine results in increased expression of GSTM1 mRNA	29802913
D008715	Methionine	Methionine affects the expression of GSTM1 mRNA	11040448
D008727	Methotrexate	GSTM1 gene polymorphism affects the susceptibility to Methotrexate	15713801
D008727	Methotrexate	GSTM1 mRNA results in decreased susceptibility to Methotrexate	23675469
D008727	Methotrexate	Methotrexate affects the expression of GSTM1 mRNA	18502557
D008748	Methylcholanthrene	Methylcholanthrene results in increased expression of GSTM1 mRNA	11328961; 23273579;
D008750	Methyldopa	Methyldopa analog results in decreased activity of GSTM1 protein	8131222
C005223	methyleugenol	methyleugenol results in decreased activity of GSTM1 protein	8620581
C004925	methylmercuric chloride	methylmercuric chloride results in decreased expression of GSTM1 mRNA	12215206
C004925	methylmercuric chloride	methylmercuric chloride results in decreased activity of GSTM1 protein	1793546
D008767	Methylmercury Compounds	GSTM1 gene polymorphism affects the metabolism of Methylmercury Compounds	24696865
C063855	microcystin RR	GSTM1 protein results in increased glutathionylation of microcystin RR	23538035
D052998	Microcystins	Microcystins affects the expression of GSTM1 mRNA	19790251
C000627226	momfluorothrin	momfluorothrin results in increased expression of GSTM1 mRNA	28520973
C016599	mono-(2-ethylhexyl)phthalate	mono-(2-ethylhexyl)phthalate results in increased expression of GSTM1 protein	27384973
D016686	Monocrotaline	[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein	21224054
C020300	monomethylarsonic acid	monomethylarsonic acid results in increased expression of GSTM1 mRNA	16436460
C020300	monomethylarsonic acid	monomethylarsonic acid results in increased expression of GSTM1 protein	16436460
C517284	monomethyl phthalate	monomethyl phthalate results in increased expression of GSTM1 mRNA	26924002
C005939	muconic acid	[GSTM1 protein affects the metabolism of Benzene] which affects the abundance of muconic acid	10511268
D009151	Mustard Gas	Mustard Gas results in decreased expression of GSTM1 mRNA	18955075
C583365	N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of GSTM1 mRNA	29244179
C569465	N-acetyl-S-(2-carbamoylethyl)cysteine	[GSTM1 gene polymorphism affects the metabolism of Acrylamide] which affects the chemical synthesis of N-acetyl-S-(2-carbamoylethyl)cysteine	21402133
D037742	Nanotubes, Carbon	Nanotubes, Carbon analog results in decreased expression of GSTM1 mRNA	25554681; 25620056;
D037742	Nanotubes, Carbon	Nanotubes, Carbon results in decreased expression of GSTM1 mRNA	25554681; 25620056;
C031721	naphthalene	naphthalene results in increased expression of GSTM1 mRNA	20500019
C031721	naphthalene	naphthalene affects the expression of GSTM1 protein	10959795
C031721	naphthalene	naphthalene results in decreased expression of GSTM1 protein	19438287
C051752	nefazodone	nefazodone results in increased expression of GSTM1 mRNA	24136188
D019829	Nevirapine	GSTM1 protein results in increased glutathionylation of Nevirapine metabolite	27989146
D009532	Nickel	Nickel results in decreased expression of GSTM1 mRNA	24768652; 25583101;
C012655	nimesulide	nimesulide results in increased expression of GSTM1 mRNA	24136188
D009569	Nitric Oxide	Nitric Oxide deficiency results in increased expression of GSTM1 mRNA	15878706
D009585	Nitrogen Dioxide	GSTM1 gene polymorphism affects the susceptibility to Nitrogen Dioxide	22732554
C025589	ochratoxin A	ochratoxin A results in decreased expression of GSTM1 mRNA	23358140
C025589	ochratoxin A	ochratoxin A results in decreased expression of GSTM1 protein	17110534
C014138	octachlorostyrene	octachlorostyrene results in increased expression of GSTM1 mRNA	18036774
D019319	Okadaic Acid	Okadaic Acid results in increased expression of GSTM1 mRNA	28939011
C026209	oltipraz	NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM1 mRNA]	22496397
C026209	oltipraz	[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM1 mRNA	22496397
C026209	oltipraz	oltipraz results in increased expression of GSTM1 mRNA	18723825; 22496397;
C026209	oltipraz	oltipraz results in increased expression of GSTM1 mRNA	9203627
D010755	Organophosphates	GSTM1 gene polymorphism affects the susceptibility to Organophosphates	26318115
D010081	Oxazolone	Oxazolone results in decreased expression of GSTM1 mRNA	21404309
C011030	oxfendazole	[Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of GSTM1 mRNA	20033131
C011030	oxfendazole	[Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of GSTM1 mRNA	20033131
C011030	oxfendazole	[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of GSTM1 mRNA	20033131
C011030	oxfendazole	[oxfendazole co-treated with Diethylnitrosamine] results in increased expression of GSTM1 mRNA	18754104
C005290	oxybenzone	oxybenzone results in increased expression of GSTM1 mRNA	30316929
D010100	Oxygen	Oxygen deficiency results in decreased expression of GSTM1 mRNA	19695866
D010100	Oxygen	[NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of GSTM1 mRNA	30529165
D010126	Ozone	GSTM1 gene polymorphism affects the susceptibility to Ozone	22732554
D010126	Ozone	GSTM1 gene polymorphism promotes the reaction [NQO1 gene SNP results in increased susceptibility to Ozone]	17652311
D010126	Ozone	GSTM1 gene SNP affects the reaction [MS4A2 gene SNP affects the susceptibility to Ozone]	18269668
D010126	Ozone	GSTM1 gene SNP affects the reaction [TNF gene SNP affects the susceptibility to Ozone]	16456144
D010126	Ozone	GSTM1 gene SNP results in increased susceptibility to Ozone	16870661
D010126	Ozone	GSTM1 protein affects the susceptibility to Ozone	11371413
D010126	Ozone	Ozone results in decreased expression of GSTM1 mRNA	12763052
D017239	Paclitaxel	GSTM1 gene polymorphism affects the susceptibility to [Paclitaxel co-treated with Cisplatin]	12851839
D000073878	Palm Oil	Palm Oil affects the expression of GSTM1 mRNA	19680557
D010269	Paraquat	Paraquat results in increased expression of GSTM1 mRNA	16128001
D052638	Particulate Matter	GSTM1 gene polymorphism affects the susceptibility to Particulate Matter	22732554
D052638	Particulate Matter	GSTM1 mutant form promotes the reaction [Particulate Matter results in increased expression of CD40]	21169129
D052638	Particulate Matter	GSTM1 mutant form promotes the reaction [Particulate Matter results in increased expression of CD80]	21169129
D052638	Particulate Matter	GSTM1 mutant form promotes the reaction [Particulate Matter results in increased expression of CD86]	21169129
D052638	Particulate Matter	GSTM1 mutant form promotes the reaction [Particulate Matter results in increased expression of CXCL8 protein]	22867088
D052638	Particulate Matter	GSTM1 mutant form promotes the reaction [Particulate Matter results in increased expression of FCER2]	21169129
D052638	Particulate Matter	GSTM1 mutant form promotes the reaction [Particulate Matter results in increased expression of IL1B protein]	22867088
D052638	Particulate Matter	GSTM1 mutant form promotes the reaction [Particulate Matter results in increased phosphorylation of AKT1 protein]	22867088
D052638	Particulate Matter	GSTM1 mutant form promotes the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein]	22867088
D052638	Particulate Matter	GSTM1 mutant form promotes the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein]	22867088
D052638	Particulate Matter	GSTM1 results in decreased susceptibility to Particulate Matter	21169129
D052638	Particulate Matter	NFE2L2 gene mutant form inhibits the reaction [Particulate Matter results in increased expression of GSTM1 mRNA]	18614404
D052638	Particulate Matter	Particulate Matter results in decreased expression of GSTM1 mRNA	18307122
D052638	Particulate Matter	Particulate Matter results in decreased expression of GSTM1 protein	18307122
D052638	Particulate Matter	Particulate Matter results in increased expression of GSTM1 mRNA	18614404
D052638	Particulate Matter	Particulate Matter results in increased expression of GSTM1 mRNA	22352393
D010416	Pentachlorophenol	Pentachlorophenol results in increased expression of GSTM1 mRNA	23892564
C076994	perfluorooctane sulfonic acid	perfluorooctane sulfonic acid affects the expression of GSTM1 mRNA	19429403
C023036	perfluorooctanoic acid	perfluorooctanoic acid affects the expression of GSTM1 mRNA	18281256; 19429403;
C023036	perfluorooctanoic acid	[perfluorooctanoic acid co-treated with Dietary Fats, Unsaturated] results in increased expression of GSTM1 mRNA	23626681
C023036	perfluorooctanoic acid	perfluorooctanoic acid results in decreased expression of GSTM1 mRNA	18467677
C023036	perfluorooctanoic acid	PPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of GSTM1 mRNA]	18467677
D026023	Permethrin	Permethrin results in increased expression of GSTM1 mRNA	30629241
D010575	Pesticides	GSTM1 gene polymorphism affects the susceptibility to Pesticides	14504370; 15922524; 18550589; 23982010; 27185341; 27406225;
D010575	Pesticides	GSTM1 protein results in increased susceptibility to Pesticides	18550589
C031181	phenanthrene	GSTM1 gene polymorphism promotes the reaction [CYP1A1 gene polymorphism results in increased metabolism of phenanthrene]	17035385
C031181	phenanthrene	GSTM1 protein affects the metabolism of phenanthrene	22674470
C058305	phenethyl isothiocyanate	GSTM1 protein affects the metabolism of phenethyl isothiocyanate	7826396
D010634	Phenobarbital	Phenobarbital results in decreased expression of GSTM1 mRNA	19952500
D010634	Phenobarbital	Phenobarbital results in decreased expression of GSTM1 protein	7986210
D010634	Phenobarbital	Phenobarbital results in increased expression of GSTM1 mRNA	28541575
D010634	Phenobarbital	Phenobarbital results in increased expression of GSTM1 protein	28541575
D010634	Phenobarbital	Phenobarbital results in increased expression of GSTM1 mRNA	18723825; 20403969; 23091169; 26519955; 28541575;
D010634	Phenobarbital	[Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of GSTM1 protein	20935162
D010634	Phenobarbital	Phenobarbital results in increased expression of GSTM1 mRNA	11328961; 17381134; 19162173; 19695238; 23273579;
D010634	Phenobarbital	Phenobarbital results in increased expression of GSTM1 protein	8242872
C509597	phenylpropylene oxide	GSTM1 protein affects the metabolism of phenylpropylene oxide	17689871
D010672	Phenytoin	[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein	21224054
D010672	Phenytoin	Phenytoin results in increased expression of GSTM1 mRNA	17381134
D010695	Phlorhizin	Phlorhizin results in decreased expression of GSTM1 mRNA	22538082
D010847	Picolines	Picolines results in decreased expression of GSTM1 protein	7986210
C004479	pimagedine	pimagedine inhibits the reaction [Spermidine results in increased expression of GSTM1 mRNA]	12763045
D010882	Piperonyl Butoxide	Piperonyl Butoxide results in increased expression of GSTM1 mRNA	18544911
D010882	Piperonyl Butoxide	Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of GSTM1 mRNA]	18544911
C006253	pirinixic acid	pirinixic acid results in decreased expression of GSTM1 mRNA	18467677; 20813756;
C006253	pirinixic acid	PPARA protein promotes the reaction [pirinixic acid results in decreased expression of GSTM1 mRNA]	18467677
D010936	Plant Extracts	Plant Extracts inhibits the reaction [Lipopolysaccharides results in increased expression of GSTM1 mRNA]	24001438
D010936	Plant Extracts	Plant Extracts results in increased expression of GSTM1 protein	15570060
D017671	Platinum Compounds	GSTM1 affects the susceptibility to Platinum Compounds	21844884
D011084	Polycyclic Aromatic Hydrocarbons	GSTM1 gene polymorphism affects the secretion of Polycyclic Aromatic Hydrocarbons	21359562
D011084	Polycyclic Aromatic Hydrocarbons	GSTM1 gene polymorphism affects the susceptibility to Polycyclic Aromatic Hydrocarbons	15036119; 15061915; 15466980;
D011084	Polycyclic Aromatic Hydrocarbons	GSTM1 protein affects the metabolism of and results in decreased activity of Polycyclic Aromatic Hydrocarbons	15122594
D011084	Polycyclic Aromatic Hydrocarbons	GSTM1 protein polymorphism results in increased susceptibility to Polycyclic Aromatic Hydrocarbons	11740339
D011084	Polycyclic Aromatic Hydrocarbons	GSTM1 protein results in decreased activity of Polycyclic Aromatic Hydrocarbons	15122594
C095911	polycyclic aromatic hydrocarbons-DNA adduct	GSTM1 protein polymorphism results in increased abundance of polycyclic aromatic hydrocarbons-DNA adduct	11967624
D011192	Potassium Dichromate	Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSTM1 mRNA]	23470461
D011192	Potassium Dichromate	Potassium Dichromate results in decreased expression of GSTM1 mRNA	23470461
D011241	Prednisone	GSTM1 gene polymorphism affects the susceptibility to Prednisone	15713801
D011285	Pregnenolone Carbonitrile	NR1I2 protein affects the reaction [Pregnenolone Carbonitrile results in increased expression of GSTM1 mRNA]	22496397
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein binds to GSTM1 5' UTR]	20693526
D011285	Pregnenolone Carbonitrile	[Pregnenolone Carbonitrile results in increased activity of NR1I2 protein] which results in increased expression of GSTM1 mRNA	22496397
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of GSTM1 mRNA	18723825; 22496397; 27413110; 28903501;
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of GSTM1 mRNA	19162173
C045950	propiconazole	propiconazole results in increased expression of GSTM1 mRNA	21278054; 22334560;
C045950	propiconazole	propiconazole affects the expression of GSTM1 mRNA	17383973
C100008	prostaglandin A2	GSTM1 protein affects the metabolism of prostaglandin A2	9084911
D054328	Proton Pump Inhibitors	Proton Pump Inhibitors results in increased expression of GSTM1 mRNA	25626140
C513428	pyrachlostrobin	pyrachlostrobin results in increased expression of GSTM1 mRNA	27029645
D011718	Pyrazinamide	Pyrazinamide results in increased expression of GSTM1 mRNA	22431067
D011719	Pyrazines	Pyrazines results in decreased expression of GSTM1 protein	7986210
C031280	pyrazole	pyrazole results in increased expression of GSTM1 mRNA	17945193
C031280	pyrazole	pyrazole results in increased expression of GSTM1 protein	14610226
C030984	pyrene	[Docosahexaenoic Acids co-treated with pyrene] results in decreased expression of GSTM1 protein	25956473
C030984	pyrene	pyrene results in increased expression of GSTM1 mRNA	26160115
D011802	Quinidine	Quinidine results in decreased activity of GSTM1 protein	11807801
D011803	Quinine	Quinine results in decreased activity of GSTM1 protein	11807801
C502234	r-1,t-2,3,c-4-tetrahydroxy-1,2,3,4-tetrahydrophenanthrene	GSTM1 protein affects the chemical synthesis of r-1,t-2,3,c-4-tetrahydroxy-1,2,3,4-tetrahydrophenanthrene	22674470
D000077185	Resveratrol	Resveratrol results in increased expression of GSTM1 mRNA	19228061
C013672	riddelliine	riddelliine results in decreased expression of GSTM1 mRNA	18047727
D012293	Rifampin	[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein	21224054
D012294	Rifamycins	Rifamycins results in decreased expression of GSTM1 protein	7986210
D000077154	Rosiglitazone	Rosiglitazone affects the expression of GSTM1 mRNA	17245590
D012402	Rotenone	Rotenone affects the expression of GSTM1 mRNA	23186747
C015499	schizandrin B	schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of GSTM1 mRNA]	31150632
D012822	Silicon Dioxide	Silicon Dioxide analog results in decreased expression of GSTM1 mRNA	25895662
D012834	Silver	Silver results in increased expression of GSTM1 mRNA	27131904
D018030	Silver Compounds	Silver Compounds results in increased expression of GSTM1 mRNA	29703973
D012906	Smoke	GSTM1 affects the susceptibility to Smoke	19464563
D012906	Smoke	[GSTM1 polymorphism co-treated with Smoke] affects the abundance of S-phenyl-N-acetylcysteine	21300142
C017947	sodium arsenite	GSTM1 gene polymorphism affects the susceptibility to sodium arsenite	25395496
C017947	sodium arsenite	NFE2L1 protein alternative form inhibits the reaction [sodium arsenite results in increased expression of GSTM1 mRNA]	28549828
C017947	sodium arsenite	sodium arsenite results in increased expression of GSTM1 mRNA	28549828
C017947	sodium arsenite	sodium arsenite results in increased expression of GSTM1 protein	29459688
D012982	Sodium, Dietary	GSTM1 gene polymorphism affects the susceptibility to Sodium, Dietary	14696128
D012969	Sodium Fluoride	Sodium Fluoride results in decreased expression of GSTM1 mRNA	28089781
D012997	Solvents	GSTM1 gene polymorphism affects the susceptibility to Solvents	17449559
D012997	Solvents	GSTM1 polymorphism affects the susceptibility to Solvents	24914957
D012999	Soman	Soman results in decreased expression of GSTM1 mRNA	19281266
D053260	Soot	GSTM1 affects the susceptibility to Soot	21385671
D053260	Soot	GSTM1 gene SNP affects the susceptibility to Soot	19884647
D053260	Soot	Soot results in decreased expression of GSTM1 mRNA	22461453
D053260	Soot	Soot affects the expression of GSTM1 mRNA	23065132
D053260	Soot	Soot results in decreased expression of GSTM1 mRNA	21914721
D013095	Spermidine	pimagedine inhibits the reaction [Spermidine results in increased expression of GSTM1 mRNA]	12763045
D013095	Spermidine	Spermidine results in increased expression of GSTM1 mRNA	12763045
C053003	S-phenyl-N-acetylcysteine	GSTA1 gene polymorphism affects the reaction [GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine]	20100551
C053003	S-phenyl-N-acetylcysteine	GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine	20100551
C053003	S-phenyl-N-acetylcysteine	GSTM1 polymorphism affects the abundance of S-phenyl-N-acetylcysteine	17056211
C053003	S-phenyl-N-acetylcysteine	[GSTM1 polymorphism co-treated with Smoke] affects the abundance of S-phenyl-N-acetylcysteine	21300142
C053003	S-phenyl-N-acetylcysteine	GSTT1 gene polymorphism affects the reaction [GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine]	20100551
D013148	Spironolactone	Spironolactone results in increased expression of GSTM1 mRNA	18723825
D020058	Styrene	GSTM1 gene polymorphism affects the susceptibility to Styrene	12717779; 14751678; 14979085;
D020058	Styrene	GSTM1 gene polymorphism promotes the reaction [GSTT1 gene polymorphism results in increased susceptibility to Styrene]	12016165
D020058	Styrene	GSTM1 gene polymorphism results in increased susceptibility to Styrene	12016165
D020058	Styrene	GSTM1 protein affects the reaction [CYP2E1 protein affects the metabolism of Styrene]	12464798
C013690	styrene oxide	GSTM1 protein affects the metabolism of styrene oxide	11599931; 17689871;
C013690	styrene oxide	GSTM1 protein results in decreased susceptibility to styrene oxide	11424177; 14698568;
C013690	styrene oxide	GSTM1 protein affects the metabolism of styrene oxide	1638515
C013690	styrene oxide	GSTM1 protein affects the metabolism of [styrene oxide co-treated with Glutathione]	2604743
D013442	Sulfinpyrazone	Sulfinpyrazone inhibits the reaction [GSTM1 protein results in decreased susceptibility to Vincristine]	15044619
D013448	Sulfobromophthalein	Sulfobromophthalein inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]	7733673
D013448	Sulfobromophthalein	Sulfobromophthalein results in decreased activity of GSTM1 protein	7733673
C014202	sulfolithocholic acid	sulfolithocholic acid binds to and results in decreased activity of GSTM1 protein	3954743
C016766	sulforafan	GSTM1 gene polymorphism affects the susceptibility to sulforafan	15623468
C016766	sulforafan	GSTM1 protein affects the metabolism of sulforafan	7826396
C016766	sulforafan	sulforafan inhibits the reaction [alpha-methylepinine results in increased expression of GSTM1 mRNA]	21871945
C016766	sulforafan	sulforafan results in increased expression of GSTM1 protein	16905640
C016766	sulforafan	NFE2L2 protein promotes the reaction [sulforafan results in increased expression of GSTM1 mRNA]	20932822
C016766	sulforafan	[sulforafan co-treated with dibenzoylmethane] results in increased expression of GSTM1 mRNA	17942926
C016766	sulforafan	sulforafan inhibits the reaction [fenamidone results in increased expression of GSTM1 mRNA]	27029645
C016766	sulforafan	sulforafan results in increased expression of GSTM1 mRNA	17942926; 19071154; 19303893; 20932822; 24184564;
C016766	sulforafan	sulforafan results in increased expression of GSTM1 protein	11309284; 19303893;
C016766	sulforafan	sulforafan results in increased expression of GSTM1 protein	18823965
D013457	Sulfur Compounds	GSTM1 gene polymorphism affects the susceptibility to Sulfur Compounds	15033463
C074269	Sunphenon	[3,4,5,3',4'-pentachlorobiphenyl co-treated with Sunphenon] affects the expression of GSTM1 mRNA	24378064
D013481	Superoxides	GSTM1 protein results in decreased susceptibility to Superoxides	10661898
C557331	TAK-875	TAK-875 results in increased expression of GSTM1 mRNA	28206647
C013698	tallow	tallow affects the expression of GSTM1 mRNA	19680557
C061133	tamibarotene	tamibarotene results in increased expression of GSTM1 mRNA	15498508
D013629	Tamoxifen	[Carbon Tetrachloride co-treated with Tamoxifen] affects the expression of GSTM1 mRNA	29974145
C003377	taxifolin	taxifolin results in increased expression of GSTM1 mRNA	17541156
D013662	Tea	Tea inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased activity of GSTM1 protein]	12725062
D013739	Testosterone	[Testosterone co-treated with Calcitriol] results in increased expression of GSTM1 mRNA	21592394
D013739	Testosterone	Testosterone results in increased expression of GSTM1 mRNA	21592394
C004648	testosterone enanthate	testosterone enanthate affects the expression of GSTM1 mRNA	17440010
D013749	Tetrachlorodibenzodioxin	GSTM1 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]	7585625
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of GSTM1 mRNA	12377990
D013749	Tetrachlorodibenzodioxin	AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTM1 mRNA]	22496397
D013749	Tetrachlorodibenzodioxin	[Iron-Dextran Complex co-treated with Tetrachlorodibenzodioxin] results in increased expression of GSTM1 protein	9443932
D013749	Tetrachlorodibenzodioxin	NFE2L2 protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTM1 mRNA]	19474220
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of GSTM1 mRNA	20702594; 21570461;
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of GSTM1 mRNA	16214954
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of GSTM1 mRNA	28433925
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of GSTM1 mRNA	15034205; 17949056; 18172886; 18796159; 19474220; 22496397;
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of GSTM1 protein	9443932
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of GSTM1 mRNA	20959002
D013844	Thiazoles	Thiazoles results in increased expression of GSTM1 mRNA	8951341
D013844	Thiazoles	Thiazoles results in increased expression of GSTM1 protein	8951341
D013849	Thimerosal	GSTM1 affects the susceptibility to Thimerosal	11007341
D013853	Thioacetamide	[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of GSTM1 mRNA	23830814
D013853	Thioacetamide	[Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of GSTM1 mRNA	23830814; 28943392;
D013853	Thioacetamide	Dimethyl Sulfoxide inhibits the reaction [Thioacetamide results in decreased expression of GSTM1 protein]	12370186
D013853	Thioacetamide	Thioacetamide results in decreased expression of GSTM1 protein	12370186
D013853	Thioacetamide	Thioacetamide results in increased expression of GSTM1 mRNA	15497818
D008063	Thioctic Acid	[Dietary Fats co-treated with Thioctic Acid] results in increased expression of GSTM1 mRNA	18367378
D008063	Thioctic Acid	[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in increased expression of GSTM1 mRNA	23830814
C009495	titanium dioxide	titanium dioxide results in decreased expression of GSTM1 mRNA	23557971
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in decreased expression of GSTM1 mRNA	30291989
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased susceptibility to GSTM1 protein polymorphism	23643483
D014028	Tobacco Smoke Pollution	[APOE gene mutant form affects the susceptibility to Tobacco Smoke Pollution] which results in increased expression of GSTM1 mRNA	24096154
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of GSTM1 mRNA	30659203
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of GSTM1 protein	22609517; 27319396;
C082032	tocotrienol, alpha	GSTM1 gene polymorphism affects the susceptibility to [Ascorbic Acid co-treated with tocotrienol, alpha]	15668500
D014050	Toluene	GSTM1 gene polymorphism affects the susceptibility to Toluene	17292523
D014051	Toluene 2,4-Diisocyanate	GSTM1 protein polymorphism results in increased susceptibility to Toluene 2,4-Diisocyanate	11927838
D014051	Toluene 2,4-Diisocyanate	Toluene 2,4-Diisocyanate results in decreased expression of GSTM1 mRNA	21404309
D014212	Tretinoin	Tretinoin metabolite results in decreased expression of GSTM1 mRNA	15982314
D014212	Tretinoin	Tretinoin results in increased expression of GSTM1 mRNA	15498508
C032910	triadimefon	triadimefon affects the expression of GSTM1 mRNA	17383973
D014230	Triazoles	Triazoles results in increased expression of GSTM1 mRNA	8951341
C010360	triethyllead	triethyllead results in increased expression of GSTM1 mRNA	9020200
C015559	trimellitic anhydride	trimellitic anhydride results in decreased expression of GSTM1 mRNA	19042947
C052920	trimethylarsine oxide	trimethylarsine oxide results in increased expression of GSTM1 mRNA	16436460
C052920	trimethylarsine oxide	trimethylarsine oxide results in increased expression of GSTM1 protein	16436460
D014303	Trinitrotoluene	Trinitrotoluene affects the expression of GSTM1 mRNA	21346803
C012594	triphenyltin chloride	triphenyltin chloride inhibits the reaction [GSTM1 protein affects the metabolism of Dinitrochlorobenzene]	7733673
C012594	triphenyltin chloride	triphenyltin chloride results in decreased activity of GSTM1 protein	7733673
C016805	tris(1,3-dichloro-2-propyl)phosphate	tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of GSTM1 mRNA	26179874
D014315	Triterpenes	Triterpenes promotes the reaction [Piperonyl Butoxide results in increased expression of GSTM1 mRNA]	18544911
D000077288	Troglitazone	GSTM1 gene polymorphism affects the susceptibility to Troglitazone	12732844
C113580	U 0126	U 0126 affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of GSTM1 mRNA]	12710931
D014635	Valproic Acid	Valproic Acid affects the expression of GSTM1 mRNA	17292431
D014635	Valproic Acid	Valproic Acid results in increased expression of GSTM1 mRNA	17381134
D014638	Vanadates	Vanadates results in decreased expression of GSTM1 mRNA	22714537
D001335	Vehicle Emissions	GSTM1 mutant form promotes the reaction [Vehicle Emissions results in increased expression of CXCL8 protein]	22867088
D001335	Vehicle Emissions	GSTM1 mutant form promotes the reaction [Vehicle Emissions results in increased expression of IL1B protein]	22867088
D001335	Vehicle Emissions	GSTM1 mutant form promotes the reaction [Vehicle Emissions results in increased phosphorylation of AKT1 protein]	22867088
D001335	Vehicle Emissions	GSTM1 mutant form promotes the reaction [Vehicle Emissions results in increased phosphorylation of MAPK1 protein]	22867088
D001335	Vehicle Emissions	GSTM1 mutant form promotes the reaction [Vehicle Emissions results in increased phosphorylation of MAPK3 protein]	22867088
D001335	Vehicle Emissions	NFE2L2 gene mutant form inhibits the reaction [Vehicle Emissions results in increased expression of GSTM1 mRNA]	18614404
D001335	Vehicle Emissions	Vehicle Emissions results in decreased expression of GSTM1 mRNA	18307122
D001335	Vehicle Emissions	Vehicle Emissions results in decreased expression of GSTM1 protein	18307122
D001335	Vehicle Emissions	Vehicle Emissions results in decreased methylation of GSTM1 gene	25560391
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of GSTM1 mRNA	18614404
D001335	Vehicle Emissions	Vehicle Emissions results in decreased expression of GSTM1 mRNA	23905969
D001335	Vehicle Emissions	Vehicle Emissions results in increased expression of GSTM1 mRNA	22352393
C025643	vinclozolin	vinclozolin affects the expression of GSTM1 mRNA	23034163
C025643	vinclozolin	vinclozolin results in increased expression of GSTM1 mRNA	23034163
D014750	Vincristine	GSTM1 gene polymorphism affects the susceptibility to Vincristine	15713801
D014750	Vincristine	GSTM1 protein results in decreased susceptibility to Vincristine	15044619
D014750	Vincristine	Sulfinpyrazone inhibits the reaction [GSTM1 protein results in decreased susceptibility to Vincristine]	15044619
D014752	Vinyl Chloride	GSTM1 gene polymorphism affects the reaction [XRCC1 gene polymorphism affects the reaction [Vinyl Chloride affects the mutagenesis of TP53 gene]]	16097394
D014752	Vinyl Chloride	[GSTM1 gene polymorphism co-treated with GSTT1 gene polymorphism] results in increased susceptibility to Vinyl Chloride	16977343
C029297	vinylidene chloride	vinylidene chloride results in decreased expression of GSTM1 mRNA	26682919
D024483	Vitamin K 3	Vitamin K 3 results in increased expression of GSTM1 mRNA	14610226

Functional annotations

Keywords

Keyword ID	Keyword Term
KW-0002	3D-structure
KW-0025	Alternative splicing
KW-0963	Cytoplasm
KW-0903	Direct protein sequencing
KW-0597	Phosphoprotein
KW-0621	Polymorphism
KW-1185	Reference proteome
KW-0808	Transferase

Interpro

InterPro ID	InterPro Term
IPR010987	Glutathione-S-Trfase_C-like
IPR036282	Glutathione-S-Trfase_C_sf
IPR040079	Glutathione_S-Trfase
IPR004045	Glutathione_S-Trfase_N
IPR004046	GST_C
IPR003081	GST_mu
IPR036249	Thioredoxin-like_sf

PROSITE

PROSITE ID	PROSITE Term
PS50405	GST_CTER
PS50404	GST_NTER

Pfam

Pfam ID	Pfam Term
PF14497	GST_C_3
PF02798	GST_N

Gene: GSTM1

Basic information

Gene expression information

Gene expression in different tissues (GTEx V7)

Gene expression in different tissues (ENCODE)

Protein structural annotations

3D structure in PDB database

Protein disorder information

Orthologous information

There is no orthologous record for this gene !

Other genetic variants/mutations

Disease or phenotype associated information

Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO:Biological Process

GO:Cellular Component

Reactome Pathway

Drugs and compounds information

Functional annotations

Keywords

Interpro

PROSITE

Pfam

Protein-protein interaction