CleftGeneDB-Search

Gene: INHBB

Basic information

Tag	Content
Uniprot ID	P09529; Q53T31; Q8N1D3;
Entrez ID	3625
Genbank protein ID	AAH30029.1; AAA59451.1; AAA59170.1; EAW95243.1; AAY14801.1; AAA59169.1;
Genbank nucleotide ID	NM_002193.3
Ensembl protein ID	ENSP00000295228
Ensembl nucleotide ID	ENSG00000163083
Gene name	Inhibin beta B chain
Gene symbol	INHBB
Organism	Homo sapiens
NCBI taxa ID	9606
Cleft type
Developmental stage
Data sources	Homology search
Reference
Functional description	Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Sequence	MDGLPGRALG AACLLLLAAG WLGPEAWGSP TPPPTPAAPP PPPPPGSPGG SQDTCTSCGG 60 FRRPEELGRV DGDFLEAVKR HILSRLQMRG RPNITHAVPK AAMVTALRKL HAGKVREDGR 120 VEIPHLDGHA SPGADGQERV SEIISFAETD GLASSRVRLY FFISNEGNQN LFVVQASLWL 180 YLKLLPYVLE KGSRRKVRVK VYFQEQGHGD RWNMVEKRVD LKRSGWHTFP LTEAIQALFE 240 RGERRLNLDV QCDSCQELAV VPVFVDPGEE SHRPFVVVQA RLGDSRHRIR KRGLECDGRT 300 NLCCRQQFFI DFRLIGWNDW IIAPTGYYGN YCEGSCPAYL AGVPGSASSF HTAVVNQYRM 360 RGLNPGTVNS CCIPTKLSTM SMLYFDDEYN IVKRDVPNMI VEECGCA 407

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Gene expression information

Gene expression in different tissues (GTEx V7)

Gene expression in different tissues (ENCODE)

Protein structural annotations

3D structure in PDB database

There is no related protein structure for this gene.

Protein disorder information

Orthologous information

Relation	Gene symbol	Entrez ID	UniProt ID	Cleft type	Species	Evidence	Details
1:1 ortholog	INHBB	530430	A0A3Q1LMU4		Bos taurus	Prediction	More>>
1:1 ortholog	INHBB	100861250	A0A452FXK8		Capra hircus	Prediction	More>>
1:1 ortholog	INHBB	3625	P09529		Homo sapiens	Prediction	More>>
1:1 ortholog	Inhbb	16324	Q04999	CPO	Mus musculus	Publication	More>>
1:1 ortholog	INHBB	470524	A0A2I3TNV9		Pan troglodytes	Prediction	More>>
1:1 ortholog	INHBB		A0A287BPF5		Sus scrofa	Prediction	More>>
1:1 ortholog	INHBB		G1SN71		Oryctolagus cuniculus	Prediction	More>>
1:1 ortholog	Inhbb		A0A0G2K0C6		Rattus norvegicus	Prediction	More>>
1:1 ortholog	LOC100332902	100332902	A0A0G2KD75		Danio rerio	Prediction	More>>

Other genetic variants/mutations

ID	Variant	Type	Disease	Chromosome\Coordinate	Evidence
rs960624347	p.Gly3Arg	missense variant	-	NC_000002.12:g.120346195G>A	TOPMed,gnomAD
rs960624347	p.Gly3Trp	missense variant	-	NC_000002.12:g.120346195G>T	TOPMed,gnomAD
rs960624347	p.Gly3Arg	missense variant	-	NC_000002.12:g.120346195G>C	TOPMed,gnomAD
rs1450415604	p.Gly6Ala	missense variant	-	NC_000002.12:g.120346205G>C	TOPMed
rs1198729189	p.Gly6Arg	missense variant	-	NC_000002.12:g.120346204G>C	TOPMed
rs1181401457	p.Arg7Pro	missense variant	-	NC_000002.12:g.120346208G>C	TOPMed,gnomAD
rs1292041125	p.Arg7Trp	missense variant	-	NC_000002.12:g.120346207C>T	TOPMed
rs1181401457	p.Arg7Leu	missense variant	-	NC_000002.12:g.120346208G>T	TOPMed,gnomAD
rs1409949193	p.Ala8Thr	missense variant	-	NC_000002.12:g.120346210G>A	TOPMed,gnomAD
rs1272734266	p.Ala11Thr	missense variant	-	NC_000002.12:g.120346219G>A	TOPMed
rs1473807788	p.Ala12Ser	missense variant	-	NC_000002.12:g.120346222G>T	TOPMed,gnomAD
rs1473807788	p.Ala12Pro	missense variant	-	NC_000002.12:g.120346222G>C	TOPMed,gnomAD
rs1473807788	p.Ala12Thr	missense variant	-	NC_000002.12:g.120346222G>A	TOPMed,gnomAD
rs1434153838	p.Ala12Val	missense variant	-	NC_000002.12:g.120346223C>T	TOPMed
rs968275315	p.Ala19Asp	missense variant	-	NC_000002.12:g.120346244C>A	TOPMed
rs1303161649	p.Ala19Thr	missense variant	-	NC_000002.12:g.120346243G>A	TOPMed
rs1368231013	p.Trp21Cys	missense variant	-	NC_000002.12:g.120346251G>T	TOPMed
rs1429247332	p.Leu22Arg	missense variant	-	NC_000002.12:g.120346253T>G	gnomAD
rs1410212471	p.Gly23Arg	missense variant	-	NC_000002.12:g.120346255G>A	TOPMed
rs1468674990	p.Pro24Ser	missense variant	-	NC_000002.12:g.120346258C>T	TOPMed,gnomAD
rs1305058762	p.Glu25Ala	missense variant	-	NC_000002.12:g.120346262A>C	gnomAD
rs1271674533	p.Gly28Ala	missense variant	-	NC_000002.12:g.120346271G>C	TOPMed
rs1275457190	p.Pro34Leu	missense variant	-	NC_000002.12:g.120346289C>T	gnomAD
rs1200849451	p.Thr35Pro	missense variant	-	NC_000002.12:g.120346291A>C	TOPMed
rs1403758021	p.Ala37Val	missense variant	-	NC_000002.12:g.120346298C>T	gnomAD
rs1308329060	p.Pro40Ser	missense variant	-	NC_000002.12:g.120346306C>T	TOPMed
rs923684531	p.Pro42Ser	missense variant	-	NC_000002.12:g.120346312C>T	TOPMed,gnomAD
rs923684531	p.Pro42Ala	missense variant	-	NC_000002.12:g.120346312C>G	TOPMed,gnomAD
rs776937883	p.Pro44Leu	missense variant	-	NC_000002.12:g.120346319C>T	ExAC,gnomAD
rs1205688766	p.Pro45Leu	missense variant	-	NC_000002.12:g.120346322C>T	gnomAD
rs1250803329	p.Gly46Arg	missense variant	-	NC_000002.12:g.120346324G>A	gnomAD
rs11900747	p.Ser47Ala	missense variant	-	NC_000002.12:g.120346327T>G	1000Genomes,ExAC,TOPMed,gnomAD
rs922912209	p.Pro48Gln	missense variant	-	NC_000002.12:g.120346331C>A	TOPMed,gnomAD
rs922912209	p.Pro48Leu	missense variant	-	NC_000002.12:g.120346331C>T	TOPMed,gnomAD
rs922912209	p.Pro48Arg	missense variant	-	NC_000002.12:g.120346331C>G	TOPMed,gnomAD
rs1477431621	p.Gly50Ser	missense variant	-	NC_000002.12:g.120346336G>A	gnomAD
rs1172288935	p.Ser51Trp	missense variant	-	NC_000002.12:g.120346340C>G	gnomAD
rs1392629369	p.Gln52Pro	missense variant	-	NC_000002.12:g.120346343A>C	gnomAD
rs765759011	p.Asp53Asn	missense variant	-	NC_000002.12:g.120346345G>A	ExAC,TOPMed,gnomAD
rs1307740331	p.Thr54Ser	missense variant	-	NC_000002.12:g.120346349C>G	gnomAD
rs1394800610	p.Gly59Ser	missense variant	-	NC_000002.12:g.120346363G>A	gnomAD
rs1324496256	p.Gly60Ser	missense variant	-	NC_000002.12:g.120346366G>A	TOPMed,gnomAD
rs754649687	p.Arg62Gly	missense variant	-	NC_000002.12:g.120346372C>G	ExAC,TOPMed,gnomAD
rs754649687	p.Arg62Trp	missense variant	-	NC_000002.12:g.120346372C>T	ExAC,TOPMed,gnomAD
rs1301150662	p.Arg63Trp	missense variant	-	NC_000002.12:g.120346375C>T	gnomAD
rs781205948	p.Glu65Gln	missense variant	-	NC_000002.12:g.120346381G>C	ExAC,TOPMed,gnomAD
rs757403274	p.Gly68Cys	missense variant	-	NC_000002.12:g.120346390G>T	ExAC,TOPMed,gnomAD
rs757403274	p.Gly68Arg	missense variant	-	NC_000002.12:g.120346390G>C	ExAC,TOPMed,gnomAD
rs1450521842	p.Arg69Pro	missense variant	-	NC_000002.12:g.120346394G>C	gnomAD
rs1391489233	p.Val70Glu	missense variant	-	NC_000002.12:g.120346397T>A	gnomAD
rs778928618	p.Asp71Val	missense variant	-	NC_000002.12:g.120346400A>T	ExAC,gnomAD
rs1249970261	p.Gly72Cys	missense variant	-	NC_000002.12:g.120346402G>T	TOPMed,gnomAD
rs1249970261	p.Gly72Arg	missense variant	-	NC_000002.12:g.120346402G>C	TOPMed,gnomAD
rs1371662893	p.Asp73Asn	missense variant	-	NC_000002.12:g.120346405G>A	gnomAD
rs1327012748	p.Asp73Val	missense variant	-	NC_000002.12:g.120346406A>T	TOPMed
rs1390366565	p.Arg80Gln	missense variant	-	NC_000002.12:g.120346427G>A	TOPMed,gnomAD
rs1164029745	p.Arg80Trp	missense variant	-	NC_000002.12:g.120346426C>T	TOPMed,gnomAD
rs1390366565	p.Arg80Leu	missense variant	-	NC_000002.12:g.120346427G>T	TOPMed,gnomAD
rs1164029745	p.Arg80Gly	missense variant	-	NC_000002.12:g.120346426C>G	TOPMed,gnomAD
rs1322566739	p.Ile82Met	missense variant	-	NC_000002.12:g.120346434C>G	TOPMed,gnomAD
rs1045851878	p.Arg85His	missense variant	-	NC_000002.12:g.120346442G>A	gnomAD
rs1045851878	p.Arg85Leu	missense variant	-	NC_000002.12:g.120346442G>T	gnomAD
rs747402186	p.Gln87Arg	missense variant	-	NC_000002.12:g.120346448A>G	ExAC,gnomAD
rs768864104	p.Met88Ile	missense variant	-	NC_000002.12:g.120346452G>T	ExAC,gnomAD
rs777218845	p.Gly90Asp	missense variant	-	NC_000002.12:g.120346457G>A	ExAC,gnomAD
rs1337832826	p.Gly90Ser	missense variant	-	NC_000002.12:g.120346456G>A	TOPMed
rs1268651265	p.Asn93Ser	missense variant	-	NC_000002.12:g.120346466A>G	gnomAD
rs1431762618	p.Ile94Val	missense variant	-	NC_000002.12:g.120346468A>G	gnomAD
rs1035714724	p.His96Arg	missense variant	-	NC_000002.12:g.120346475A>G	TOPMed,gnomAD
rs762205967	p.His96Tyr	missense variant	-	NC_000002.12:g.120346474C>T	ExAC,TOPMed,gnomAD
rs562575760	p.Ala97Pro	missense variant	-	NC_000002.12:g.120346477G>C	1000Genomes
rs770515821	p.Lys100Met	missense variant	-	NC_000002.12:g.120346487A>T	ExAC,TOPMed,gnomAD
rs770515821	p.Lys100Thr	missense variant	-	NC_000002.12:g.120346487A>C	ExAC,TOPMed,gnomAD
rs1463427901	p.Met103Ile	missense variant	-	NC_000002.12:g.120346497G>C	TOPMed
rs529875491	p.Thr105Met	missense variant	-	NC_000002.12:g.120346502C>T	1000Genomes,TOPMed,gnomAD
rs1288201915	p.Arg108His	missense variant	-	NC_000002.12:g.120346511G>A	gnomAD
rs998841719	p.Ala112Glu	missense variant	-	NC_000002.12:g.120346523C>A	gnomAD
COSM4084536	p.Ala112Thr	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120346522G>A	NCI-TCGA Cosmic
rs763771792	p.Gly113Asp	missense variant	-	NC_000002.12:g.120346526G>A	ExAC,gnomAD
rs1214530105	p.Arg116Cys	missense variant	-	NC_000002.12:g.120346534C>T	gnomAD
rs757133834	p.Glu117Asp	missense variant	-	NC_000002.12:g.120346539G>C	ExAC,TOPMed,gnomAD
rs893115187	p.Arg120Gly	missense variant	-	NC_000002.12:g.120346546C>G	TOPMed,gnomAD
rs1291124907	p.Val121Met	missense variant	-	NC_000002.12:g.120346549G>A	TOPMed
rs923742193	p.His125Tyr	missense variant	-	NC_000002.12:g.120346561C>T	TOPMed,gnomAD
rs923742193	p.His125Asp	missense variant	-	NC_000002.12:g.120346561C>G	TOPMed,gnomAD
rs780288626	p.Leu126Phe	missense variant	-	NC_000002.12:g.120346564C>T	ExAC,gnomAD
rs747151266	p.Asp127Gly	missense variant	-	NC_000002.12:g.120346568A>G	ExAC,gnomAD
rs769114695	p.Asp127Glu	missense variant	-	NC_000002.12:g.120346569C>G	ExAC,gnomAD
rs748697458	p.Gly128Ala	missense variant	-	NC_000002.12:g.120346571G>C	ExAC,TOPMed,gnomAD
rs1386089217	p.Ala130Gly	missense variant	-	NC_000002.12:g.120346577C>G	TOPMed
rs201489869	p.Pro132Arg	missense variant	-	NC_000002.12:g.120346583C>G	1000Genomes,ExAC,TOPMed,gnomAD
rs1374594037	p.Gly133Val	missense variant	-	NC_000002.12:g.120346586G>T	gnomAD
rs1350803575	p.Gly136Ser	missense variant	-	NC_000002.12:g.120346594G>A	gnomAD
rs1263629524	p.Gln137His	missense variant	-	NC_000002.12:g.120346599G>C	TOPMed
rs931631684	p.Gln137Arg	missense variant	-	NC_000002.12:g.120346598A>G	TOPMed
rs1222861466	p.Glu138Val	missense variant	-	NC_000002.12:g.120346601A>T	gnomAD
rs986438315	p.Arg139Leu	missense variant	-	NC_000002.12:g.120346604G>T	TOPMed
COSM4084538	p.Ser141Pro	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120346609T>C	NCI-TCGA Cosmic
rs1252992323	p.Glu148Asp	missense variant	-	NC_000002.12:g.120346632G>C	TOPMed,gnomAD
rs1263108599	p.Thr149Ala	missense variant	-	NC_000002.12:g.120346633A>G	TOPMed
rs775328165	p.Thr149Ile	missense variant	-	NC_000002.12:g.120346634C>T	ExAC,gnomAD
rs1292293436	p.Gly151Asp	missense variant	-	NC_000002.12:g.120349102G>A	gnomAD
rs767641003	p.Leu152Phe	missense variant	-	NC_000002.12:g.120349104C>T	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Ala153Val	missense variant	-	NC_000002.12:g.120349108C>T	NCI-TCGA
rs756593615	p.Ala153Ser	missense variant	-	NC_000002.12:g.120349107G>T	ExAC,TOPMed,gnomAD
rs756593615	p.Ala153Thr	missense variant	-	NC_000002.12:g.120349107G>A	ExAC,TOPMed,gnomAD
rs1202336188	p.Ser154Ala	missense variant	-	NC_000002.12:g.120349110T>G	TOPMed
rs779417932	p.Arg156Gln	missense variant	-	NC_000002.12:g.120349117G>A	NCI-TCGA,NCI-TCGA Cosmic
rs757821876	p.Arg156Trp	missense variant	-	NC_000002.12:g.120349116C>T	ExAC,TOPMed,gnomAD
rs757821876	p.Arg156Gly	missense variant	-	NC_000002.12:g.120349116C>G	ExAC,TOPMed,gnomAD
rs779417932	p.Arg156Gln	missense variant	-	NC_000002.12:g.120349117G>A	ExAC,TOPMed,gnomAD
rs1295034640	p.Val157Gly	missense variant	-	NC_000002.12:g.120349120T>G	gnomAD
rs746505306	p.Arg158Cys	missense variant	-	NC_000002.12:g.120349122C>T	ExAC,gnomAD
rs768170550	p.Arg158His	missense variant	-	NC_000002.12:g.120349123G>A	ExAC,TOPMed,gnomAD
rs768170550	p.Arg158His	missense variant	-	NC_000002.12:g.120349123G>A	NCI-TCGA Cosmic
rs768170550	p.Arg158Leu	missense variant	-	NC_000002.12:g.120349123G>T	ExAC,TOPMed,gnomAD
rs746505306	p.Arg158Cys	missense variant	-	NC_000002.12:g.120349122C>T	NCI-TCGA,NCI-TCGA Cosmic
rs1434306336	p.Phe161Tyr	missense variant	-	NC_000002.12:g.120349132T>A	TOPMed,gnomAD
rs527898067	p.Phe162Ser	missense variant	-	NC_000002.12:g.120349135T>C	1000Genomes,ExAC,gnomAD
rs1339414880	p.Ile163Val	missense variant	-	NC_000002.12:g.120349137A>G	TOPMed
rs762936786	p.Asn165Ser	missense variant	-	NC_000002.12:g.120349144A>G	ExAC,TOPMed,gnomAD
rs774282504	p.Glu166Lys	missense variant	-	NC_000002.12:g.120349146G>A	ExAC,gnomAD
rs767587591	p.Gly167Asp	missense variant	-	NC_000002.12:g.120349150G>A	ExAC,TOPMed,gnomAD
rs759567914	p.Gly167Ser	missense variant	-	NC_000002.12:g.120349149G>A	ExAC,gnomAD
rs756397739	p.Asn170Asp	missense variant	-	NC_000002.12:g.120349158A>G	ExAC,gnomAD
rs967062614	p.Leu171Pro	missense variant	-	NC_000002.12:g.120349162T>C	TOPMed
rs764607634	p.Phe172Leu	missense variant	-	NC_000002.12:g.120349166T>A	ExAC,gnomAD
rs1189700671	p.Val173Ala	missense variant	-	NC_000002.12:g.120349168T>C	TOPMed
rs538498324	p.Val174Ile	missense variant	-	NC_000002.12:g.120349170G>A	1000Genomes,TOPMed
rs754265018	p.Trp179Ser	missense variant	-	NC_000002.12:g.120349186G>C	ExAC,gnomAD
rs757627693	p.Leu184Phe	missense variant	-	NC_000002.12:g.120349200C>T	ExAC,gnomAD
rs779319802	p.Leu185Arg	missense variant	-	NC_000002.12:g.120349204T>G	ExAC,gnomAD
rs750891174	p.Val188Ile	missense variant	-	NC_000002.12:g.120349212G>A	ExAC,gnomAD
COSM1005983	p.Gly192AlaPheSerTerUnkUnk	frameshift	Variant assessed as Somatic; HIGH impact.	NC_000002.12:g.120349223G>-	NCI-TCGA Cosmic
NCI-TCGA novel	p.Ser193Asn	missense variant	-	NC_000002.12:g.120349228G>A	NCI-TCGA
rs554007199	p.Arg194Trp	missense variant	-	NC_000002.12:g.120349230C>T	ExAC,gnomAD
rs769423198	p.Arg194Gln	missense variant	-	NC_000002.12:g.120349231G>A	ExAC,TOPMed,gnomAD
rs769423198	p.Arg194Gln	missense variant	-	NC_000002.12:g.120349231G>A	NCI-TCGA
rs554007199	p.Arg194Trp	missense variant	-	NC_000002.12:g.120349230C>T	NCI-TCGA,NCI-TCGA Cosmic
rs777351329	p.Arg195Trp	missense variant	-	NC_000002.12:g.120349233C>T	NCI-TCGA
rs749091093	p.Arg195Gln	missense variant	-	NC_000002.12:g.120349234G>A	ExAC,TOPMed,gnomAD
rs777351329	p.Arg195Trp	missense variant	-	NC_000002.12:g.120349233C>T	ExAC,TOPMed,gnomAD
rs1209103585	p.Lys196Met	missense variant	-	NC_000002.12:g.120349237A>T	TOPMed
rs770722399	p.Arg198Gly	missense variant	-	NC_000002.12:g.120349242C>G	ExAC,TOPMed,gnomAD
rs201609499	p.Arg198Gln	missense variant	-	NC_000002.12:g.120349243G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs770722399	p.Arg198Trp	missense variant	-	NC_000002.12:g.120349242C>T	ExAC,TOPMed,gnomAD
rs770722399	p.Arg198Trp	missense variant	-	NC_000002.12:g.120349242C>T	NCI-TCGA
rs759483459	p.Lys200Glu	missense variant	-	NC_000002.12:g.120349248A>G	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Val201Met	missense variant	-	NC_000002.12:g.120349251G>A	NCI-TCGA
rs1229259197	p.Val201Leu	missense variant	-	NC_000002.12:g.120349251G>C	TOPMed,gnomAD
rs144330762	p.Tyr202Cys	missense variant	-	NC_000002.12:g.120349255A>G	ESP,ExAC,TOPMed,gnomAD
rs975677798	p.Gln206Pro	missense variant	-	NC_000002.12:g.120349267A>C	TOPMed
rs4328642	p.His208Gln	missense variant	-	NC_000002.12:g.120349274C>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1207428819	p.His208Arg	missense variant	-	NC_000002.12:g.120349273A>G	gnomAD
rs142763860	p.Gly209Ser	missense variant	-	NC_000002.12:g.120349275G>A	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs1209979245	p.Asp210Asn	missense variant	-	NC_000002.12:g.120349278G>A	TOPMed,gnomAD
rs1255146313	p.Trp212Gly	missense variant	-	NC_000002.12:g.120349284T>G	gnomAD
rs370251196	p.Asn213Lys	missense variant	-	NC_000002.12:g.120349289C>G	ESP,ExAC,TOPMed,gnomAD
rs750934647	p.Met214Val	missense variant	-	NC_000002.12:g.120349290A>G	ExAC,gnomAD
COSM3565878	p.Met214Ile	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120349292G>A	NCI-TCGA Cosmic
rs1174813485	p.Arg218Ser	missense variant	-	NC_000002.12:g.120349304G>C	gnomAD
rs1047221496	p.Arg218Lys	missense variant	-	NC_000002.12:g.120349303G>A	TOPMed
rs1434647363	p.Leu221Arg	missense variant	-	NC_000002.12:g.120349312T>G	gnomAD
rs758941360	p.Lys222Arg	missense variant	-	NC_000002.12:g.120349315A>G	ExAC,gnomAD
rs755558554	p.Arg223His	missense variant	-	NC_000002.12:g.120349318G>A	ExAC,gnomAD
rs780625208	p.Arg223Cys	missense variant	-	NC_000002.12:g.120349317C>T	ExAC,gnomAD
rs755558554	p.Arg223Leu	missense variant	-	NC_000002.12:g.120349318G>T	ExAC,gnomAD
rs780625208	p.Arg223Ser	missense variant	-	NC_000002.12:g.120349317C>A	ExAC,gnomAD
rs780625208	p.Arg223Cys	missense variant	-	NC_000002.12:g.120349317C>T	NCI-TCGA,NCI-TCGA Cosmic
rs965669603	p.Ser224Gly	missense variant	-	NC_000002.12:g.120349320A>G	TOPMed
rs1269321605	p.Gly225Ser	missense variant	-	NC_000002.12:g.120349323G>A	TOPMed
rs748893887	p.His227Arg	missense variant	-	NC_000002.12:g.120349330A>G	ExAC,gnomAD
COSM3565880	p.Thr228Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120349332A>T	NCI-TCGA Cosmic
NCI-TCGA novel	p.Pro230Ser	missense variant	-	NC_000002.12:g.120349338C>T	NCI-TCGA
rs770683310	p.Thr232Arg	missense variant	-	NC_000002.12:g.120349345C>G	ExAC,TOPMed,gnomAD
rs770683310	p.Thr232Met	missense variant	-	NC_000002.12:g.120349345C>T	ExAC,TOPMed,gnomAD
rs770683310	p.Thr232Met	missense variant	-	NC_000002.12:g.120349345C>T	NCI-TCGA
rs1348423852	p.Ala234Val	missense variant	-	NC_000002.12:g.120349351C>T	gnomAD
rs760867489	p.Gln236Arg	missense variant	-	NC_000002.12:g.120349357A>G	ExAC,gnomAD
rs768807268	p.Leu238Ser	missense variant	-	NC_000002.12:g.120349363T>C	ExAC,gnomAD
COSM716025	p.Leu238Val	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120349362T>G	NCI-TCGA Cosmic
rs1249448875	p.Phe239Ser	missense variant	-	NC_000002.12:g.120349366T>C	gnomAD
rs202216864	p.Glu240Asp	missense variant	-	NC_000002.12:g.120349370G>T	1000Genomes,ESP,ExAC,TOPMed,gnomAD
rs374594988	p.Arg241Gln	missense variant	-	NC_000002.12:g.120349372G>A	ExAC,TOPMed,gnomAD
rs762062674	p.Arg241Trp	missense variant	-	NC_000002.12:g.120349371C>T	ExAC,gnomAD
rs763171160	p.Glu243Asp	missense variant	-	NC_000002.12:g.120349379G>C	ExAC,gnomAD
rs147613754	p.Arg244Gln	missense variant	-	NC_000002.12:g.120349381G>A	ESP,gnomAD
rs1302307316	p.Arg244Trp	missense variant	-	NC_000002.12:g.120349380C>T	gnomAD
rs147613754	p.Arg244Gln	missense variant	-	NC_000002.12:g.120349381G>A	NCI-TCGA
NCI-TCGA novel	p.Arg245Ter	stop gained	-	NC_000002.12:g.120349383C>T	NCI-TCGA
rs766879328	p.Arg245Gln	missense variant	-	NC_000002.12:g.120349384G>A	ExAC,gnomAD
rs755646306	p.Asn247Asp	missense variant	-	NC_000002.12:g.120349389A>G	ExAC,gnomAD
COSM4084540	p.Asn247Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120349390A>G	NCI-TCGA Cosmic
rs143435725	p.Asp249Glu	missense variant	-	NC_000002.12:g.120349397C>A	ESP,ExAC,TOPMed,gnomAD
rs745676362	p.Val250Leu	missense variant	-	NC_000002.12:g.120349398G>T	ExAC,TOPMed,gnomAD
rs745676362	p.Val250Met	missense variant	-	NC_000002.12:g.120349398G>A	ExAC,TOPMed,gnomAD
rs767436546	p.Gln251Lys	missense variant	-	NC_000002.12:g.120349401C>A	ExAC,TOPMed,gnomAD
rs1301215368	p.Gln251His	missense variant	-	NC_000002.12:g.120349403G>C	gnomAD
rs746918678	p.Asp253Gly	missense variant	-	NC_000002.12:g.120349408A>G	ExAC,gnomAD
rs539269278	p.Ser254Asn	missense variant	-	NC_000002.12:g.120349411G>A	1000Genomes,ExAC,gnomAD
rs148176831	p.Glu257Lys	missense variant	-	NC_000002.12:g.120349419G>A	ESP,ExAC,TOPMed,gnomAD
rs148176831	p.Glu257Lys	missense variant	-	NC_000002.12:g.120349419G>A	NCI-TCGA
rs1194122682	p.Leu258Arg	missense variant	-	NC_000002.12:g.120349423T>G	TOPMed
rs770068466	p.Val260Met	missense variant	-	NC_000002.12:g.120349428G>A	ExAC,TOPMed,gnomAD
rs770068466	p.Val260Met	missense variant	-	NC_000002.12:g.120349428G>A	NCI-TCGA,NCI-TCGA Cosmic
rs142105758	p.Val261Leu	missense variant	-	NC_000002.12:g.120349431G>T	ESP,ExAC,TOPMed,gnomAD
rs1192284361	p.Pro262Ser	missense variant	-	NC_000002.12:g.120349434C>T	gnomAD
rs1316704448	p.Pro262Leu	missense variant	-	NC_000002.12:g.120349435C>T	TOPMed,gnomAD
rs1192284361	p.Pro262Ser	missense variant	-	NC_000002.12:g.120349434C>T	NCI-TCGA
NCI-TCGA novel	p.Val263Leu	missense variant	-	NC_000002.12:g.120349437G>T	NCI-TCGA
rs774890593	p.Phe264Leu	missense variant	-	NC_000002.12:g.120349442C>G	ExAC,TOPMed,gnomAD
rs1343231594	p.Phe264Ser	missense variant	-	NC_000002.12:g.120349441T>C	TOPMed
rs760009603	p.Val265Gly	missense variant	-	NC_000002.12:g.120349444T>G	ExAC,TOPMed,gnomAD
rs760009603	p.Val265Ala	missense variant	-	NC_000002.12:g.120349444T>C	ExAC,TOPMed,gnomAD
rs753397591	p.Pro267Thr	missense variant	-	NC_000002.12:g.120349449C>A	ExAC
rs1444408843	p.Gly268Ser	missense variant	-	NC_000002.12:g.120349452G>A	TOPMed
rs752997062	p.Gly268Asp	missense variant	-	NC_000002.12:g.120349453G>A	ExAC,TOPMed,gnomAD
rs1459992323	p.Glu269Gln	missense variant	-	NC_000002.12:g.120349455G>C	gnomAD
rs904089802	p.Glu270Lys	missense variant	-	NC_000002.12:g.120349458G>A	NCI-TCGA Cosmic
rs904089802	p.Glu270Lys	missense variant	-	NC_000002.12:g.120349458G>A	gnomAD
rs1001095566	p.Ser271Leu	missense variant	-	NC_000002.12:g.120349462C>T	TOPMed
rs1001095566	p.Ser271Leu	missense variant	-	NC_000002.12:g.120349462C>T	NCI-TCGA Cosmic
rs747008552	p.His272Gln	missense variant	-	NC_000002.12:g.120349466C>G	ExAC,gnomAD
rs200288747	p.His272Tyr	missense variant	-	NC_000002.12:g.120349464C>T	1000Genomes,ExAC,gnomAD
rs781217919	p.Arg273Gln	missense variant	-	NC_000002.12:g.120349468G>A	ExAC,gnomAD
rs781217919	p.Arg273Gln	missense variant	-	NC_000002.12:g.120349468G>A	NCI-TCGA
rs754953119	p.Arg273Trp	missense variant	-	NC_000002.12:g.120349467C>T	ExAC,TOPMed,gnomAD
rs569598198	p.Val276Met	missense variant	-	NC_000002.12:g.120349476G>A	ExAC,TOPMed,gnomAD
rs773509193	p.Val278Met	missense variant	-	NC_000002.12:g.120349482G>A	ExAC,gnomAD
rs542203870	p.Gln279His	missense variant	-	NC_000002.12:g.120349487G>C	1000Genomes,ExAC,TOPMed,gnomAD
rs144228850	p.Arg281Trp	missense variant	-	NC_000002.12:g.120349491C>T	NCI-TCGA,NCI-TCGA Cosmic
rs144228850	p.Arg281Gly	missense variant	-	NC_000002.12:g.120349491C>G	ESP,ExAC,TOPMed,gnomAD
rs560571608	p.Arg281Gln	missense variant	-	NC_000002.12:g.120349492G>A	NCI-TCGA,NCI-TCGA Cosmic
rs144228850	p.Arg281Trp	missense variant	-	NC_000002.12:g.120349491C>T	ESP,ExAC,TOPMed,gnomAD
rs560571608	p.Arg281Gln	missense variant	-	NC_000002.12:g.120349492G>A	1000Genomes,gnomAD
rs774682024	p.Leu282Pro	missense variant	-	NC_000002.12:g.120349495T>C	ExAC,gnomAD
rs546435911	p.Asp284Asn	missense variant	-	NC_000002.12:g.120349500G>A	1000Genomes
rs546435911	p.Asp284Asn	missense variant	-	NC_000002.12:g.120349500G>A	NCI-TCGA,NCI-TCGA Cosmic
rs201621303	p.Ser285Asn	missense variant	-	NC_000002.12:g.120349504G>A	1000Genomes,ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.His287Arg	missense variant	-	NC_000002.12:g.120349510A>G	NCI-TCGA
rs938023334	p.Arg288Cys	missense variant	-	NC_000002.12:g.120349512C>T	NCI-TCGA
rs1054158512	p.Arg288His	missense variant	-	NC_000002.12:g.120349513G>A	NCI-TCGA Cosmic
rs1054158512	p.Arg288His	missense variant	-	NC_000002.12:g.120349513G>A	TOPMed
rs938023334	p.Arg288Cys	missense variant	-	NC_000002.12:g.120349512C>T	TOPMed,gnomAD
rs1417490012	p.Ile289Val	missense variant	-	NC_000002.12:g.120349515A>G	gnomAD
rs1474349413	p.Arg290His	missense variant	-	NC_000002.12:g.120349519G>A	TOPMed,gnomAD
rs867394312	p.Arg290Cys	missense variant	-	NC_000002.12:g.120349518C>T	NCI-TCGA Cosmic
rs867394312	p.Arg290Cys	missense variant	-	NC_000002.12:g.120349518C>T	-
rs1472175416	p.Arg292Gln	missense variant	-	NC_000002.12:g.120349525G>A	gnomAD
rs761406590	p.Asp297Asn	missense variant	-	NC_000002.12:g.120349539G>A	NCI-TCGA,NCI-TCGA Cosmic
rs761406590	p.Asp297Asn	missense variant	-	NC_000002.12:g.120349539G>A	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Gly298Asp	missense variant	-	NC_000002.12:g.120349543G>A	NCI-TCGA
rs764629213	p.Arg299Gln	missense variant	-	NC_000002.12:g.120349546G>A	NCI-TCGA
rs867635709	p.Arg299Trp	missense variant	-	NC_000002.12:g.120349545C>T	TOPMed,gnomAD
rs764629213	p.Arg299Gln	missense variant	-	NC_000002.12:g.120349546G>A	ExAC,gnomAD
rs1313107093	p.Gln307Pro	missense variant	-	NC_000002.12:g.120349570A>C	gnomAD
rs766335999	p.Phe309Ser	missense variant	-	NC_000002.12:g.120349576T>C	ExAC,gnomAD
rs751413878	p.Ile310Val	missense variant	-	NC_000002.12:g.120349578A>G	ExAC,TOPMed,gnomAD
rs754755675	p.Ile310Thr	missense variant	-	NC_000002.12:g.120349579T>C	ExAC,gnomAD
rs1357534120	p.Arg313Ser	missense variant	-	NC_000002.12:g.120349587C>A	TOPMed,gnomAD
rs1317023671	p.Arg313His	missense variant	-	NC_000002.12:g.120349588G>A	NCI-TCGA
rs1317023671	p.Arg313His	missense variant	-	NC_000002.12:g.120349588G>A	gnomAD
rs1317023671	p.Arg313Leu	missense variant	-	NC_000002.12:g.120349588G>T	gnomAD
COSM3797901	p.Arg313Pro	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120349588G>C	NCI-TCGA Cosmic
rs756269241	p.Gly316Ser	missense variant	-	NC_000002.12:g.120349596G>A	ExAC,gnomAD
COSM4084543	p.Trp317Arg	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120349599T>C	NCI-TCGA Cosmic
rs61737545	p.Asn318Lys	missense variant	-	NC_000002.12:g.120349604C>A	ExAC,TOPMed,gnomAD
rs1257273235	p.Asn318Ser	missense variant	-	NC_000002.12:g.120349603A>G	gnomAD
rs777687482	p.Asn318Asp	missense variant	-	NC_000002.12:g.120349602A>G	ExAC,gnomAD
rs61737545	p.Asn318Lys	missense variant	-	NC_000002.12:g.120349604C>G	ExAC,TOPMed,gnomAD
rs771150890	p.Trp320Arg	missense variant	-	NC_000002.12:g.120349608T>C	ExAC
rs779036720	p.Ile321Val	missense variant	-	NC_000002.12:g.120349611A>G	ExAC
rs772370834	p.Ala323Val	missense variant	-	NC_000002.12:g.120349618C>T	ExAC,gnomAD
rs1418628487	p.Thr325Pro	missense variant	-	NC_000002.12:g.120349623A>C	gnomAD
rs17852732	p.Gly326Ser	missense variant	-	NC_000002.12:g.120349626G>A	ESP,ExAC,TOPMed,gnomAD
COSM4851081	p.Tyr328Cys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120349633A>G	NCI-TCGA Cosmic
rs1475923662	p.Gly329Arg	missense variant	-	NC_000002.12:g.120349635G>A	NCI-TCGA Cosmic
rs1475923662	p.Gly329Arg	missense variant	-	NC_000002.12:g.120349635G>A	TOPMed
rs201508130	p.Ser335Asn	missense variant	-	NC_000002.12:g.120349654G>A	1000Genomes,ExAC,gnomAD
rs762495009	p.Pro337Ser	missense variant	-	NC_000002.12:g.120349659C>T	ExAC,gnomAD
rs766134619	p.Ala338Pro	missense variant	-	NC_000002.12:g.120349662G>C	ExAC,gnomAD
rs375325463	p.Gly342Glu	missense variant	-	NC_000002.12:g.120349675G>A	ESP
rs1257723139	p.Gly342Arg	missense variant	-	NC_000002.12:g.120349674G>A	TOPMed
rs751219463	p.Val343Phe	missense variant	-	NC_000002.12:g.120349677G>T	ExAC,gnomAD
rs61737547	p.Pro344Thr	missense variant	-	NC_000002.12:g.120349680C>A	TOPMed,gnomAD
rs767197423	p.Gly345Ser	missense variant	-	NC_000002.12:g.120349683G>A	ExAC,TOPMed,gnomAD
rs777704323	p.Thr352Lys	missense variant	-	NC_000002.12:g.120349705C>A	ExAC,TOPMed
rs777704323	p.Thr352Met	missense variant	-	NC_000002.12:g.120349705C>T	NCI-TCGA,NCI-TCGA Cosmic
rs777704323	p.Thr352Met	missense variant	-	NC_000002.12:g.120349705C>T	ExAC,TOPMed
rs756005419	p.Thr352Ala	missense variant	-	NC_000002.12:g.120349704A>G	ExAC,gnomAD
rs1175488673	p.Ala353Val	missense variant	-	NC_000002.12:g.120349708C>T	gnomAD
rs375362335	p.Val354Leu	missense variant	-	NC_000002.12:g.120349710G>C	ESP,ExAC,TOPMed,gnomAD
rs779126855	p.Asn356Thr	missense variant	-	NC_000002.12:g.120349717A>C	ExAC,gnomAD
rs1394221213	p.Tyr358Cys	missense variant	-	NC_000002.12:g.120349723A>G	gnomAD
rs371205927	p.Arg359His	missense variant	-	NC_000002.12:g.120349726G>A	ESP,TOPMed,gnomAD
rs746066693	p.Met360Thr	missense variant	-	NC_000002.12:g.120349729T>C	ExAC,TOPMed,gnomAD
rs200244553	p.Met360Ile	missense variant	-	NC_000002.12:g.120349730G>A	1000Genomes,ExAC,gnomAD
COSM6087260	p.Arg361Leu	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120349732G>T	NCI-TCGA Cosmic
rs769057982	p.Asn364Lys	missense variant	-	NC_000002.12:g.120349742C>G	ExAC,gnomAD
NCI-TCGA novel	p.Pro365His	missense variant	-	NC_000002.12:g.120349744C>A	NCI-TCGA
rs1338075960	p.Pro365Thr	missense variant	-	NC_000002.12:g.120349743C>A	TOPMed
rs762584441	p.Gly366Ser	missense variant	-	NC_000002.12:g.120349746G>A	NCI-TCGA,NCI-TCGA Cosmic
rs762584441	p.Gly366Ser	missense variant	-	NC_000002.12:g.120349746G>A	ExAC,gnomAD
rs770518408	p.Gly366Val	missense variant	-	NC_000002.12:g.120349747G>T	ExAC,TOPMed,gnomAD
rs770518408	p.Gly366Asp	missense variant	-	NC_000002.12:g.120349747G>A	ExAC,TOPMed,gnomAD
rs759235725	p.Thr367Met	missense variant	-	NC_000002.12:g.120349750C>T	ExAC,TOPMed,gnomAD
NCI-TCGA novel	p.Asn369Lys	missense variant	-	NC_000002.12:g.120349757C>A	NCI-TCGA
rs1202723026	p.Thr375Ile	missense variant	-	NC_000002.12:g.120349774C>T	gnomAD
rs1468996997	p.Met380Ile	missense variant	-	NC_000002.12:g.120349790G>A	TOPMed,gnomAD
rs1275085699	p.Met380Val	missense variant	-	NC_000002.12:g.120349788A>G	gnomAD
rs1194163692	p.Met382Ile	missense variant	-	NC_000002.12:g.120349796G>A	gnomAD
NCI-TCGA novel	p.Asp386Tyr	missense variant	-	NC_000002.12:g.120349806G>T	NCI-TCGA
COSM1005985	p.Asp387Gly	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120349810A>G	NCI-TCGA Cosmic
COSM5072902	p.Glu388Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120349812G>A	NCI-TCGA Cosmic
rs1427512441	p.Ile391Val	missense variant	-	NC_000002.12:g.120349821A>G	gnomAD
rs369911045	p.Val392Ile	missense variant	-	NC_000002.12:g.120349824G>A	ESP,ExAC,TOPMed,gnomAD
rs373528779	p.Arg394Gln	missense variant	-	NC_000002.12:g.120349831G>A	ESP,TOPMed
rs765268608	p.Val396Met	missense variant	-	NC_000002.12:g.120349836G>A	ExAC,gnomAD
rs765268608	p.Val396Leu	missense variant	-	NC_000002.12:g.120349836G>C	ExAC,gnomAD
NCI-TCGA novel	p.Asn398Lys	missense variant	-	NC_000002.12:g.120349844C>A	NCI-TCGA
rs1305975626	p.Glu403Gln	missense variant	-	NC_000002.12:g.120349857G>C	TOPMed
COSM3565886	p.Glu403Lys	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120349857G>A	NCI-TCGA Cosmic
rs747340870	p.Gly405Ser	missense variant	-	NC_000002.12:g.120349863G>A	ExAC,gnomAD
rs747340870	p.Gly405Ser	missense variant	-	NC_000002.12:g.120349863G>A	NCI-TCGA
NCI-TCGA novel	p.Ala407Val	missense variant	-	NC_000002.12:g.120349870C>T	NCI-TCGA
rs781770753	p.Ala407Thr	missense variant	-	NC_000002.12:g.120349869G>A	ExAC,TOPMed,gnomAD
COSM6153562	p.Ala407Ser	missense variant	Variant assessed as Somatic; MODERATE impact.	NC_000002.12:g.120349869G>T	NCI-TCGA Cosmic

Disease or phenotype associated information

Disease ID	Disease Name	Disease Type	Source
C0001430	Adenoma	group	BEFREE
C0003125	Anorexia Nervosa	disease	LHGDN
C0006142	Malignant neoplasm of breast	disease	BEFREE
C0010308	Congenital Hypothyroidism	disease	RGD
C0020619	Hypogonadism	disease	LHGDN
C0032460	Polycystic Ovary Syndrome	disease	LHGDN
C0039590	Testicular Neoplasms	group	BEFREE
C0085215	Ovarian Failure, Premature	disease	LHGDN
C0265554	Ectrodactyly	disease	BEFREE
C0342200	Endemic Cretinism	disease	RGD
C0342549	Familial Testotoxicosis	disease	CTD_human
C0476089	Endometrial Carcinoma	disease	BEFREE
C0678222	Breast Carcinoma	disease	BEFREE
C1384583	Congenital absence of germinal epithelium of testes	disease	LHGDN
C1458155	Mammary Neoplasms	group	LHGDN
C1527249	Colorectal Cancer	disease	BEFREE
C2699510	Split-Hand/Foot Malformation	disease	BEFREE
C2931019	Split hand foot deformity 1	disease	BEFREE

Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO ID	GO Term	Evidence
GO:0005125	cytokine activity	IBA
GO:0005125	cytokine activity	TAS
GO:0005179	hormone activity	TAS
GO:0005515	protein binding	IPI
GO:0008083	growth factor activity	IEA
GO:0042803	protein homodimerization activity	IPI
GO:0046789	host cell surface receptor binding	TAS

GO:Biological Process

GO ID	GO Term	Evidence
GO:0001541	ovarian follicle development	NAS
GO:0006952	defense response	TAS
GO:0009267	cellular response to starvation	ISS
GO:0009611	response to wounding	IEP
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	IBA
GO:0030154	cell differentiation	NAS
GO:0032869	cellular response to insulin stimulus	ISS
GO:0032924	activin receptor signaling pathway	IDA
GO:0044320	cellular response to leptin stimulus	IEA
GO:0044650	adhesion of symbiont to host cell	IEA
GO:0045444	fat cell differentiation	ISS
GO:0046676	negative regulation of insulin secretion	ISS
GO:0046881	positive regulation of follicle-stimulating hormone secretion	IPI
GO:0046882	negative regulation of follicle-stimulating hormone secretion	IPI
GO:0048178	negative regulation of hepatocyte growth factor biosynthetic process	IDA
GO:0048599	oocyte development	IEA
GO:0060279	positive regulation of ovulation	ISS
GO:0060395	SMAD protein signal transduction	IBA
GO:2001235	positive regulation of apoptotic signaling pathway	IEA

GO:Cellular Component

GO ID	GO Term	Evidence
GO:0005576	extracellular region	TAS
GO:0005615	extracellular space	IBA
GO:0048471	perinuclear region of cytoplasm	IDA
GO:0071944	cell periphery	IEA

Reactome Pathway

Reactome ID	Reactome Term	Evidence
R-HSA-1502540	Signaling by Activin	TAS
R-HSA-1502540	Signaling by Activin	IEA
R-HSA-162582	Signal Transduction	TAS
R-HSA-162582	Signal Transduction	IEA
R-HSA-209822	Glycoprotein hormones	TAS
R-HSA-209952	Peptide hormone biosynthesis	TAS
R-HSA-2473224	Antagonism of Activin by Follistatin	TAS
R-HSA-2980736	Peptide hormone metabolism	TAS
R-HSA-392499	Metabolism of proteins	TAS
R-HSA-9006936	Signaling by TGF-beta family members	TAS
R-HSA-9006936	Signaling by TGF-beta family members	IEA

Drugs and compounds information

ID	Drug Name	Action	PubMed
C026486	1,2,5,6-dibenzanthracene	1,2,5,6-dibenzanthracene results in decreased expression of INHBB mRNA	26377693
C558048	1,7-diphenyl-4,6-heptadien-3-ol	1,7-diphenyl-4,6-heptadien-3-ol results in increased expression of INHBB mRNA	25575267
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of INHBB mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of INHBB mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of INHBB mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of INHBB mRNA	28628672
C032668	1-nitropyrene	1-nitropyrene results in increased expression of INHBB mRNA	19041380
C548651	2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester	2-(1'H-indole-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of INHBB mRNA	19933214
C404910	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane	2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of INHBB mRNA	20826375
C029497	2,3-bis(3'-hydroxybenzyl)butyrolactone	[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of INHBB mRNA	19167446
C016403	2,4-dinitrotoluene	2,4-dinitrotoluene affects the expression of INHBB mRNA	21346803
C007997	25-hydroxycholesterol	25-hydroxycholesterol results in increased expression of INHBB mRNA	19464342
C007997	25-hydroxycholesterol	25-hydroxycholesterol results in increased expression of INHBB protein	19464342
C583074	4,4'-hexafluorisopropylidene diphenol	4,4'-hexafluorisopropylidene diphenol results in decreased expression of INHBB mRNA	22504055
D015127	9,10-Dimethyl-1,2-benzanthracene	9,10-Dimethyl-1,2-benzanthracene results in increased expression of INHBB mRNA	22485181
C496492	abrine	abrine results in decreased expression of INHBB mRNA	31054353
D000082	Acetaminophen	Acetaminophen results in decreased expression of INHBB mRNA	21420995; 26690555;
D000082	Acetaminophen	Acetaminophen results in increased expression of INHBB mRNA	29067470
D000082	Acetaminophen	Acetaminophen affects the expression of INHBB mRNA	17562736
D020106	Acrylamide	Acrylamide results in decreased expression of INHBB mRNA	28959563
D016604	Aflatoxin B1	Aflatoxin B1 affects the expression of INHBB protein	20106945
D016604	Aflatoxin B1	Aflatoxin B1 results in decreased expression of INHBB mRNA	19770486
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of INHBB mRNA	16483693
D000661	Amphetamine	Amphetamine results in increased expression of INHBB mRNA	30779732
C059765	amphotericin B, deoxycholate drug combination	amphotericin B, deoxycholate drug combination results in increased expression of INHBB mRNA	22863853
D001151	Arsenic	Arsenic affects the expression of INHBB protein	24675094
D000077237	Arsenic Trioxide	Arsenic Trioxide results in increased expression of INHBB mRNA	29633893
C015001	arsenite	[arsenite co-treated with Benzo(a)pyrene] results in decreased expression of INHBB mRNA	15894712
C015001	arsenite	arsenite results in decreased expression of INHBB mRNA	15894712
D001280	Atrazine	Atrazine results in increased expression of INHBB mRNA	18585445
D001397	Azoxymethane	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of INHBB mRNA	29950665
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of INHBB mRNA	20106945; 21632981; 22316170;
D001564	Benzo(a)pyrene	[arsenite co-treated with Benzo(a)pyrene] results in decreased expression of INHBB mRNA	15894712
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in decreased expression of INHBB mRNA	19770486; 21715664;
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of INHBB mRNA	15894712
D019324	beta-Naphthoflavone	beta-Naphthoflavone results in decreased expression of INHBB mRNA	19737606
D019324	beta-Naphthoflavone	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of INHBB mRNA	18164116
C543008	bis(4-hydroxyphenyl)sulfone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of INHBB mRNA	28628672
C006780	bisphenol A	bisphenol A results in decreased secretion of INHBB protein	28637469
C006780	bisphenol A	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of INHBB mRNA	28628672
C006780	bisphenol A	bisphenol A results in decreased methylation of INHBB promoter	27312807
C006780	bisphenol A	bisphenol A results in increased expression of INHBB mRNA	20826375
C006780	bisphenol A	bisphenol A affects the expression of INHBB mRNA	21786754
C006780	bisphenol A	bisphenol A affects the expression of INHBB mRNA	25181051
C006780	bisphenol A	bisphenol A results in decreased expression of INHBB mRNA	30816183
C006780	bisphenol A	bisphenol A results in increased expression of INHBB mRNA	28641706
C000611646	bisphenol F	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of INHBB mRNA	28628672
C018475	butyraldehyde	butyraldehyde results in decreased expression of INHBB mRNA	26079696
C584509	C646 compound	C646 compound results in decreased expression of INHBB mRNA	26191083
D002104	Cadmium	Cadmium results in increased expression of INHBB mRNA	22562489
D002104	Cadmium	Cadmium results in decreased expression of INHBB protein	26424772
D002104	Cadmium	flavocoxid inhibits the reaction [Cadmium results in decreased expression of INHBB protein]	26424772
D019256	Cadmium Chloride	Cadmium Chloride results in decreased expression of INHBB protein	26424772
D019256	Cadmium Chloride	flavocoxid inhibits the reaction [Cadmium Chloride results in decreased expression of INHBB protein]	26424772
D002251	Carbon Tetrachloride	Carbon Tetrachloride results in increased expression of INHBB mRNA	31150632
D002251	Carbon Tetrachloride	schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of INHBB mRNA]	31150632
D002509	Cephaloridine	Cephaloridine results in decreased expression of INHBB mRNA	18500788
D002794	Choline	[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of INHBB mRNA	29127188
D002794	Choline	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of INHBB mRNA	20938992
D002922	Ciguatoxins	Ciguatoxins affects the expression of INHBB mRNA	18353800
D002945	Cisplatin	Cisplatin results in decreased expression of INHBB mRNA	27392435
C018021	cobaltous chloride	cobaltous chloride results in decreased expression of INHBB mRNA	24386269
D003300	Copper	Copper results in decreased expression of INHBB mRNA	30556269
D003300	Copper	Copper results in increased expression of INHBB mRNA	22465980
D019327	Copper Sulfate	Copper Sulfate results in increased expression of INHBB mRNA	19549813
D003375	Coumestrol	[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of INHBB mRNA	19167446
D065366	Cryptoxanthins	Cryptoxanthins inhibits the reaction [Lipopolysaccharides results in decreased expression of INHBB mRNA]	26686910
D065366	Cryptoxanthins	Cryptoxanthins results in increased expression of INHBB mRNA	26686910
D003471	Cuprizone	Cuprizone results in decreased expression of INHBB mRNA	26577399; 27523638;
C009160	cyclonite	cyclonite results in decreased expression of INHBB mRNA	25559034
D016572	Cyclosporine	Cyclosporine results in increased expression of INHBB mRNA	20106945; 21632981; 25562108;
C017160	cypermethrin	[cypermethrin co-treated with Diethylhexyl Phthalate] results in decreased expression of INHBB mRNA	24641848
C017160	cypermethrin	cypermethrin results in decreased expression of INHBB mRNA	24641848
C017160	cypermethrin	cypermethrin results in decreased expression of INHBB protein	24641848
C010902	decabromobiphenyl ether	decabromobiphenyl ether results in decreased expression of INHBB mRNA	24317228
D003907	Dexamethasone	Dexamethasone results in increased expression of INHBB mRNA	25047013
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of INHBB mRNA	28628672
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of INHBB mRNA	28628672
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of INHBB mRNA	28628672
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of INHBB mRNA	28628672
D016264	Dextran Sulfate	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of INHBB mRNA	29950665
D036381	Diarylheptanoids	Diarylheptanoids results in increased expression of INHBB mRNA	23552522
D036381	Diarylheptanoids	ESR1 protein affects the reaction [Diarylheptanoids results in increased expression of INHBB mRNA]	23552522
D003993	Dibutyl Phthalate	Dibutyl Phthalate results in decreased expression of INHBB mRNA	21266533
D003633	Dichlorodiphenyl Dichloroethylene	Dichlorodiphenyl Dichloroethylene results in decreased expression of INHBB mRNA	16519141; 19877505;
D004008	Diclofenac	Diclofenac results in increased expression of INHBB mRNA	26934552
D004008	Diclofenac	Diclofenac results in increased expression of INHBB mRNA	30723492
D004041	Dietary Fats	Dietary Fats results in decreased expression of INHBB mRNA	25016146
D004041	Dietary Fats	[Streptozocin co-treated with Dietary Fats] results in increased expression of INHBB mRNA	29127188
D019422	Dietary Sucrose	Dietary Sucrose results in increased expression of INHBB mRNA	26033743
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of INHBB protein	26678702
D004051	Diethylhexyl Phthalate	[cypermethrin co-treated with Diethylhexyl Phthalate] results in decreased expression of INHBB mRNA	24641848
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of INHBB mRNA	24641848
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in decreased expression of INHBB protein	24641848
C014476	diethyl maleate	diethyl maleate results in decreased expression of INHBB mRNA	25270620
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of INHBB mRNA	24535843
D004052	Diethylnitrosamine	[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of INHBB mRNA	18164116
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of INHBB mRNA	25242112
D004054	Diethylstilbestrol	Diethylstilbestrol results in decreased expression of INHBB mRNA	17255206
D004054	Diethylstilbestrol	Diethylstilbestrol results in increased expression of INHBB mRNA	15289156
D004054	Diethylstilbestrol	Diethylstilbestrol promotes the reaction [FSHB protein results in increased expression of INHBB mRNA]	15878960
D004147	Dioxins	Dioxins results in decreased expression of INHBB protein	21262597
D004958	Estradiol	Estradiol affects the expression of INHBB mRNA	25321415
D004958	Estradiol	[Estradiol co-treated with TGFB1 protein] results in decreased expression of INHBB mRNA	30165855
D004958	Estradiol	ESR1 protein affects the reaction [Estradiol results in increased expression of INHBB mRNA]	23552522
D004958	Estradiol	Estradiol results in decreased expression of INHBB mRNA	17255206
D004958	Estradiol	Estradiol results in increased expression of INHBB mRNA	15289156; 20049119; 20826375; 23144751; 23552522; 25210133; 25575267;
D004964	Estriol	Estriol results in increased expression of INHBB mRNA	25575267
D000431	Ethanol	Ethanol affects the expression of INHBB mRNA	30319688
D000431	Ethanol	Ethanol results in increased expression of INHBB mRNA	30319688
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of INHBB mRNA	16467188; 17555576; 17942748;
D004997	Ethinyl Estradiol	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of INHBB mRNA	17942748
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in decreased expression of INHBB mRNA	28522409
D004997	Ethinyl Estradiol	Ethinyl Estradiol results in increased expression of INHBB mRNA	17351261
C544478	flavocoxid	flavocoxid inhibits the reaction [Cadmium Chloride results in decreased expression of INHBB protein]	26424772
C544478	flavocoxid	flavocoxid inhibits the reaction [Cadmium results in decreased expression of INHBB protein]	26424772
D005492	Folic Acid	[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of INHBB mRNA	29127188
D005492	Folic Acid	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of INHBB mRNA	20938992
D004397	Fonofos	Fonofos results in increased methylation of INHBB promoter	22847954
D019833	Genistein	Genistein results in decreased expression of INHBB mRNA	22228119
D019833	Genistein	Genistein results in increased expression of INHBB mRNA	15289156
D006108	Graphite	Graphite affects the expression of INHBB mRNA	29933104
D006534	Heptachlor Epoxide	Heptachlor Epoxide results in increased expression of INHBB mRNA	25270620
D006861	Hydrogen Peroxide	Hydrogen Peroxide results in increased expression of INHBB mRNA	12414654
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of INHBB mRNA	28628672
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of INHBB mRNA	28628672
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of INHBB mRNA	28628672
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of INHBB mRNA	28628672
D007545	Isoproterenol	Isoproterenol results in increased expression of INHBB mRNA	20003209
C008261	lead acetate	lead acetate results in decreased expression of INHBB mRNA	25270620
C008261	lead acetate	lead acetate results in decreased expression of and results in decreased secretion of INHBB protein	29273543
C008261	lead acetate	lead acetate results in decreased expression of and results in decreased secretion of [INHBB protein binds to INHA protein]	29273543
C008261	lead acetate	lead acetate results in decreased expression of INHBB mRNA	29273543
D000077339	Leflunomide	Leflunomide results in increased expression of INHBB mRNA	28988120
D008070	Lipopolysaccharides	Cryptoxanthins inhibits the reaction [Lipopolysaccharides results in decreased expression of INHBB mRNA]	26686910
D008070	Lipopolysaccharides	Lipopolysaccharides results in decreased expression of INHBB mRNA	26686910
D008715	Methionine	[Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of INHBB mRNA	29127188
D008715	Methionine	[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of INHBB mRNA	20938992
D008741	Methyl Methanesulfonate	Methyl Methanesulfonate results in decreased expression of INHBB mRNA	26011545
C583365	N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of INHBB mRNA	29244179
D037742	Nanotubes, Carbon	Nanotubes, Carbon analog affects the expression of INHBB mRNA	25620056
D037742	Nanotubes, Carbon	Nanotubes, Carbon analog results in increased expression of INHBB mRNA	25554681
D037742	Nanotubes, Carbon	Nanotubes, Carbon results in increased expression of INHBB mRNA	25554681; 25620056;
D009532	Nickel	Nickel affects the expression of INHBB mRNA	14575637
D009532	Nickel	Nickel results in decreased expression of INHBB mRNA	24768652; 25583101;
D009532	Nickel	trichostatin A inhibits the reaction [Nickel affects the expression of INHBB mRNA]	14575637
C025256	nonylphenol	nonylphenol analog results in increased expression of INHBB protein	25242005
C464660	obeticholic acid	obeticholic acid results in increased expression of INHBB mRNA	27939613
D000077150	Oxaliplatin	[Oxaliplatin co-treated with Topotecan] results in increased expression of INHBB mRNA	25729387
D010100	Oxygen	[NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of INHBB mRNA	30529165
D010278	Parathion	Parathion results in increased methylation of INHBB promoter	22847954
C101816	perfluoro-n-nonanoic acid	perfluoro-n-nonanoic acid results in decreased expression of INHBB mRNA	20580666
C101816	perfluoro-n-nonanoic acid	perfluoro-n-nonanoic acid results in decreased expression of INHBB protein	20580666
D010795	Phthalic Acids	Phthalic Acids results in increased expression of INHBB mRNA	22112501
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of INHBB mRNA	19710929
C006253	pirinixic acid	pirinixic acid results in decreased expression of INHBB mRNA	25270620
C006253	pirinixic acid	pirinixic acid results in increased expression of INHBB mRNA	18445702; 23811191;
D010936	Plant Extracts	Plant Extracts results in decreased expression of INHBB mRNA	23557933
C027373	potassium chromate(VI)	potassium chromate(VI) results in increased expression of INHBB mRNA	22714537
C009006	potassium perchlorate	potassium perchlorate results in decreased expression of INHBB mRNA	29673971
D011285	Pregnenolone Carbonitrile	Pregnenolone Carbonitrile results in increased expression of INHBB mRNA	28903501
D011374	Progesterone	Progesterone results in increased expression of INHBB mRNA	21795739
D011441	Propylthiouracil	AKT1 protein mutant form promotes the reaction [Propylthiouracil results in increased expression of INHBB mRNA]	20951798
D011441	Propylthiouracil	Propylthiouracil results in increased expression of INHBB mRNA	20951798
D011441	Propylthiouracil	Propylthiouracil affects the expression of INHBB mRNA	7819453
D011441	Propylthiouracil	Propylthiouracil results in increased expression of INHBB mRNA	24780913
D011794	Quercetin	Quercetin results in increased expression of INHBB mRNA	21632981
D018967	Risperidone	Risperidone results in increased expression of [INHA protein binds to INHBB protein]	18838228
C015499	schizandrin B	schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of INHBB mRNA]	31150632
D012822	Silicon Dioxide	Silicon Dioxide analog results in decreased expression of INHBB mRNA	23806026; 25895662;
D012822	Silicon Dioxide	Silicon Dioxide results in increased expression of INHBB mRNA	23221170
D018030	Silver Compounds	Silver Compounds results in increased expression of INHBB mRNA	30090567
C017947	sodium arsenite	sodium arsenite results in decreased expression of INHBB mRNA	16014739
D013311	Streptozocin	[Streptozocin co-treated with Dietary Fats] results in increased expression of INHBB mRNA	29127188
D013629	Tamoxifen	Tamoxifen affects the expression of INHBB mRNA	20937368
D013629	Tamoxifen	Tamoxifen results in increased expression of INHBB mRNA	17555576
C012568	terbufos	terbufos results in increased methylation of INHBB promoter	22847954
D020122	tert-Butylhydroperoxide	tert-Butylhydroperoxide results in increased expression of INHBB mRNA	12414654
D013739	Testosterone	Testosterone results in decreased expression of INHBB mRNA	22138414
C020806	tetrabromobisphenol A	tetrabromobisphenol A results in decreased expression of INHBB mRNA	25172293
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in decreased expression of INHBB mRNA	20106945; 21632981;
D013749	Tetrachlorodibenzodioxin	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of INHBB mRNA	17942748
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of INHBB mRNA	19933214
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of INHBB mRNA	21215274
C009495	titanium dioxide	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of INHBB mRNA	29950665
C009495	titanium dioxide	titanium dioxide results in increased expression of INHBB mRNA	23557971
D014028	Tobacco Smoke Pollution	Tobacco Smoke Pollution results in increased expression of INHBB mRNA	28065790
D019772	Topotecan	[Oxaliplatin co-treated with Topotecan] results in increased expression of INHBB mRNA	25729387
D019772	Topotecan	Topotecan results in increased expression of INHBB mRNA	25729387
D014118	Toxins, Biological	Toxins, Biological affects the expression of INHBB mRNA	19682533
D014212	Tretinoin	Tretinoin results in increased expression of INHBB mRNA	20530235
D014212	Tretinoin	Tretinoin results in decreased expression of INHBB mRNA	23830798
C011559	tributyltin	tributyltin results in increased expression of INHBB mRNA	31129395
C012589	trichostatin A	trichostatin A inhibits the reaction [Nickel affects the expression of INHBB mRNA]	14575637
C012589	trichostatin A	trichostatin A results in decreased expression of INHBB mRNA	15901671
D014284	Triiodothyronine	FSHB protein promotes the reaction [Triiodothyronine results in increased expression of INHBB mRNA]	7531505
D014284	Triiodothyronine	Triiodothyronine promotes the reaction [FSHB protein results in increased expression of INHBB mRNA]	7531505
D014284	Triiodothyronine	Triiodothyronine results in increased expression of INHBB mRNA	7531505
C015559	trimellitic anhydride	trimellitic anhydride results in increased expression of INHBB mRNA	19042947
C016805	tris(1,3-dichloro-2-propyl)phosphate	tris(1,3-dichloro-2-propyl)phosphate results in increased expression of INHBB mRNA	26743178
C016805	tris(1,3-dichloro-2-propyl)phosphate	tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of INHBB mRNA	26179874
D014520	Urethane	Urethane results in decreased expression of INHBB mRNA	28818685
D014527	Uric Acid	INHBB gene SNP affects the abundance of Uric Acid	23263486
D014635	Valproic Acid	Valproic Acid results in decreased expression of INHBB mRNA	15901671
D014638	Vanadates	Vanadates results in increased expression of INHBB mRNA	22714537
C029297	vinylidene chloride	vinylidene chloride results in increased expression of INHBB mRNA	26682919
D024483	Vitamin K 3	Vitamin K 3 affects the expression of INHBB mRNA	20044591
D024483	Vitamin K 3	Vitamin K 3 results in increased expression of INHBB mRNA	12414654
D014874	Water Pollutants, Chemical	Water Pollutants, Chemical results in increased expression of INHBB mRNA	24525044

Functional annotations

Keywords

Keyword ID	Keyword Term
KW-0165	Cleavage on pair of basic residues
KW-0903	Direct protein sequencing
KW-1015	Disulfide bond
KW-0325	Glycoprotein
KW-0339	Growth factor
KW-0372	Hormone
KW-1185	Reference proteome
KW-0964	Secreted
KW-0732	Signal

Interpro

InterPro ID	InterPro Term
IPR029034	Cystine-knot_cytokine
IPR000381	Inhibin_betaB
IPR001839	TGF-b_C
IPR001111	TGF-b_propeptide
IPR015615	TGF-beta-rel
IPR017948	TGFb_CS

PROSITE

PROSITE ID	PROSITE Term
PS00250	TGF_BETA_1
PS51362	TGF_BETA_2

Pfam

Pfam ID	Pfam Term
PF00019	TGF_beta
PF00688	TGFb_propeptide

Gene: INHBB

Basic information

Gene expression information

Gene expression in different tissues (GTEx V7)

Gene expression in different tissues (ENCODE)

Protein structural annotations

3D structure in PDB database

There is no related protein structure for this gene.

Protein disorder information

Orthologous information

Other genetic variants/mutations

Disease or phenotype associated information

Gene Ontology (GO)/biological pathways

GO:Molecular Function

GO:Biological Process

GO:Cellular Component

Reactome Pathway

Drugs and compounds information

Functional annotations

Keywords

Interpro

PROSITE

Pfam

Protein-protein interaction

Protein-miRNA interaction