| Tag | Content |
|---|---|
| Uniprot ID | P10600; Q8WV88; |
| Entrez ID | 7043 |
| Genbank protein ID | CAA33024.1; AAO13495.1; AAH18503.1; AAM96819.1; AAA61161.1; CAA32362.1; AAP35951.1; AAC79727.1; |
| Genbank nucleotide ID | NM_003239.4; NM_001329939.1; NM_001329938.1; |
| Ensembl protein ID | ENSP00000238682; ENSP00000451110; |
| Ensembl nucleotide ID | ENSG00000119699 |
| Gene name | Transforming growth factor beta-3 proprotein |
| Gene symbol | TGFB3 |
| Organism | Homo sapiens |
| NCBI taxa ID | 9606 |
| Cleft type | CPO,CL/P |
| Developmental stage | |
| Data sources | Manually collected |
| Reference | 11396489; 18480962; 22143699; 20082468; 9683588; 14659070; 20170386; 16247549; 23023602; |
| Functional description | Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively. |
| Sequence | MKMHLQRALV VLALLNFATV SLSLSTCTTL DFGHIKKKRV EAIRGQILSK LRLTSPPEPT 60 VMTHVPYQVL ALYNSTRELL EEMHGEREEG CTQENTESEY YAKEIHKFDM IQGLAEHNEL 120 AVCPKGITSK VFRFNVSSVE KNRTNLFRAE FRVLRVPNPS SKRNEQRIEL FQILRPDEHI 180 AKQRYIGGKN LPTRGTAEWL SFDVTDTVRE WLLRRESNLG LEISIHCPCH TFQPNGDILE 240 NIHEVMEIKF KGVDNEDDHG RGDLGRLKKQ KDHHNPHLIL MMIPPHRLDN PGQGGQRKKR 300 ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST 360 VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS 412 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.