| Tag | Content |
|---|---|
| Uniprot ID | P17125 |
| Entrez ID | |
| Genbank protein ID | AAA40422.1 |
| Genbank nucleotide ID | |
| Ensembl protein ID | |
| Ensembl nucleotide ID | |
| Gene name | Transforming growth factor beta-3 proprotein |
| Gene symbol | Tgfb3 |
| Organism | Mus musculus |
| NCBI taxa ID | 10090 |
| Cleft type | CPO |
| Developmental stage | E11.5, E12.5, E14.0, E13.5, E14.5, E15.5 |
| Data sources | Manually collected |
| Reference | 7493022; 7493021; 25523394; 18343643; 17967447; 22223248; |
| Functional description | Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively. |
| Sequence | MHLQRALVVL ALLNLATISL SLSTCTTLDF GHIKKKRVEA IRGQILSKLR LTSPPEPSVM 60 THVPYQVLAL YNSTRELLEE MHGEREEGCT QETSESEYYA KEIHKFDMIQ GLAEHNELAV 120 CPKGITSKVF RFNVSSVEKN GTNLFRAEFR VLRVPNPSSK RTEQRIELFQ ILRPDEHIAK 180 QRYIGGKNLP TRGTAEWLSF DVTDTVREWL LRRESNLGLE ISIHCPCHTF QPNGDILENV 240 HEVMEIKFKG VDNEDDHGRG DLGRLKKQKD HHNPHLILMM IPPHRLDSPG QGSQRKKRAL 300 DTNYCFRNLE ENCCVRPLYI DFRQDLGWKW VHEPKGYYAN FCSGPCPYLR SADTTHSTVL 360 GLYNTLNPEA SASPCCVPQD LEPLTILYYV GRTPKVEQLS NMVVKSCKCS |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.